KEGG   Peromyscus leucopus (white-footed mouse): 114704437
Entry
114704437         CDS       T07241                                 
Symbol
Casp8
Name
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
pleu  Peromyscus leucopus (white-footed mouse)
Pathway
pleu01524  Platinum drug resistance
pleu04115  p53 signaling pathway
pleu04210  Apoptosis
pleu04215  Apoptosis - multiple species
pleu04217  Necroptosis
pleu04620  Toll-like receptor signaling pathway
pleu04621  NOD-like receptor signaling pathway
pleu04622  RIG-I-like receptor signaling pathway
pleu04623  Cytosolic DNA-sensing pathway
pleu04625  C-type lectin receptor signaling pathway
pleu04657  IL-17 signaling pathway
pleu04668  TNF signaling pathway
pleu04932  Non-alcoholic fatty liver disease
pleu04936  Alcoholic liver disease
pleu05010  Alzheimer disease
pleu05016  Huntington disease
pleu05022  Pathways of neurodegeneration - multiple diseases
pleu05132  Salmonella infection
pleu05134  Legionellosis
pleu05142  Chagas disease
pleu05145  Toxoplasmosis
pleu05152  Tuberculosis
pleu05160  Hepatitis C
pleu05161  Hepatitis B
pleu05162  Measles
pleu05163  Human cytomegalovirus infection
pleu05164  Influenza A
pleu05165  Human papillomavirus infection
pleu05167  Kaposi sarcoma-associated herpesvirus infection
pleu05168  Herpes simplex virus 1 infection
pleu05169  Epstein-Barr virus infection
pleu05170  Human immunodeficiency virus 1 infection
pleu05200  Pathways in cancer
pleu05203  Viral carcinogenesis
pleu05416  Viral myocarditis
pleu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    114704437 (Casp8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    114704437 (Casp8)
   04215 Apoptosis - multiple species
    114704437 (Casp8)
   04217 Necroptosis
    114704437 (Casp8)
   04115 p53 signaling pathway
    114704437 (Casp8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114704437 (Casp8)
   04621 NOD-like receptor signaling pathway
    114704437 (Casp8)
   04622 RIG-I-like receptor signaling pathway
    114704437 (Casp8)
   04623 Cytosolic DNA-sensing pathway
    114704437 (Casp8)
   04625 C-type lectin receptor signaling pathway
    114704437 (Casp8)
   04657 IL-17 signaling pathway
    114704437 (Casp8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114704437 (Casp8)
   05203 Viral carcinogenesis
    114704437 (Casp8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114704437 (Casp8)
   05161 Hepatitis B
    114704437 (Casp8)
   05160 Hepatitis C
    114704437 (Casp8)
   05164 Influenza A
    114704437 (Casp8)
   05162 Measles
    114704437 (Casp8)
   05168 Herpes simplex virus 1 infection
    114704437 (Casp8)
   05163 Human cytomegalovirus infection
    114704437 (Casp8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114704437 (Casp8)
   05169 Epstein-Barr virus infection
    114704437 (Casp8)
   05165 Human papillomavirus infection
    114704437 (Casp8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114704437 (Casp8)
   05134 Legionellosis
    114704437 (Casp8)
   05152 Tuberculosis
    114704437 (Casp8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114704437 (Casp8)
