Panthera leo (lion): 122206187 Help Entry 122206187         CDS       T10741                                  Symbol FASN Name (RefSeq) fatty acid synthase isoform X1   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism plez  Panthera leo (lion) Pathway plez00061   Fatty acid biosynthesis plez01100   Metabolic pathways plez01212   Fatty acid metabolism plez04152   AMPK signaling pathway plez04910   Insulin signaling pathway plez04936   Alcoholic liver disease Module plez_M00082   Fatty acid biosynthesis, initiation plez_M00083   Fatty acid biosynthesis, elongation Brite Enzymes [BR:plez01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      122206187 (FASN) Lipid biosynthesis proteins [BR:plez01004]  Fatty acid synthase   Animal type    122206187 (FASN) Exosome [BR:plez04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    122206187 (FASN)   Exosomal proteins of breast milk    122206187 (FASN)   Exosomal proteins of colorectal cancer cells    122206187 (FASN)   Exosomal proteins of bladder cancer cells    122206187 (FASN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  122206187 NCBI-ProteinID:  XP_042771035 LinkDB All DBs Position E1:complement(60392636..60411066) Genome browser AA seq 2647 aa AA seqDB search MGGGWSPQARAPEVPGQCQRPEGPVVPVKSRGWLDQCGLPHAPEASVLASPGRRSWPPGS WSHRSQTRRWCCGVRKPGERLQPGGLAAGYDQRQAPTLLPLHRAAMEDVVIAGMSGKLPE SENMEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKFDASFFGVHPKQAHTM DPQLRLLLEVTYEAILDGGINPATLRGTHTGVWVGVSGSEASEALSRDPETLLGYSMVGC QRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRRGECPAAIVGGLNILLKPN TSVQFMKLGMLSPDGTCKAFDESGDGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDG CKEQGVTFPSGEAQEQLIRSLYEPAGLSPESLEYIEAHGTGTKVGDPQELNGIAQVLCPS RQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFRSPNTKIPALQDGRLQ VVQQPLPVRGGNVCINSFGFGGSNVHVILQPNPRLPSAPTRHASLPRLLRASGRTPEAVH CLLEQGHRHSQDLAFVSMLNDIAAIPPTAMPFRGYTVLGGKGGSQEVQQVAAGKRPLWFI CSGMGTQWCGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSELLLSTDEATFDDIVHAFVS LTAIQIALIDLLNSMGLRPDGIIGHSLGEVACGYADGCLSQEEAILAAYWRGQCIKETNI PPGTMAAIGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAEVAAFVAELKQEGVFAKEV RTGGMAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQGSLARTFSAEYN VNNLVSPVLFQEALWHVPGDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDQRDNLEF FLSNVGKLHLLGFDVNPNGLLPPMEFPVPRGTPLISPHIKWDHSQTWDVPTAKDFPSGSS GSSASTVCNISVSPESPDHYLVDHCIDGRVLFPATGYLCLVWKTLARTLSQNMEQVPVVF EDVTLHQATVLPKTGTVPLEVRLLQASRTFEVSENGNLIVSGKVYQWEDPDAKLFDSRDG PDTTDPTATFRLSQRDVYKELRLRGYDYGPHFQGILEANLEGNAGRLLWKNNWVTFLDAM LQTSILGLAQCGLRLPTRITSVRIDPATHQRRVYSLLGGAQAVNVVVNSCLNSTVAGGVL ISGLHASMAPRRQQEQFAPILEKFCFTPHTEEGLLAGDTALQEGLQLCRGLARALQTKVA QQGLKMVVSGLDGAQAPQEPPKQGLPRLLAAACQLQLNGGLQLELGQLLAQQRPLLQDDP LLSGLLASPALKACVDTALENMPSLKMKVVEVLAGDGHLYSHIPALLNTQPTLQLEYTAT DRHPQALEAVQAKLQQHGIAQGQWDPADPAPGSLGSADLLLCNCAVASLGDPATAVGNMG AALKEGGFLLLHALLKGHPLGETVAFLTCPEPRRGQQSLLSQDEWESLFAGASLHLVALK RSFYGSVLFLCRRPVLQDSPVFLPVEDPGFQWVNSLKNILADSSQQPVWLTATSCPDSGV VGLVNCLRREPGGHRIRCILVSNLSSTSRTPSLDPGSSELQKVLRGDLVMNVYRDGAWGA FRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQLTGPGVQLCAVHYASLNF RDIMLATGKLSPDAIPGTGRVPRHSQAQISRETHGSPPHRLSPGKWALRNCLLGMEFSGR DASGKRVMGLVPAEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRMQ PGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDT SFEQHVLRHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFL KNVTFHGVLLDSLMDEGGNSWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRYMAQG KHIGKVVIQVRREEPEAVLRETGPTLMAAVSRTYCPAHKSYVITGGLGGFGLELAQWLVL RGARKLVLTSRSGIRTGYQAKQVREWRRQGIQVLVSTSNASSLDGAQSLIDEATQLGPVG GVFNLAVVLRDAMLENQTPELFQDVNRPKYSGTVNLDRVTRTACPELDYFVAFSSVSCGR GNAGQTNYGFANSTMERVCEKRQHDGLPGLAIQWGAIGDVGIILESMGSNDTVIGGTLPQ RIASCLEVLDLFLNQPHPVLSSFVLAEKKATAHDDGSGQQDPMEAVAHILGIRDLATVNP DSSLADLGLDSLMGVEVRQMLEREHDLVMSMRDIRQLTLRKLQELSSKAGTANELAAPTP KEDTPAGQQAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSITVFHSLASKLS IPTYGLQCTRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAAQ QGPTPAHNSLFLFDGSHAYVLAYTQSYRAKLTPGCEAEAEAEAMCFFLQQFTDMEHNRVL ETLLPLEGLEERVAATVDLITRSHAGLDPRELSFAARSFYHKLRAAEQYTPRATYHGNVT LLRAKTGSVYGEGLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLETILSIIHSSLAEP RVSVREG NT seq 7944 nt NT seq  +upstreamnt  +downstreamnt atggggggggggtggtcaccccaggccagggccccagaagtgccaggccagtgccaaagg ccagagggtccagtcgtcccagtgaaaagtaggggctggctggaccagtgtggactcccc catgcacctgaggcgtctgtcctggccagcccagggcgcaggagctggcctcctggatct tggtctcaccgctcacaaacccgtaggtggtgctgtggggttagaaagccgggggagagg ctgcagcctggtggtctggcagccggatatgaccagcgccaggcccccacattactcccc ctgcacagagcagccatggaggacgttgtgattgctggcatgtccgggaagctgcccgag tcggagaacatggaggagttctgggccaacctcatcggcggcgtggacatggtgacagac gatgacaggaggtggaaggcaggactctacggcctgcccaagcgtaccggcaagctaaag gacctgtccaagttcgatgcctccttcttcggggtccacccaaagcaggctcacacgatg gacccccagctgcgcttgctactggaggtcacctacgaggccatcctggatggaggcatc aacccggctaccctgcgagggacacacacaggcgtctgggtgggcgtgagtggctcggag gcctcagaggctctgagccgagaccccgagactctcctgggctacagcatggtgggctgc cagcgggctatgatggccaaccgcctctcctttttctttgattttaaagggcccagcatc gctctggacacagcctgctcctccagcctgctggcccttcagaacgcctaccaggccatc cgcaggggagagtgccccgcagccatcgtgggcggcctcaacatcctgctcaagcccaac acctccgtgcagttcatgaagctcggcatgctgagccccgacggaacctgcaaggccttc gacgagtccggggacggctactgccgtgcggaggccgtggtggccgtcctgctgaccaag aagtccctggcccggcgtgtgtatgccaccatcctcaacgccggcaccaacacggacggc tgcaaggagcaaggtgtgaccttcccctccggggaggcgcaagaacagctcatccgctcg ctgtacgagccggctgggttgagcccagagtccctcgagtatatcgaagcccacggcaca gggaccaaggtgggggacccccaggagctgaacggtatcgcccaagtcctgtgtccctcc cgccaggagcccctgctgatcgggtccaccaagtcgaacatggggcacccggagcccgct tcagggctcgcggctctggccaaggtgctgctgtccctggagcatgggctctgggccccc aacctgcacttccggagcccgaacaccaagatccctgcgctccaggacggacggctgcag gtggtgcagcagcccctgcccgtccgcggaggcaacgtgtgtatcaattcgttcggcttc ggcggctccaacgtgcacgtcattctccagcccaatccgcggctgccctcggcccccacc cggcacgcctctctgccccgtctgctgcgggccagcggacgcaccccggaggccgtgcac tgcctgctggagcaaggccaccggcacagccaggacctggccttcgtgagcatgctcaat gacatcgcggccatcccccccaccgccatgcccttccggggctacaccgtgctgggtggc aagggcggcagccaggaggtacagcaggtggccgctggcaagcgtccgctctggttcatc tgctcggggatgggcacacagtggtgcgggatgggattgagcctcatgcgcctgggcagc ttccgggactccatcctgcgctccgacgaggccgtgaagcccttgggactgcaggtgtct