Peromyscus leucopus (white-footed mouse): 114704659
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Entry
114704659 CDS
T07241
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu01522
Endocrine resistance
pleu04012
ErbB signaling pathway
pleu04062
Chemokine signaling pathway
pleu04148
Efferocytosis
pleu04151
PI3K-Akt signaling pathway
pleu04360
Axon guidance
pleu04370
VEGF signaling pathway
pleu04510
Focal adhesion
pleu04670
Leukocyte transendothelial migration
pleu04810
Regulation of actin cytoskeleton
pleu04935
Growth hormone synthesis, secretion and action
pleu05100
Bacterial invasion of epithelial cells
pleu05135
Yersinia infection
pleu05146
Amoebiasis
pleu05163
Human cytomegalovirus infection
pleu05165
Human papillomavirus infection
pleu05170
Human immunodeficiency virus 1 infection
pleu05200
Pathways in cancer
pleu05202
Transcriptional misregulation in cancer
pleu05205
Proteoglycans in cancer
pleu05208
Chemical carcinogenesis - reactive oxygen species
pleu05222
Small cell lung cancer
pleu05417
Lipid and atherosclerosis
pleu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
114704659 (Ptk2)
04370 VEGF signaling pathway
114704659 (Ptk2)
04151 PI3K-Akt signaling pathway
114704659 (Ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
114704659 (Ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
114704659 (Ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
114704659 (Ptk2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
114704659 (Ptk2)
04062 Chemokine signaling pathway
114704659 (Ptk2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
114704659 (Ptk2)
09158 Development and regeneration
04360 Axon guidance
114704659 (Ptk2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114704659 (Ptk2)
05202 Transcriptional misregulation in cancer
114704659 (Ptk2)
05205 Proteoglycans in cancer
114704659 (Ptk2)
05208 Chemical carcinogenesis - reactive oxygen species
114704659 (Ptk2)
09162 Cancer: specific types
05222 Small cell lung cancer
114704659 (Ptk2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
114704659 (Ptk2)
05163 Human cytomegalovirus infection
114704659 (Ptk2)
05165 Human papillomavirus infection
114704659 (Ptk2)
09171 Infectious disease: bacterial
05135 Yersinia infection
114704659 (Ptk2)
05100 Bacterial invasion of epithelial cells
114704659 (Ptk2)
09174 Infectious disease: parasitic
05146 Amoebiasis
114704659 (Ptk2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114704659 (Ptk2)
05418 Fluid shear stress and atherosclerosis
114704659 (Ptk2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
114704659 (Ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pleu01001
]
114704659 (Ptk2)
01009 Protein phosphatases and associated proteins [BR:
pleu01009
]
114704659 (Ptk2)
Enzymes [BR:
pleu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114704659 (Ptk2)
Protein kinases [BR:
pleu01001
]
Non-receptor tyrosine kinases
FAK family
114704659 (Ptk2)
Protein phosphatases and associated proteins [BR:
pleu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
114704659 (Ptk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
114704659
NCBI-ProteinID:
XP_028741833
LinkDB
All DBs
Position
20:complement(30374562..30595756)
Genome browser
AA seq
1140 aa
AA seq
DB search
MLLERAGQEALRSTGAICMEKSGCSPFPVCWAKEYDRYLASSKRMAAAYLDPNLNHTPSS
STKSHLGTGMERSPGAMERVLKVFHYFESSSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSGVNHCQHKVKKARRFLPLVFCSLEPPPTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMES
RRQATVSWESGGNDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGIPA
MAGSIYPGQASLLDQTELWNHRPQEMSMWQPNVEDSAALDLRGMGQVLPPHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLSNLASIGSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLV
KAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTHREIEMAQKLLNS
DLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQARPH
NT seq
3423 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggagcgggcaggccaagaggccctgagatctacaggtgccatctgtatggag
aaaagcggctgtagtccatttccagtgtgttgggctaaagaatatgacagatacctagca
tctagcaaaagaatggcagctgcttatcttgatccaaacttgaatcatacaccaagttca
agtactaagtctcacctgggtactggcatggaacggtcccctggtgcaatggagcgagta
ttaaaggtctttcattattttgaaagcagtagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaag
gtaaagcacgtagcctgctatggatttcgcctcagtcatctgcgatcagaggaagttcac
tggctgcatgtggatatgggagtctccagtgtgagggagaaatatgaactcgcccaccca
ccagaggaatggaaatatgagttgagaattcgttacttgccaaaaggatttctaaaccag
tttactgaagataaaccaacattgaatttcttctatcaacaggtgaagagtgactacatg
ctagagatagccgatcaagtagaccaagaaatagctttgaagttgggttgtctggaaatt
aggagatcctactgggagatgcggggcaatgccctagagaagaagtccaactatgaagtg
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaacactaagaaaactgatccagcaaacatttaggcagtttgccaaccttaataga
gaagaaagcatcctgaaattctttgagattctctctccggtgtacagatttgacaaagaa
tgcttcaagtgtgcccttgggtcaagttggattatttccgtggaactggcgattggccca
gaagaagggatcagttacctgacagacaagggctgcaatcccacacacctagccgacttc
aatcaagtgcagaccattcagtattcaaatagtgaagacaaagacaggaaaggaatgcta
caactcaaaattgccggtgcccctgagcctctgacagtgacggcaccatccctaaccatt
gcagagaacatggccgacctgattgatggatactgccggctggtaaacggagccacacag
tccttcatcatcagaccacagaaagaaggtgaacgggcgttgccatcaataccaaagttg
gccaacagcgaaaagcaaggcatgcggacacatgcagtctctgtgtcaggagtcaatcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccttgaa
cctcctccaaccgatgaaattagtggggacgagacagatgactatgccgagatcatcgat
gaggaagatacatacaccatgccctcgaaaagctatggaatagatgaagccagggattat
gagattcagagggaaagaatagaacttggacgctgtattggagaaggtcagtttggagat
gtacatcaaggcgtgtacctgagcccagagaatccagctttggctgttgcaatcaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaagttccttcaagaagccttaacaatg
cgtcagtttgaccatcctcacatcgtgaagctgattggagtcattacagagaatcctgtc
tggataatcatggagttgtgcacgcttggagagctaaggtcatttttgcaagtaagaaaa
tacagcttggatctggcatctttgatcctatatgcctatcagcttagtacagcactcgcg
tatctggagagcaaaagatttgttcacagggacattgctgctcgaaatgttctggtgtcc
tcaaatgattgtgtaaaattaggagactttggattatcccgatatatggaagacagtact
tactataaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgacgttttacctcagctagtgacgtgtggatgtttggtgtgtgtatgtgggagata
ctgatgcatggcgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaatt
gagaatggggaaagattaccaatgcctccaaattgtcctcccaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcgacccaggtttactgaacttaaagctcag
ctcagcacaatcctggaggaagagaaggttcagcaagaagaacggatgaggatggagtcc
agaagacaggcgaccgtgtcctgggaatctggagggaatgatgaagcaccacctaagccc
agcagacctggttatcctagcccaaggtccagtgaaggattttaccccagcccacagcac
atggtccagaccaatcactaccaggtctctggctacccgggttcccatggaatcccagcc
atggctggcagcatttacccaggtcaggcatctcttctggaccagacagaattgtggaat
cacagacctcaggagatgtccatgtggcagcccaatgtggaggactcagcagctttggac
cttcgagggatgggtcaggtgcttccccctcacctgatggaagagcggctaatccgacag
cagcaggaaatggaagaggaccagcgctggctggagaaggaagagcgatttctgaaacct
gacgtgaggctctctcgaggcagcatcgacagggaggacgggagttttcagggtccgact
ggaaaccaacacatctaccagcctgtggggaaaccagatcctgcagcgccaccaaagaaa
ccaccacgccctggagcacctggccacctaagcaacctggcgagcataggcagccctgca
gacagctacaatgagggtgtcaagccgtggaggcttcagccccaggaaatcagcccccct
cccactgccaacctggaccggtccaatgacaaggtgtatgagaatgtgacgggtctagtg
aaagctgtcatcgagatgtccagcaaaatccagccagctcccccggaggagtacgtccct
atggtgaaggaagtcggcctggctctgcggaccttactggccaccgtggatgagacgatt
cccgccctcccagccagcacacatcgagagatcgagatggcgcagaagctgctgaactcc
gacttgggtgagctcatcagcaagatgaagctggcccagcagtatgtcatgaccagctta
cagcaggagtataagaagcagatgctgacagctgctcatgccctggctgtggacgccaag
aacctccttgatgtaattgatcaagcaagactgaaaatgctagggcaggcgcggccacat
tga
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