Panthera leo (lion): 122202493 Help Entry 122202493         CDS       T10741                                  Symbol HKDC1 Name (RefSeq) hexokinase HKDC1   KO K00844   hexokinase [EC:2.7.1.1] Organism plez  Panthera leo (lion) Pathway plez00010   Glycolysis / Gluconeogenesis plez00051   Fructose and mannose metabolism plez00052   Galactose metabolism plez00500   Starch and sucrose metabolism plez00520   Amino sugar and nucleotide sugar metabolism plez00524   Neomycin, kanamycin and gentamicin biosynthesis plez01100   Metabolic pathways plez01200   Carbon metabolism plez01250   Biosynthesis of nucleotide sugars plez04066   HIF-1 signaling pathway plez04910   Insulin signaling pathway plez04930   Type II diabetes mellitus plez04973   Carbohydrate digestion and absorption plez05230   Central carbon metabolism in cancer Module plez_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate plez_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc plez_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     122202493 (HKDC1)    00051 Fructose and mannose metabolism     122202493 (HKDC1)    00052 Galactose metabolism     122202493 (HKDC1)    00500 Starch and sucrose metabolism     122202493 (HKDC1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     122202493 (HKDC1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     122202493 (HKDC1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     122202493 (HKDC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     122202493 (HKDC1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     122202493 (HKDC1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     122202493 (HKDC1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     122202493 (HKDC1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:plez04131]     122202493 (HKDC1) Enzymes [BR:plez01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      122202493 (HKDC1) Membrane trafficking [BR:plez04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     122202493 (HKDC1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  122202493 NCBI-ProteinID:  XP_042764813 UniProt:  A0A8C8XU72 LinkDB All DBs Position D2:29792541..29841368 Genome browser AA seq 917 aa AA seqDB search MFAVHLMAFYFTKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQAEMQKGLGKDTNPTAS VKMLPTFVRAIPDGSEKGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIR GNGSELFEYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV QDTDVVDCLAKAIKKHKDIDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKAGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLVRLRTTVGMDGTVYKIH PQYPKRLHKVVRKLVPNCDVRFLLSESGSTKGAAMVTAVASRVQTQRKQIDKVLALFQLT QEQLKAVQGKMRTEFEYGLKRDTHLLATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGT MMTCGYEDPNCEIGLIAGTGSNMCYMEEMKNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDKKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKHGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLYGAGLAAI VEKRREDQGLENLKVTVGVDGTLYKLHPHFSRILQETVKELAPRCDVTLMLSEDGSGKGA ALITAVAKRLQQAQKEK NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgccgtacacttgatggcattttacttcaccaagctgaaggaggatcagatcaag aaggtggacagattcctgtatcacatgcggctctccgatgagacccttttggacatcatg gctcggttccaggctgaaatgcagaagggcctggggaaggacaccaaccccacagcctcc gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaaaggggagttt ctttccctggatcttggagggtccaagtttcgagtcttgaaggtgcaggtctctgaagag gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga ggaaacggctcagagctgtttgaatacgtagctgactgtctggcagacttcatgaagacc aaagggttgaagcataagaaattgccccttggcctaaccttttcttttccctgcagacag actaaactggaagagggcatcctgctttcatggaccaagaagtttaaggcacgtggagtt caagacactgatgtggtggattgtctggccaaagctataaaaaaacacaaggacatagac gtggacatcctggccttggtcaatgacaccgtggggaccatgatgacgtgcgcctatgat gatccctactgtgaagttggtgtcatcattggcactggcaccaacgcgtgctacatggag gacatgagcaacattgacctggtggaaggcgacgagggcaggatgtgcatcaacacggag tggggggcctttggggacgacggggctctggaagacatccgcaccgagttcgaccgggag ctggaccttggctctctcaaccctgggaagcagctgtttgagaagatgatcagcggcctg tacctgggtgaacttgttaggatcatcttgctgaagatggccaaggcaggcctcctgttt ggcggcaagaaatcctctgctctccacactaagggcaagattgaaacacggcatgtggct gccatggagaagtataaagaaggcctggccaatacaagagagatcctgacagatctgggc ctggagccttcggaggccgactgcatcgcagttcagcacgtctgcaccatcgtgtccttc cgttcagccaatctctgtgcagcggccctggcagccatcctgacacgcctccgggagaac aagaagctggtgcggctccggaccaccgtgggcatggatggcacggtctacaagatacat cctcaatacccaaaacgcctgcacaaggtggtgaggaaactggttccgaactgtgatgtc cgcttcctcttgtcggagagtggaagcaccaagggggctgccatggtgacagcggtggcc tcccgtgtgcagacccaacggaagcagattgacaaggtgctggctttgttccagctgact caagagcaacttaaggctgtgcagggcaagatgcggactgaattcgagtacgggctgaaa agagacacccacctgctggccacggtcaagatgctgcccacctacgtttgcgggatgcca gatggtacagagaaaggcaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagtggacggaggtcggtgcgaatgtacaacaagatcttcgcc atccccttggagatcatgcagggcaccggcgaggagctgtttgaccacattgtgcagtgc atcgctgacttcctggactacatgggcctcaagggagcccagctgcccctgggcttcaca ttctcatttccctgcaggcagacgagcattgacaagggaacactcattgagtggaccaaa ggcttcaaggccactgactgtgaaggggaagatgtggtggacatgctcagggaagccatc aagaggagaaatgagtttgacctggacatagttgcgatcgtgaatgacacagtggggact atgatgacctgtggatatgaagatcctaattgtgagattggcctgattgcaggaacaggc agcaacatgtgctacatggaggagatgaagaacatcgagctggtggaaggagacgaaggg aagatgtgcattaacaccgagtggggagggtttggagataatggctgcatagatgacatc cggacgcaatatgacaagaaggtggatgaggggtctttgaaccctggcaaacagagatat gagaaaatgaccagtgggatgtacctgggggagattgtgcggcagatcctgattgacctc accaagcacggtctccttttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaagttcctgtcccagattgaaagcgatcggctggccctcctccaggtcagg aggatcctgcagcagcttggcctggacagcacgtgtgaggacagcattgtggtgaaggag gtgtgtggagctgtgtcccggcgggcagcccagctctatggcgctggcctggcagccatc gtggagaagaggagggaagaccaggggcttgagaacctgaaggtcaccgtgggtgtggat ggcaccctgtacaagctgcaccctcacttttctcggatattgcaggaaaccgtgaaagaa ctagctcctcgatgtgatgtgacactcatgctgtcagaagatgggagtggaaagggagct gctctgatcactgctgtggccaagaggttacagcaggcacagaaggagaaatag

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