   05142 Chagas disease
    114704437 (Casp8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114704437 (Casp8)
   05016 Huntington disease
    114704437 (Casp8)
   05022 Pathways of neurodegeneration - multiple diseases
    114704437 (Casp8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114704437 (Casp8)
   05416 Viral myocarditis
    114704437 (Casp8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114704437 (Casp8)
   04932 Non-alcoholic fatty liver disease
    114704437 (Casp8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    114704437 (Casp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pleu01002]
    114704437 (Casp8)
Enzymes [BR:pleu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     114704437 (Casp8)
Peptidases and inhibitors [BR:pleu01002]
 Cysteine peptidases
  Family C14: caspase family
   114704437 (Casp8)
SSDB
Motif
Pfam: Peptidase_C14 DED
Other DBs
NCBI-GeneID: 114704437
NCBI-ProteinID: XP_028741531
LinkDB
Position
13:complement(53309402..53341172)
AA seq 483 aa
MDFSSCLYEIAEHLGSDELAALKFLCLDHIPQRRLEPIEDALMLFQGLQERGLLEEGNLS
FLKELLFLINRLDLLTKVLNTSKEEMVRDLRILDRAQVSPYRVMLLKLSEDVVSSELKEI
KFFLEEKLPKYKLHDNTSLLDIFVEMEKRLILSDDNLDALKSICFRVKKSLLGRIKDYEL
SGRGRSMSLEGAAELPVSFSDGESCFRMSAEMFDSLGEQDSQLQVSDKIYQMKSKPRGYC
VIFNNNDFSKAREDVPKLHTIKDRKGTNYDREALTETFKELHFETVSYQDSTANEIREVL
RSYQSKDHKDRDCFICCILSHGDKGIIYGTDGKEASIYELTSYFTGSKCPSLAGKPKIFF
IQACQGDSYQRAVPVETDSEGKDSDLDIDSLSQKSYIPDEADFLLGMATVKNCVSYRDPT
RGTWYIQSLCQSLRQRCPRGDDILSILTGVNYDVSNKDDRKNMGKQMPQPIFTLRKKLFF
PPN
NT seq 1452 nt   +upstreamnt  +downstreamnt
atggatttcagcagctgcctttacgaaattgctgaacacctgggcagtgatgaactggcc
gccctcaagttcctgtgtttggaccacatcccgcagaggaggctggagcccatcgaggat
gccttgatgctatttcagggactgcaggaaagggggctgttggaggaaggcaatctgtcc
ttcctgaaggagctgcttttcctcatcaatcggctggacctgctgaccaaagtcctaaac
accagcaaggaggagatggtgagggatctgcggattctagacagagcccaggtttctccc
tacagggtcatgctcttaaagctctcggaagatgtagtctcatcagagttgaaagagatt
aagttttttttggaagaaaagctccccaaatataagctgcatgataacacgagcttgctt
gacattttcgtggaaatggagaagaggctcatcctgtcggatgacaacttggacgccctg
aaatcgatctgtttccgggtcaaaaagagcctgctggggaggatcaaggactatgaacta
tcaggcagagggagaagcatgagcctcgagggagcggccgagctgccggtgtccttttcg
gacggggagagctgcttcagaatgtcggcagaaatgttcgactccctgggagaacaagac
agccagctgcaggtatcagacaagatttaccaaatgaagagcaaacctcggggttactgt
gtgatcttcaacaataacgacttcagcaaggcgcgggaggacgtgcccaaacttcacacg
ataaaggacaggaaaggaaccaactatgacagagaggctttgactgagacctttaaggag
cttcattttgagaccgtgtcttaccaagactccacggcaaatgaaatccgtgaggttcta
agatcctaccaaagcaaggaccacaaggacagagactgcttcatctgctgcatcctctcc
cacggagacaaaggcatcatctacggcacggacgggaaggaagcatccatctatgaactg
acctcctacttcactggttcaaagtgcccttccctggctggaaaacccaaaatctttttt
atccaggcttgccaaggggacagttaccagagagctgtgcctgtcgagactgactcagag
ggcaaggacagtgatttagacatagactccttatctcaaaagagctatattccagatgag
gccgactttctgctggggatggctactgtgaaaaactgtgtttcctaccgagatcccacg
cgtggaacctggtacatccagtccctgtgccagagcctgaggcaaagatgtccccgaggc
gacgatattctcagcatcctgactggggtgaactacgatgtgagcaataaagatgacagg
aagaacatggggaagcagatgcctcagcccatcttcacactacggaagaagcttttcttc
cctcctaactga

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