Panthera leo (lion): 122206187
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Entry
122206187 CDS
T10741
Symbol
FASN
Name
(RefSeq) fatty acid synthase isoform X1
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
plez Panthera leo (lion)
Pathway
plez00061
Fatty acid biosynthesis
plez01100
Metabolic pathways
plez01212
Fatty acid metabolism
plez04152
AMPK signaling pathway
plez04910
Insulin signaling pathway
plez04936
Alcoholic liver disease
Module
plez_M00082
Fatty acid biosynthesis, initiation
plez_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
122206187 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
122206187 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122206187 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122206187 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
plez01004
]
122206187 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plez04147
]
122206187 (FASN)
Enzymes [BR:
plez01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
122206187 (FASN)
Lipid biosynthesis proteins [BR:
plez01004
]
Fatty acid synthase
Animal type
122206187 (FASN)
Exosome [BR:
plez04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
122206187 (FASN)
Exosomal proteins of breast milk
122206187 (FASN)
Exosomal proteins of colorectal cancer cells
122206187 (FASN)
Exosomal proteins of bladder cancer cells
122206187 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
PP-binding
Methyltransf_12
adh_short
PS-DH
Methyltransf_23
Methyltransf_11
Methyltransf_31
Thiolase_N
Methyltransf_25
ACP_SdgA_C
Motif
Other DBs
NCBI-GeneID:
122206187
NCBI-ProteinID:
XP_042771035
LinkDB
All DBs
Position
E1:complement(60392636..60411066)
Genome browser
AA seq
2647 aa
AA seq
DB search
MGGGWSPQARAPEVPGQCQRPEGPVVPVKSRGWLDQCGLPHAPEASVLASPGRRSWPPGS
WSHRSQTRRWCCGVRKPGERLQPGGLAAGYDQRQAPTLLPLHRAAMEDVVIAGMSGKLPE
SENMEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKFDASFFGVHPKQAHTM
DPQLRLLLEVTYEAILDGGINPATLRGTHTGVWVGVSGSEASEALSRDPETLLGYSMVGC
QRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRRGECPAAIVGGLNILLKPN
TSVQFMKLGMLSPDGTCKAFDESGDGYCRAEAVVAVLLTKKSLARRVYATILNAGTNTDG
CKEQGVTFPSGEAQEQLIRSLYEPAGLSPESLEYIEAHGTGTKVGDPQELNGIAQVLCPS
RQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFRSPNTKIPALQDGRLQ
VVQQPLPVRGGNVCINSFGFGGSNVHVILQPNPRLPSAPTRHASLPRLLRASGRTPEAVH
CLLEQGHRHSQDLAFVSMLNDIAAIPPTAMPFRGYTVLGGKGGSQEVQQVAAGKRPLWFI
CSGMGTQWCGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSELLLSTDEATFDDIVHAFVS
LTAIQIALIDLLNSMGLRPDGIIGHSLGEVACGYADGCLSQEEAILAAYWRGQCIKETNI
PPGTMAAIGLSWEECKQRCPPGVVPACHNSEDTVTISGPQAEVAAFVAELKQEGVFAKEV
RTGGMAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEAQWQGSLARTFSAEYN
VNNLVSPVLFQEALWHVPGDAVVLEIAPHALLQAVLKRGLKSSCTIIPLMKKDQRDNLEF
FLSNVGKLHLLGFDVNPNGLLPPMEFPVPRGTPLISPHIKWDHSQTWDVPTAKDFPSGSS
GSSASTVCNISVSPESPDHYLVDHCIDGRVLFPATGYLCLVWKTLARTLSQNMEQVPVVF
EDVTLHQATVLPKTGTVPLEVRLLQASRTFEVSENGNLIVSGKVYQWEDPDAKLFDSRDG
PDTTDPTATFRLSQRDVYKELRLRGYDYGPHFQGILEANLEGNAGRLLWKNNWVTFLDAM
LQTSILGLAQCGLRLPTRITSVRIDPATHQRRVYSLLGGAQAVNVVVNSCLNSTVAGGVL
