Panthera leo (lion): 122202669
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Entry
122202669 CDS
T10741
Symbol
IDE
Name
(RefSeq) insulin-degrading enzyme isoform X1
KO
K01408
insulysin [EC:
3.4.24.56
]
Organism
plez Panthera leo (lion)
Pathway
plez03266
Virion - Herpesvirus
plez05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
122202669 (IDE)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122202669 (IDE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122202669 (IDE)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.56 insulysin
122202669 (IDE)
Peptidases and inhibitors [BR:
plez01002
]
Metallo peptidases
Family M16: pitrilysin family
122202669 (IDE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
PqqF-like_C_4
Tn916-Xis
PqqF_C_3
Motif
Other DBs
NCBI-GeneID:
122202669
NCBI-ProteinID:
XP_042765041
UniProt:
A0A8C9D864
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All DBs
Position
D2:complement(52238808..52433840)
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AA seq
1019 aa
AA seq
DB search
MRYRLAWLLHSARPSTFRSVVGARLPPPERLCGFQEKTYSKMNNPAIKRLGNHIIKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
LLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
VSKSFEGKTDRTEEWYGTQYKQEAVPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILSL
EKEATPYPSLIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELL
KDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgcggtaccggttagcgtggctgctgcactccgcgcggcccagcaccttccgctccgtc
gtcggcgcccgcctgccgcccccggagcgcctctgtggcttccaagaaaagacttacagc
aagatgaataatccagctatcaagagactaggaaatcacattatcaaatctcctgaagac
aagcgagaataccgtggattagagctggccaatggtatcaaagtacttcttatcagtgat
ccgaccacggataagtcatcggcagcacttgatgtacacataggttcattgtcagatcct
ccaaatattgctggcttaagtcatttttgtgaacatatgctatttttgggaacaaagaaa
taccctaaagaaaatgaatacagccagtttcttagtgagcatgcaggaagttcaaatgcc
tttactagtggagaacataccaattactattttgatgtttcccatgaacacctagaaggt
gccctagacaggtttgcacagtttttcctgtgccccttgtttgatgagagttgcaaagac
agagaggtgaatgcagttgattcagaacatgagaagaatgtgatgaatgatgcctggaga
ctctttcagttggaaaaagctacggggaatcccaaacaccccttcagcaaatttgggaca
ggaaacaaatatactttggagactagaccaaaccaagaaggcattgatgtaaggcaagaa
ctactgaaattccattctacttattattcatcaaacttgatggcaatttgtgtgttaggt
cgagaatctttagatgacctgactaatctggtggtaaagttattttctgaagtagagaac
aaaaatgtcccattgccagaatttcctgaacaccctttccaagaagaacatcttaaacaa
ctttacaaaatagtacccattaaggatattaggaatctttatgtgacatttcccatacct
gaccttcagaaatactacaagtcaaatcctggccattatcttggtcatctcattgggcat
gaaggtcctggaagtctgttatcagaacttaaatcaaagggctgggtaaatactcttgtt
ggtgggcaaaaggaaggagcccgaggttttatgttttttatcattaatgtggacttgact
gaggaaggattattacatgttgaagatataattttgcacatgtttcaatacattcagaag
ttacgtgcagaaggacctcaagaatgggttttccaagagtgcaaggacttgaatgctgtt
gcattccggtttaaagataaagagaggccacggggctatacctctaagattgcaggaata
ttgcattattatcccctagaagaagtgcttacagctgaatatttactggaagaatttaga
cctgacttaatagagatggttcttgataagctcagaccagaaaatgtccgggttgcgata
gtttccaagtcttttgaaggaaaaactgatcgcacggaagagtggtatggaacccagtac
aagcaagaagctgtaccagacgaagtcattaagaaatggcaaaatgctgacctgaatgga
aaatttaaacttccaacgaagaatgaatttattcctacgaattttgagattttatcatta
gaaaaagaagcaacaccatacccttctcttattaaggatacagctatgagcaaactctgg
ttcaaacaagatgataagtttttcttgccaaaggcttgtctcaactttgaatttttcagc
ccatttgcttatgtggaccccttgcactgtaacatggcctatttgtaccttgagctcctc
aaagactccctcaacgagtatgcatatgcagcagagctagcaggcttgagctatgacctc
caaaataccatctatgggatgtatctctcggtgaaaggttacaatgacaagcagccgatt
ttgctaaagaagattattgagaaaatggctacctttgagattgatgaaaaaagatttgaa
attatcaaagaggcgtacatgcgatctcttaacaatttccgagctgagcagcctcaccag
catgccatgtactacctccgcttgctgatgactgaagtggcctggactaaagatgaatta
aaagaagccctggatgatgtcacccttcctcgccttaaggccttcatacctcagctcctg
tcacggctgcacattgaagcccttctccatggaaacataacaaagcaggctgcactagga
atcatgcagatggttgaagacacccttattgaacatgctcatacgaaacctctccttcca
agtcagctggttcggtatagagaagttcagcttcctgacagaggatggtttgtgtatcag
cagaggaatgaagttcacaataactgtggcatcgagatatactatcagacagacatgcag
agcacctcagagaatatgtttctagagctcttctgtcagatcatctctgagccttgcttc
aacaccctgcgcaccaaggagcagctgggctatatcgtcttcagcgggcctcgtcgagcc
aacggcatacagggcttacgattcatcatccagtcagaaaagcctcctcactacctagaa
agccgagtggaagctttcttaatcaccatggagaagtccatagaggacatgacagaagag
gcttttcaaaaacacattcaagcattagcaattcgtcgactagacaaaccaaagaaactg
tccgcagagtgtgctaaatattggggggaaatcatctcccagcaatacaatttcgacaga
gataacatagaagttgcatatttaaagacacttaccaaggaagatatcatcaaattctac
aaggaaatgttggcagtagatgccccaaggagacataaagtatccgtccatgttcttgcc
agggaaatggattcctgtcctgtcgttggagagttcccatgtcaaaatgatataaatttg
tcacaagcaccagccttgccacaacctgaagtgattcagaacatgaccgagttcaagcgt
ggtttgccactgtttccccttgtgaaaccacatattaacttcatggctgcaaaactctga
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