Panthera leo (lion): 122204960 Help Entry 122204960         CDS       T10741                                  Symbol SHC3 Name (RefSeq) SHC-transforming protein 3   KO K17448   SHC-transforming protein 3 Organism plez  Panthera leo (lion) Pathway plez01521   EGFR tyrosine kinase inhibitor resistance plez01522   Endocrine resistance plez04012   ErbB signaling pathway plez04014   Ras signaling pathway plez04062   Chemokine signaling pathway plez04072   Phospholipase D signaling pathway plez04510   Focal adhesion plez04650   Natural killer cell mediated cytotoxicity plez04722   Neurotrophin signaling pathway plez04910   Insulin signaling pathway plez04915   Estrogen signaling pathway plez04917   Prolactin signaling pathway plez04926   Relaxin signaling pathway plez04935   Growth hormone synthesis, secretion and action plez05034   Alcoholism plez05100   Bacterial invasion of epithelial cells plez05214   Glioma plez05220   Chronic myeloid leukemia plez05224   Breast cancer plez05225   Hepatocellular carcinoma plez05226   Gastric cancer Brite KEGG Orthology (KO) [BR:plez00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     122204960 (SHC3)    04014 Ras signaling pathway     122204960 (SHC3)    04072 Phospholipase D signaling pathway     122204960 (SHC3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     122204960 (SHC3)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     122204960 (SHC3)    04062 Chemokine signaling pathway     122204960 (SHC3)   09152 Endocrine system    04910 Insulin signaling pathway     122204960 (SHC3)    04915 Estrogen signaling pathway     122204960 (SHC3)    04917 Prolactin signaling pathway     122204960 (SHC3)    04926 Relaxin signaling pathway     122204960 (SHC3)    04935 Growth hormone synthesis, secretion and action     122204960 (SHC3)   09156 Nervous system    04722 Neurotrophin signaling pathway     122204960 (SHC3)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     122204960 (SHC3)    05226 Gastric cancer     122204960 (SHC3)    05214 Glioma     122204960 (SHC3)    05220 Chronic myeloid leukemia     122204960 (SHC3)    05224 Breast cancer     122204960 (SHC3)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     122204960 (SHC3)   09165 Substance dependence    05034 Alcoholism     122204960 (SHC3)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     122204960 (SHC3)    01522 Endocrine resistance     122204960 (SHC3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PID SH2 DUF7063 DUF7145 Motif Other DBs NCBI-GeneID:  122204960 NCBI-ProteinID:  XP_042768775 LinkDB All DBs Position D4:complement(2901597..3002950) Genome browser AA seq 587 aa AA seqDB search MLPRTKYNRFRNDSVTSVDDLLHNLSVSGGGKVSAARAAPAAAPYLVSGDALRRAPDDGP GSLGHLLHKVSHLKLSSSGLRGRSAARARAGARLSGSCSAPSLAAPDGSAPPGPGAPAMR AARKGRPGDQPPPRAPHASDQVLGAGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAIS RVCEAVPGAKGAFRKRKPPSKMLSSILGKSNLQFAGMNISLTVSTASLNLRTPDSKQIIA NHHMQSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQAFELRFK QYLQCPSKVPAFHDRMQSLDEPWTEEEGDGSDHPYYNSIPSKAPPPGGFVDVRLQARPHA PDAAQFAGKEQTYYQGRHLGEPFGEDWKQAPVRQGSLDTYSLPEGRAHAGPGEAPTYVNA QHIPPQATPASGSSAESSPRKDLFDMKPFEDALRNQSSGPVLSKAASVECISPVTPRAPD AKMLAELEGEPWYQGEMSRKEAEGLLKNDGDFLVRKSATNPGSFVLTGMHNGQAKHLLLV DPEGTVRTKDRVFDSISHLINHHLENSLPIVSAGSELCLQQPVEKPL NT seq 1764 nt NT seq  +upstreamnt  +downstreamnt atgcttccacgcaccaagtacaaccgcttcaggaatgactcggtgacatcggtcgacgac cttctgcacaacctgtcggtgagcggcggcggcaaggtctcggcggcgcgcgcggccccg gcggcggccccctacctcgtgtccggagacgcgctgcgcagggcgcccgacgatgggccg ggcagcctgggccacctgctccacaaggtgtcccacctgaaactctccagctcgggcctc cgcggccgctcggcggccagggcgcgggcgggcgcgcggctctcgggcagctgcagcgcg cccagcctggccgccccggacggcagcgcgccccccggccccggcgccccggccatgcgc gccgccaggaagggccggcccggcgaccagccgccgccgcgcgccccgcacgccagcgac caggtgctgggggccggagtcacctacgtcgtcaagtacttggggtgcattgaagttctc cgctcaatgaggtctcttgacttcagtacaagaacacagattaccagggaagccatcagc cgtgtctgcgaagccgtccctggcgccaagggagccttcaggaagagaaagcctcccagc aaaatgctgtccagcatcttgggcaagagcaacctccagtttgcgggcatgaacatctcc ctgaccgtgtccaccgccagcctgaacctgcggacgcccgactccaaacagatcatcgcc aaccaccacatgcagtccatctcgttcgcctccgggggagacccggacacaaccgactac gttgcgtacgtagctaaggaccctgttaaccgcagagcgtgtcacattctggagtgctgc gacgggctggcccaggatgtcatcggctccatcggacaggcctttgaactccgctttaag cagtatttgcagtgtccttccaaggtccccgctttccatgaccgaatgcagagtctggac gagccttggactgaagaggagggggatggctcagaccacccgtactacaacagcatccca agcaaggcgccccctccggggggctttgtggacgtgcggctgcaagccagaccccatgcc cctgacgcggcccagtttgcaggcaaagagcagacgtactaccaggggagacacctggga gagccgttcggcgaagactggaagcaagcacctgtccggcaagggtccttggacacctac agcctgccggaagggagagctcacgcgggccccggagaagcccccacctacgtgaacgcc cagcacatcccgccgcaggccacgccggcctccggcagcagcgcggagagcagcccgcgg aaagacctcttcgacatgaaaccctttgaagacgctctcaggaaccagtcctcggggcct gtgctgagcaaggcggcctccgtggagtgcatcagccctgtcacgcccagagcccccgat gccaagatgctggcggagctggaaggggagccttggtaccaaggggagatgagccggaag gaggctgaggggctgctgaagaacgacggggacttcctggtcaggaagagcgccaccaac ccgggctccttcgtcctcactggcatgcacaacggccaggccaagcacctgctgctcgtg gacccagagggcacggtccggacgaaggacagggtcttcgacagcatcagccacctcatc aaccaccacctggagaacagcctgcccatcgtctctgctggaagcgagctctgtctccag cagccggtggagaagcccctgtga

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