ISGLHASMAPRRQQEQFAPILEKFCFTPHTEEGLLAGDTALQEGLQLCRGLARALQTKVA
QQGLKMVVSGLDGAQAPQEPPKQGLPRLLAAACQLQLNGGLQLELGQLLAQQRPLLQDDP
LLSGLLASPALKACVDTALENMPSLKMKVVEVLAGDGHLYSHIPALLNTQPTLQLEYTAT
DRHPQALEAVQAKLQQHGIAQGQWDPADPAPGSLGSADLLLCNCAVASLGDPATAVGNMG
AALKEGGFLLLHALLKGHPLGETVAFLTCPEPRRGQQSLLSQDEWESLFAGASLHLVALK
RSFYGSVLFLCRRPVLQDSPVFLPVEDPGFQWVNSLKNILADSSQQPVWLTATSCPDSGV
VGLVNCLRREPGGHRIRCILVSNLSSTSRTPSLDPGSSELQKVLRGDLVMNVYRDGAWGA
FRHFPLERGLPEEQTEHAFVNVLTRGDLSSIRWVCSPLRHTQLTGPGVQLCAVHYASLNF
RDIMLATGKLSPDAIPGTGRVPRHSQAQISRETHGSPPHRLSPGKWALRNCLLGMEFSGR
DASGKRVMGLVPAEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRMQ
PGETVLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDDTSFANSRDT
SFEQHVLRHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFL
KNVTFHGVLLDSLMDEGGNSWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRYMAQG
KHIGKVVIQVRREEPEAVLRETGPTLMAAVSRTYCPAHKSYVITGGLGGFGLELAQWLVL
RGARKLVLTSRSGIRTGYQAKQVREWRRQGIQVLVSTSNASSLDGAQSLIDEATQLGPVG
GVFNLAVVLRDAMLENQTPELFQDVNRPKYSGTVNLDRVTRTACPELDYFVAFSSVSCGR
GNAGQTNYGFANSTMERVCEKRQHDGLPGLAIQWGAIGDVGIILESMGSNDTVIGGTLPQ
RIASCLEVLDLFLNQPHPVLSSFVLAEKKATAHDDGSGQQDPMEAVAHILGIRDLATVNP
DSSLADLGLDSLMGVEVRQMLEREHDLVMSMRDIRQLTLRKLQELSSKAGTANELAAPTP
KEDTPAGQQAQLNLSTLLVNPEGPTLTRLNSVQSSERPLFLVHPIEGSITVFHSLASKLS
IPTYGLQCTRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAAQ
QGPTPAHNSLFLFDGSHAYVLAYTQSYRAKLTPGCEAEAEAEAMCFFLQQFTDMEHNRVL
ETLLPLEGLEERVAATVDLITRSHAGLDPRELSFAARSFYHKLRAAEQYTPRATYHGNVT
LLRAKTGSVYGEGLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLETILSIIHSSLAEP
RVSVREG
NT seq
7944 nt
NT seq
+upstream
nt +downstream
nt
atggggggggggtggtcaccccaggccagggccccagaagtgccaggccagtgccaaagg
ccagagggtccagtcgtcccagtgaaaagtaggggctggctggaccagtgtggactcccc
catgcacctgaggcgtctgtcctggccagcccagggcgcaggagctggcctcctggatct
tggtctcaccgctcacaaacccgtaggtggtgctgtggggttagaaagccgggggagagg
ctgcagcctggtggtctggcagccggatatgaccagcgccaggcccccacattactcccc
ctgcacagagcagccatggaggacgttgtgattgctggcatgtccgggaagctgcccgag
tcggagaacatggaggagttctgggccaacctcatcggcggcgtggacatggtgacagac
gatgacaggaggtggaaggcaggactctacggcctgcccaagcgtaccggcaagctaaag
gacctgtccaagttcgatgcctccttcttcggggtccacccaaagcaggctcacacgatg
gacccccagctgcgcttgctactggaggtcacctacgaggccatcctggatggaggcatc
aacccggctaccctgcgagggacacacacaggcgtctgggtgggcgtgagtggctcggag
gcctcagaggctctgagccgagaccccgagactctcctgggctacagcatggtgggctgc
cagcgggctatgatggccaaccgcctctcctttttctttgattttaaagggcccagcatc
gctctggacacagcctgctcctccagcctgctggcccttcagaacgcctaccaggccatc
cgcaggggagagtgccccgcagccatcgtgggcggcctcaacatcctgctcaagcccaac
acctccgtgcagttcatgaagctcggcatgctgagccccgacggaacctgcaaggccttc
gacgagtccggggacggctactgccgtgcggaggccgtggtggccgtcctgctgaccaag
aagtccctggcccggcgtgtgtatgccaccatcctcaacgccggcaccaacacggacggc
tgcaaggagcaaggtgtgaccttcccctccggggaggcgcaagaacagctcatccgctcg
ctgtacgagccggctgggttgagcccagagtccctcgagtatatcgaagcccacggcaca
gggaccaaggtgggggacccccaggagctgaacggtatcgcccaagtcctgtgtccctcc
cgccaggagcccctgctgatcgggtccaccaagtcgaacatggggcacccggagcccgct
tcagggctcgcggctctggccaaggtgctgctgtccctggagcatgggctctgggccccc
aacctgcacttccggagcccgaacaccaagatccctgcgctccaggacggacggctgcag