gagctgctgctgagcacagacgaggccacctttgatgacatcgtccacgccttcgtgagc ctcaccgccatccagatcgccctcatagacctgctgaactccatgggtctgcggcccgac ggaatcatcgggcactccctgggtgaggtggcctgcggctacgcagatggctgcctttct caggaggaggccatcctcgccgcctactggaggggccagtgcatcaaggagaccaacatc ccaccggggaccatggcggccatcggcttgtcctgggaggagtgtaagcagcgctgcccc cctggtgtcgtgcccgcctgccacaactctgaggacacagtgaccatctcgggaccgcag gccgaggtggctgcattcgtggcggagctgaagcaggagggtgtgtttgccaaggaggtg cggacgggcggcatggccttccactcctacttcatggactccatcgcccccacattgctt caggccctcaagaaggtgatccgggagccgcggccccgctcggcacgctggctcagtacc tccatccccgaggcccagtggcagggcagcctggcccgcacgttctcggcggagtataac gtcaacaatctggtgagccccgtgctgttccaggaggcgctgtggcacgtgcccggggac gccgtggtgttggagatcgccccccacgccctgctgcaggccgtcctcaagagaggcctg aagtccagctgtaccatcatccctctgatgaagaaggaccaaagagacaacctggagttc ttcctcagcaacgtgggcaagttgcatctgctgggcttcgacgtcaaccccaatggcctg cttccacccatggagttcccggtgccccggggcactcctctcatctcccctcacatcaag tgggaccacagtcagacctgggacgtccccaccgccaaggacttccccagcggctccagt ggctcctctgcctccaccgtctgcaacatcagcgtcagccctgaatcccctgaccactac ctggtggaccactgcatcgacggccgcgtcctcttccccgccaccggctacctgtgcctg gtctggaagactctggcacggaccttgagtcaaaacatggaacaagtacccgtggtgttt gaggacgtgacactgcaccaggctactgtcctacccaagaccgggaccgtgcccctggaa gtgcggctcctacaggcttcccgtaccttcgaggtgtctgagaacggcaacctgatagtg agcgggaaggtttaccagtgggaggaccccgacgccaagctgttcgacagccgggacggc ccggacaccacggaccccacagctacgttccgcctgagccagagggacgtgtacaaagag ttgaggctgcgtggctatgactacggccctcattttcaaggcatcctcgaggccaacctc gaaggcaacgcgggccggctgctgtggaagaacaactgggtgacgttcctggacgccatg ctgcagacatccatcctgggcctggcccagtgtggcctgcgtctgcccacccgcatcacc tctgtccgcatcgaccccgccacccaccagcgcagggtgtactcgctgctgggcggggcc caagcggtcaacgtggtggtgaacagttgtctgaacagcacggtggccggcggcgtcctc atctcgggcctccacgcctcgatggccccacggcggcagcaggagcagtttgcgcccatc ctggagaagttctgtttcacgccgcacacggaggaggggctcctggctggagacacggcc ctgcaggaggggctgcagctgtgcagggggctggcacgggcgctgcagaccaaggtggcc cagcaggggctgaagatggtggtgtctgggctggacggggcccaggccccccaggagcct ccaaagcaaggcctgccccggctgctggcggccgcctgccagctgcagctcaacgggggc ctccagctggagctgggccagctgctggcccaacagaggcccctgctgcaggacgacccc ctgctcagcggcctcctcgcttccccggcgctcaaagcctgcgtggacaccgccctggag aacatgcccagcctcaagatgaaggtcgtggaggtgctggctggcgatggccacctgtat tctcacatcccggcactgcttaacacccagcccacgctgcagctggagtacacggccact gaccgccaccctcaggccctggaggccgtgcaggccaagctgcagcagcacggcatagcc cagggccagtgggaccctgcagaccccgcccctggcagcctgggctcagctgatctcctc ctgtgtaactgtgcggtggccagcctcggtgacccggccacggccgttggcaacatgggg gccgctctcaaggagggcggcttcctgctgctgcacgctctgctcaaaggacaccccctt ggagagacagtcgccttcctcacctgccccgagccgcggcgaggccagcagagcctccta agccaggacgagtgggagagtctgtttgccggggcgtccctgcacctggtggccctgaag aggtccttctacggctctgtgctcttcctgtgccgtcggccggtcctacaggacagccct gtcttcctgcctgtggaggaccccggtttccagtgggtgaactccctgaagaacattttg gccgactcctcccagcagcccgtgtggctaacagccaccagctgccccgactcaggcgtc gtgggcttggtgaactgtctccgcagagagcctggcgggcaccggattcggtgcatcctg gtgtccaacctcagcagcacgtcccgcacccccagtttggaccccggctcctcggagctg cagaaggtgctacggggggacctcgtgatgaatgtctaccgagacggggcctggggggcc ttccgccatttccccctggagcgcggcctgccagaggagcagaccgagcacgccttcgtg aacgtcctcacgcggggggacctctcctccatccgctgggtctgctcccctctgcgtcac