Panthera leo (lion): 122199660
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Entry
122199660 CDS
T10741
Symbol
CHEK1
Name
(RefSeq) serine/threonine-protein kinase Chk1
KO
K02216
serine/threonine-protein kinase CHEK1 [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04110
Cell cycle
plez04115
p53 signaling pathway
plez04218
Cellular senescence
plez05166
Human T-cell leukemia virus 1 infection
plez05170
Human immunodeficiency virus 1 infection
plez05203
Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
122199660 (CHEK1)
04115 p53 signaling pathway
122199660 (CHEK1)
04218 Cellular senescence
122199660 (CHEK1)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
122199660 (CHEK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122199660 (CHEK1)
05170 Human immunodeficiency virus 1 infection
122199660 (CHEK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122199660 (CHEK1)
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
plez03400
]
122199660 (CHEK1)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122199660 (CHEK1)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: CAMK group
CAMKL family
122199660 (CHEK1)
DNA repair and recombination proteins [BR:
plez03400
]
Eukaryotic type
Check point factors
Other check point factors
122199660 (CHEK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
122199660
NCBI-ProteinID:
XP_042760847
UniProt:
A0A8C8X3G0
LinkDB
All DBs
Position
D1:22567976..22599371
Genome browser
AA seq
476 aa
AA seq
DB search
MAVPFVEDWDLVQTLGEGAYGEVQLAVNRRTEEAVAVKIVDMKRAIDCPENIKKEICINK
MLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEQDAQRFFHQLMAGVVY
LHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRHNNRERLLNKMCGTLPYVAPELLK
RKEFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLA
LLHKILVENPSVRITIPDIKKDRWYNKPLKKGAKRPRVTSGGISESPSGFSKHIQSNLDF
SPVNSASSEENVKYSSSQPEPRTGLSLWDTSPSYIDKLVQGISFSQPTCPDHMLLNSQLL
GTPGSSQNPWQRLVKRMTRFFTKLDADKSYQCLKETCEKLGYQWKKSCMNQVTVSTTDRR
NNKLIFKVNLVEMDEKILVDFRLSKGDGLEFKRHFLKIKGKLSDVVSSQKVWLPAT
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgccctttgtggaagactgggacttggtgcaaaccctgggagaaggtgcctat
ggagaagttcaacttgctgtgaatagaagaactgaagaagcagttgcagtcaagattgta
gacatgaaacgtgccatagactgtccagaaaatattaagaaggagatctgtatcaataaa
atgttaaatcatgagaatgtagtgaaattctatggccacaggagagaaggcaatatccag
tatctatttctggagtactgtagtggaggagaactttttgaccgaatagagccagacata
ggcatgcctgaacaagatgctcaaaggttcttccatcaactcatggcaggggtggtttat
ctacatggtattgggataactcacagggatattaagccagaaaatctcctattggatgaa
agggataacctcaagatctctgactttggcttggcaacagtgtttcggcataataatcgt
gagcgtttattgaacaagatgtgtggcactttaccttatgttgctccagaacttctaaag
agaaaagaatttcatgcagaaccagttgatgtttggtcctgtggaatagtacttacagca
atgttggctggagaattgccatgggaccagcccagtgacagttgtcaggaatattctgat
tggaaagaaaaaaaaacatacctcaacccttggaaaaaaattgattctgctcctctagct
ttgctgcataaaatcctagttgagaatccatcagtaaggattaccattccagacatcaaa
aaagatagatggtacaacaaacctctcaagaaaggggcaaagaggccccgagtcacttca
ggtggtatatcagagtctcctagtggattttctaagcacattcaatccaatttggacttc
tctccagtgaacagtgcttctagtgaagaaaatgtgaagtactccagttcccaaccagaa
ccacggacaggtctttccttatgggacaccagtccttcatatattgataaactggtacaa
gggatcagtttttcccagcccacatgtcctgatcatatgctcctgaatagtcagttactt
ggcaccccaggatcctcacagaacccttggcaacgcttggttaaaagaatgacacggttt
tttaccaaattggatgcagacaaatcttaccaatgcctgaaagagacttgtgagaaactg
ggctatcaatggaaaaagagctgtatgaatcaggttactgtatcaacaactgataggaga
aacaataaactgattttcaaagtgaatttggtagaaatggatgagaagatcttggttgac
tttcggctatctaagggtgacggattggaattcaagagacacttcctgaagattaaaggg
aaactgagtgatgttgtgagtagccagaaggtttggcttcctgccacatga
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