KEGG   Panthera leo (lion): 122203681
Entry
122203681         CDS       T10741                                 
Symbol
ORAI1
Name
(RefSeq) calcium release-activated calcium channel protein 1
  KO
K16056  calcium release-activated calcium channel protein 1
Organism
plez  Panthera leo (lion)
Pathway
plez04020  Calcium signaling pathway
plez04024  cAMP signaling pathway
plez04611  Platelet activation
plez04924  Renin secretion
plez04925  Aldosterone synthesis and secretion
plez04927  Cortisol synthesis and secretion
plez04934  Cushing syndrome
plez05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    122203681 (ORAI1)
   04024 cAMP signaling pathway
    122203681 (ORAI1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122203681 (ORAI1)
  09152 Endocrine system
   04924 Renin secretion
    122203681 (ORAI1)
   04925 Aldosterone synthesis and secretion
    122203681 (ORAI1)
   04927 Cortisol synthesis and secretion
    122203681 (ORAI1)
 09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    122203681 (ORAI1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    122203681 (ORAI1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:plez04040]
    122203681 (ORAI1)
Ion channels [BR:plez04040]
 Other channels
  Calcium channel, calcium release-activated (Orai)
   122203681 (ORAI1)
SSDB
Motif
Pfam: Orai-1 TMEM190 m04gp34like DUF4153
Other DBs
NCBI-GeneID: 122203681
NCBI-ProteinID: XP_042766613
LinkDB
Position
D3:complement(7674667..7688837)
AA seq 301 aa
MHPEPAPPPDNNSPELPLSGGSTTSGSRRSRRRSGDGETPGSSPPPAAVTYPDWIGQSYS
EVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDADHDYPPGLLI
AFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTV
IGTLLFLAEVVLLCWVKFLPLKKQPGQLRPTSKSPASDAVANVSSTGGITPGQAAAIAST
TIMVPFGLVFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHY
A
NT seq 906 nt   +upstreamnt  +downstreamnt
atgcatccggagcccgccccgcccccggacaacaacagccccgagcttcccctcagcggc
ggcagcaccaccagcggcagccgccggagccgccgccgcagcggggacggggagaccccg
gggtcgtcgccgccgccagccgccgtcacctacccggactggatcggccagagttactcc
gaggtgatgagcctcaacgagcactcgatgcaggcgctgtcctggcgcaagctttacttg
agccgtgccaagctcaaagcctctagccggacctctgctctgctctccggcttcgccatg
gtggcgatggtggaggtgcagctagatgccgaccatgactaccctcccgggctgctcatc
gcctttagtgcatgcaccacggtgctggtggccgtgcacctgtttgcacttatgatcagc
acctgcatcctgcccaacatcgaggcggtgagcaacgtgcataacctcaactcggtcaag
gagtcaccccatgagcgcatgcaccgccacatcgagctggcctgggccttttccacggtc
atcggcacgctgctcttcctggctgaagtggtgctgctctgctgggtcaagttcttgcct
ctcaagaagcagcccgggcagctgcggcccaccagcaagtccccggccagcgatgcagtc
gccaacgtcagcagcactggtggcatcactccgggccaagccgccgccatcgcctccacc
accatcatggtcccttttggcctggtcttcatcgtctttgccgtccacttctaccgctca
ttggtcagccataagacggaccgacagttccaggagctcaacgagctggccgagttcgcc
cgcttgcaggaccagctggaccacagaggggatcaccccctgacgcccggcagccactat
gcataa

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