acccagctcaccggccccggcgtccagctctgtgccgtccactatgcttccctcaacttc agagatatcatgctggccacgggcaagctgtcccctgacgccatcccaggtacgggccgg gtaccacggcacagccaggcccaaatctccagggagacgcacggctcacccccccaccgt ctgtccccagggaagtgggccctccgcaactgtttgctgggcatggagttctctggccga gacgccagcggcaagcgtgtcatggggctggtgcccgctgaaggcctggctacctccgtc ctgctctctcaggacttcctgtgggaggtgccctccagctggaccctagaggaggcggct tcggtgcctgtggtctacaccaccgcctactactcgctggtggtgcgggggcgcatgcag cccggggagacggtgctcatccactcaggctcgggcggcgtgggccaggccgccatcgcc atcgccctcagcctgggctgccgcgtcttcactaccgtggggtcagccgagaagcgggcc tacctccaggccaggttcccccagctcgacgacaccagcttcgccaactcccgggacacg tcctttgaacagcacgtgctgcggcacacagcagggaagggtgtggacctggtcctgaat tctctggcagaagaaaagctacaggccagcgtgcggtgcctggcccagcacggccggttc ctggaaatcggcaaattcgacctttcgaacaaccacctgctgggcatggccgtcttcctg aagaacgtgaccttccacggggtcctgctggattcgctcatggatgaaggcgggaacagc tggcaggaggtggctgcgctgctgaaggcaggcatccgggacggcgtggtgcagcccctc aagtgcaccgtgttccccaaggaccgggtggaggacgccttccgctacatggcccaaggg aaacacatcggcaaagtggtcatccaggtgcgcagggaggagccggaggcggtgctgcgg gagacgggtcccaccctgatggccgccgtgtccaggacctactgcccggcccacaagagc tatgtcatcaccgggggcctgggcggcttcggcctggagctggcccagtggcttgtgctg cgaggggcccggaaactcgtgctgacctctcgctctgggatccgcacaggctaccaggcc aagcaggtccgtgagtggaggcgccagggcatacaggtcctggtgtccaccagcaacgcc agctcgctggatggggcccagagcctcatcgatgaggccacgcagctggggcccgtggga ggcgtctttaacctggccgtggtcctgagagacgccatgctggagaaccaaacccctgag ctctttcaggacgtcaacaggcccaagtacagcggcaccgtgaacctggacagggtgacc cgaactgcgtgccccgagctggactactttgtggccttctcctctgtgagctgcgggcgc ggcaacgccggccagaccaactatggcttcgccaactccaccatggagcgcgtgtgtgag aagcgccagcacgacggcctcccgggcctcgccattcagtggggcgccatcggtgacgtg ggcatcatcctggagtccatgggctccaacgatacggtcatcggcgggacgctgccgcag cggattgcctcctgcttggaggtgctggacctcttcctgaaccagccccaccccgtcctg agcagctttgtgctggccgagaagaaggccactgcccacgatgacggcagtggccagcag gacccgatggaggccgtggcccacatcctgggcatccgagacttggccaccgtcaacccg gacagctcgctggcagacctgggtctggactcgctcatgggcgtggaggtgcgccagatg ttggagcgcgagcacgacctggtgatgtccatgcgggacatccggcagctcacgctccgg aagttgcaggagctttcctcgaaggctggcacagccaatgagctggcagcccccacaccc aaggaggacacccctgccggccagcaggcccagctgaacctcagcaccctgctggtgaac cccgagggcccgaccttgacacggctcaactcggtgcagagctctgagcgccccctgttc ctggtgcaccccatcgagggctccatcactgtgttccacagcctggcgtccaagctcagc atccccacctacggcctacagtgcactcgagccgcgcccctggacagcatccagagcctg gccgcctactacatcgagtgcatcaggcaggtgcagccggaggggccctaccgcatcgcc ggctattcctacggggcctgcgtggccttcgagatgtgctcgcagctgcaggccgcgcag cagggccccacccccgcgcacaacagcctcttcttgttcgacggttcgcacgcctatgtg ctggcctacacgcagagctaccgcgcgaagctcacccctggctgtgaggccgaggccgag gccgaggccatgtgcttcttcctgcagcagttcaccgacatggaacacaacagggtgctg gagacgctgctgcccctcgagggcctggaggagcgcgtggcggccaccgtggacttgatc acgcgcagccacgcgggcctggacccccgcgagctgagcttcgcggcgcgctccttctac cacaagctgcgcgcggccgagcagtacaccccccgggccacctaccacggcaacgtgacg ctgctgcgcgccaagacgggcagcgtgtacggcgagggcctgggcgccgactacaacctg tcccaggtgtgcgacggcaaggtgtccgtgcacgtgatcgagggggaccaccgcacgctg ctggagggcagcggcctggagactatcctcagcatcatccacagctccctggccgagccg cgcgtcagcgtccgggagggctaa

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