Panthera leo (lion): 122205274
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Entry
122205274 CDS
T10741
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1 isoform X1
KO
K08041
adenylate cyclase 1 [EC:
4.6.1.1
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
plez01522
Endocrine resistance
plez04015
Rap1 signaling pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04062
Chemokine signaling pathway
plez04072
Phospholipase D signaling pathway
plez04081
Hormone signaling
plez04082
Neuroactive ligand signaling
plez04114
Oocyte meiosis
plez04211
Longevity regulating pathway
plez04213
Longevity regulating pathway - multiple species
plez04261
Adrenergic signaling in cardiomyocytes
plez04270
Vascular smooth muscle contraction
plez04371
Apelin signaling pathway
plez04540
Gap junction
plez04611
Platelet activation
plez04713
Circadian entrainment
plez04714
Thermogenesis
plez04720
Long-term potentiation
plez04723
Retrograde endocannabinoid signaling
plez04724
Glutamatergic synapse
plez04725
Cholinergic synapse
plez04727
GABAergic synapse
plez04750
Inflammatory mediator regulation of TRP channels
plez04911
Insulin secretion
plez04912
GnRH signaling pathway
plez04913
Ovarian steroidogenesis
plez04914
Progesterone-mediated oocyte maturation
plez04915
Estrogen signaling pathway
plez04916
Melanogenesis
plez04918
Thyroid hormone synthesis
plez04921
Oxytocin signaling pathway
plez04923
Regulation of lipolysis in adipocytes
plez04925
Aldosterone synthesis and secretion
plez04926
Relaxin signaling pathway
plez04927
Cortisol synthesis and secretion
plez04928
Parathyroid hormone synthesis, secretion and action
plez04934
Cushing syndrome
plez04935
Growth hormone synthesis, secretion and action
plez04970
Salivary secretion
plez04971
Gastric acid secretion
plez04972
Pancreatic secretion
plez04976
Bile secretion
plez05032
Morphine addiction
plez05142
Chagas disease
plez05146
Amoebiasis
plez05163
Human cytomegalovirus infection
plez05166
Human T-cell leukemia virus 1 infection
plez05200
Pathways in cancer
plez05207
Chemical carcinogenesis - receptor activation
plez05414
Dilated cardiomyopathy
Brite
Enzymes [BR:
plez01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
122205274 (ADCY1)
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NCBI-GeneID:
122205274
NCBI-ProteinID:
XP_042769444
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Position
A2:61085380..61192320
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AA seq
1132 aa
AA seq
DB search
MAGAPRGRGGGGGGGGGGAGEPGGAERAARPGGRRGLRACDEEFACPELEALFRGYTLRL
EQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSLQV
PQLQQVGQLALLFSLTFALLCCPFALGRPAGTLAGAASGPATADQGVWQLLLVTFVSYAL
LPVRSLLAIGFGLVVAASHLVVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRILAE
RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI
QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC
VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY
DVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFI
VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVLTCEDDDKR
RALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQTELEMADLDFFTLKYKQAE
RERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCICFLVACVLYLH
VTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNGSLVVLTPSGRN
AVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAP
GGGVASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKR
ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLR
LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFA
IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ
GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGR
AGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHGQHLPPGAAGKEA
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggcgggggcgccgcgcggccgaggcggaggcggcggcggaggcggaggcggcgcgggc
gagcccgggggcgcggagcgggcggcccggccgggcggccggcgcgggctgcgggcgtgc
gacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg
gagcaggcggctacgctgaaggcgctggcggtgctcagcgggctggcgggcgcgctggcg
ctggccgagctgctgggcgcgccggggcccgcggccggcctggcccggggctcgcacccc
gcgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtgcgctcgctgcaggtg
ccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctg
tgctgccccttcgcgctcggccgccccgcggggaccctcgccggcgccgcttcggggccg
gcgaccgccgaccagggcgtgtggcagctcctgctggtcaccttcgtgtcctatgccctg
ctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttg
gtggtcacggccaccttggtacccgccaagcgcccgcgtctctggaggacgcttggtgcc
aacgccctgctcttcctcagcgtgaacatgtatggggtgtttgtgcgcatcctggccgag
cgctcccagcggaaagccttcctgcaagcccggaactgcatcgaagatcggctgaggctg
gaggatgagaacgagaagcaggaacggctgctcatgagccttctgccccggaatgttgcc
atggagatgaaggaggacttcttgaagccccccgagaggattttccacaagatttacatc
cagcggcatgacaacgtgagcatcctctttgcggacattgtgggcttcacgggcctggcg
tcgcagtgcacggcacaggagctggtcaagctcctcaacgagctgttcggcaagtttgat
gaactggccacggagaatcactgtcgccgcatcaagatcctaggggactgttactactgt
gtgtccggcctcacccagcccaagaccgaccacgcccactgctgtgtggagatgggcctg
gacatgatcgacaccatcacgtctgtggccgaggccactgaggtggacctgaacatgcgc
gtggggctgcacacaggcagggtcctctgcggggtcctgggcctgcgcaagtggcagtac
gatgtgtggtccaatgacgtgaccctggccaacgtcatggaggcggctggcctacctggg
aaggtccacatcacgaagacgaccctggcgtgcctgaacggggactacgaggtggagcca
ggtcacggacatgagaggaacagttttctgaaagctcacaacatcgagaccttcttcatc
gtgccgtcacatcggcggaagatatttccagggctgatcctctctgacataaaaccagcc
aagaggatgaagttcaagaccgtgtgctacctgctcgtgcagctgatgcactgtcggaag
atgttcaaagcagagatcccgttctctaatgtcctgacgtgtgaggacgatgacaagcgg
agggcgctgagaaccgcgtcggagaaactgcgaaaccgctcgtcgttctccgcaaatgct
gtctacaccaccccgggcacgcgcgtcaacaggtacatcggccgcctcctggaagcgcgc
cagacggagctggagatggcggacctggacttcttcactctcaagtacaagcaggctgag
cgggagcgcaagtaccaccagctccaggacgagtattttaccagcgccgtcgttctggcc
ctcgtcctggccgccttgttcggcctcgtctacctgctcatcatcccacagaacctggtc
ctcctgctgctgctggccttctgtatctgcttcctggtggcctgcgtcctgtacctgcac
gtcacccgggtccagtgttttccagggtgcctgacgattcagatccgcaccgtcttgtgt
atcttcgtcgtggtcttaatctactccgtggcccaaggatgtgtggtgggctgcctgccc
tggtcctggagctccacccccaacgggtccctggtggtcctgacacccagcggccgcaac
gccgtgctgcctgccgcgccctgtgagtcggcgccccacgccctgctctgcggccttgtg
ggtaccctcccgctggccgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctc
tttgtgctcacgacgtcctacatcctggtcctggagctcagcggctacaccagggccccc
gggggcggcgtggcgtcggggcgcagtttcgagccgatcatggccatcctgctgttttcc
tgcaccctggccctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgg
gcggcacaggcagaggaggagagagacgacatggagagggtgaagttggataacaagagg
attctcttcaacctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgc
aacatggacctgtactaccagtcctactcacaggtgggcgtcatgtttgcttccatcccc
aacttcgacgacttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgt
ctcctgaacgagatcatcgcagacttcgacgagctcatggacaaagacttttacaaggac
ttggagaagatcaagaccatcgggagcacctacatggccgctgtggggctggcgcctacc
actgggaccaaggccaagaagggcatctcctcccacctgagcacactggccgacttcgcc
atcgagatgttcgacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctc
cgtgtgggcatcaacgtgggccctgtggtggccggggtgattggggctcggaggccgcag
tacgacatctgggggaacacggtcaacgtggccagtcggatggacagcaccggcgtccag
ggcagaatccaggtgactgaggaggttcaccggctgctgcgccgggggacctaccgcttc
gtgtgccgcgggaaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaa
ggcaggacggacggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcga
gccggcctccagggcagactgggcacgggcccgcccccggtgtcctccatggccggcctc
ccggtcagagctgggatgggggctctgcagggctcagggctccccccctgcccccatggc
cagcacctgccccccggagcagctgggaaggaggcttag
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