Panthera leo (lion): 122202043 Help Entry 122202043         CDS       T10741                                  Name (RefSeq) cytochrome P450 2E1   KO K07415   cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-] Organism plez  Panthera leo (lion) Pathway plez00140   Steroid hormone biosynthesis plez00590   Arachidonic acid metabolism plez00591   Linoleic acid metabolism plez00980   Metabolism of xenobiotics by cytochrome P450 plez00982   Drug metabolism - cytochrome P450 plez00983   Drug metabolism - other enzymes plez01100   Metabolic pathways plez04932   Non-alcoholic fatty liver disease plez04936   Alcoholic liver disease plez05204   Chemical carcinogenesis - DNA adducts plez05208   Chemical carcinogenesis - reactive oxygen species Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     122202043    00590 Arachidonic acid metabolism     122202043    00591 Linoleic acid metabolism     122202043   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     122202043    00982 Drug metabolism - cytochrome P450     122202043    00983 Drug metabolism - other enzymes     122202043  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis - DNA adducts     122202043    05208 Chemical carcinogenesis - reactive oxygen species     122202043   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     122202043    04932 Non-alcoholic fatty liver disease     122202043  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:plez00199]     122202043 Cytochrome P450 [BR:plez00199]  Cytochrome P450, animal type   CYP2 family    122202043 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 DUF6361 Motif Other DBs NCBI-GeneID:  122202043 NCBI-ProteinID:  XP_042764119 LinkDB All DBs Position D2:87251447..87260555 Genome browser AA seq 495 aa AA seqDB search MAALGITVALLVWMATLMLISVWKQIYSSWKLPPGPFPLPIIGNLLQLDFKNVPKSLTKL AERYGPVFTLYLGSQRTVVLHGYKAVKEVLLDYKNEFSGRGEIYAFAAHKEKGITFNNGP SWKDTRRLSLSILRDYGMGKLANEERIQREVPFLMEAFRKTQGQPFDPTFVLGYAPCNVI SDILFHKRFDYTDQTGLRIQKLFNENFHLLSTSWLQLYNIFPSYMRYLPGNHRKVIKNVY EIKSYTAARVKEHEESLDPNCPRDFTDSLLLEMRKERYTKEPWFTFDNIAATVADLFFAG TETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAFKDRLEMPYMDAVVHEIQRF IDLLPSNLPHEAIQDTMFRGYVIPKGTVVVPTLDSLLFDNQEFPDPEKFMPEHFLNESGK FKYSDYFKVFSAGKRVCVGEGLARMELFLFLSAILQHFNLKPLVDPKDIDLSPSTIGFAK IPPRYKLCVIPRSGV NT seq 1488 nt NT seq  +upstreamnt  +downstreamnt atggctgccctgggcatcacagttgccctgttggtgtggatggccaccctaatgcttatc tctgtctggaagcagatctacagcagctggaaactaccccctggccctttcccactgccc attattgggaatcttctccagttggatttcaagaatgttcccaaatctttaaccaagttg gcagagcggtacgggcctgtgttcaccttgtacctgggctcccagcgcaccgtggttctg catggctataaggcagtgaaggaagtcctgctcgactacaagaatgaattttctggcaga ggagaaatctatgcctttgcggcacacaaggaaaaaggaattacgttcaacaatgggccg agctggaaggacacccggcgcctgtctctgagcatcctccgggactatggcatggggaag cttgccaatgaggagcggatccagagggaggtgcccttcctgatggaggcattccggaag acccagggacagcccttcgaccccacctttgttctgggctacgccccctgcaacgtcatc tcggacatcctcttccacaagcgctttgactacacggaccaaaccgggctgaggatacag aagctgttcaacgagaacttccacctgctcagcaccagctggctccaattatataacatt ttcccaagctatatgcgctacctgcctggaaaccatagaaaagtaataaaaaatgtgtat gaaataaaaagttatactgcagcaagagtgaaggagcacgaggagtcgctggaccccaac tgcccccgggacttcaccgacagcctgctcctggagatgcggaaggaaagatacaccaaa gagccttggttcacctttgacaacattgctgccaccgtagctgacctgttttttgcgggt acagagaccaccagcaccactctgagatatgggctcctgattctcatgaaatacccagag atcgaagagaaactgcatgaagaaatcgacagggtgattgggccaagccgaatccctgcc ttcaaggaccggttagagatgccttatatggatgccgtggtgcatgagattcagcgattc atcgacctcttgccctccaacctgccccatgaagcaatccaggacacaatgttcagagga tacgtcatccccaagggtacagtcgtggtcccaacgctggactccctcttgtttgacaac caagagttccctgatccagagaagtttatgccagagcactttctgaatgaaagtggaaag ttcaaatatagtgattatttcaaggtattttctgcaggaaagcgggtgtgtgttggagaa ggcctggctcgcatggagttgttcctgttcttgtccgccattttgcagcactttaacctg aagcctctcgttgaccccaaggatatcgatctcagtcccagcacaattgggtttgccaaa atcccaccccgttacaagctctgtgtcattccccgttcgggtgtgtga

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