gtggtgcagcagcccctgcccgtccgcggaggcaacgtgtgtatcaattcgttcggcttc
ggcggctccaacgtgcacgtcattctccagcccaatccgcggctgccctcggcccccacc
cggcacgcctctctgccccgtctgctgcgggccagcggacgcaccccggaggccgtgcac
tgcctgctggagcaaggccaccggcacagccaggacctggccttcgtgagcatgctcaat
gacatcgcggccatcccccccaccgccatgcccttccggggctacaccgtgctgggtggc
aagggcggcagccaggaggtacagcaggtggccgctggcaagcgtccgctctggttcatc
tgctcggggatgggcacacagtggtgcgggatgggattgagcctcatgcgcctgggcagc
ttccgggactccatcctgcgctccgacgaggccgtgaagcccttgggactgcaggtgtct
gagctgctgctgagcacagacgaggccacctttgatgacatcgtccacgccttcgtgagc
ctcaccgccatccagatcgccctcatagacctgctgaactccatgggtctgcggcccgac
ggaatcatcgggcactccctgggtgaggtggcctgcggctacgcagatggctgcctttct
caggaggaggccatcctcgccgcctactggaggggccagtgcatcaaggagaccaacatc
ccaccggggaccatggcggccatcggcttgtcctgggaggagtgtaagcagcgctgcccc
cctggtgtcgtgcccgcctgccacaactctgaggacacagtgaccatctcgggaccgcag
gccgaggtggctgcattcgtggcggagctgaagcaggagggtgtgtttgccaaggaggtg
cggacgggcggcatggccttccactcctacttcatggactccatcgcccccacattgctt
caggccctcaagaaggtgatccgggagccgcggccccgctcggcacgctggctcagtacc
tccatccccgaggcccagtggcagggcagcctggcccgcacgttctcggcggagtataac
gtcaacaatctggtgagccccgtgctgttccaggaggcgctgtggcacgtgcccggggac
gccgtggtgttggagatcgccccccacgccctgctgcaggccgtcctcaagagaggcctg
aagtccagctgtaccatcatccctctgatgaagaaggaccaaagagacaacctggagttc
ttcctcagcaacgtgggcaagttgcatctgctgggcttcgacgtcaaccccaatggcctg
cttccacccatggagttcccggtgccccggggcactcctctcatctcccctcacatcaag
tgggaccacagtcagacctgggacgtccccaccgccaaggacttccccagcggctccagt
ggctcctctgcctccaccgtctgcaacatcagcgtcagccctgaatcccctgaccactac
ctggtggaccactgcatcgacggccgcgtcctcttccccgccaccggctacctgtgcctg
gtctggaagactctggcacggaccttgagtcaaaacatggaacaagtacccgtggtgttt
gaggacgtgacactgcaccaggctactgtcctacccaagaccgggaccgtgcccctggaa
gtgcggctcctacaggcttcccgtaccttcgaggtgtctgagaacggcaacctgatagtg
agcgggaaggtttaccagtgggaggaccccgacgccaagctgttcgacagccgggacggc
ccggacaccacggaccccacagctacgttccgcctgagccagagggacgtgtacaaagag
ttgaggctgcgtggctatgactacggccctcattttcaaggcatcctcgaggccaacctc
gaaggcaacgcgggccggctgctgtggaagaacaactgggtgacgttcctggacgccatg
ctgcagacatccatcctgggcctggcccagtgtggcctgcgtctgcccacccgcatcacc
tctgtccgcatcgaccccgccacccaccagcgcagggtgtactcgctgctgggcggggcc
caagcggtcaacgtggtggtgaacagttgtctgaacagcacggtggccggcggcgtcctc
atctcgggcctccacgcctcgatggccccacggcggcagcaggagcagtttgcgcccatc
ctggagaagttctgtttcacgccgcacacggaggaggggctcctggctggagacacggcc
ctgcaggaggggctgcagctgtgcagggggctggcacgggcgctgcagaccaaggtggcc
cagcaggggctgaagatggtggtgtctgggctggacggggcccaggccccccaggagcct
ccaaagcaaggcctgccccggctgctggcggccgcctgccagctgcagctcaacgggggc
ctccagctggagctgggccagctgctggcccaacagaggcccctgctgcaggacgacccc
ctgctcagcggcctcctcgcttccccggcgctcaaagcctgcgtggacaccgccctggag
aacatgcccagcctcaagatgaaggtcgtggaggtgctggctggcgatggccacctgtat
tctcacatcccggcactgcttaacacccagcccacgctgcagctggagtacacggccact
gaccgccaccctcaggccctggaggccgtgcaggccaagctgcagcagcacggcatagcc
cagggccagtgggaccctgcagaccccgcccctggcagcctgggctcagctgatctcctc
ctgtgtaactgtgcggtggccagcctcggtgacccggccacggccgttggcaacatgggg
gccgctctcaaggagggcggcttcctgctgctgcacgctctgctcaaaggacaccccctt
ggagagacagtcgccttcctcacctgccccgagccgcggcgaggccagcagagcctccta
agccaggacgagtgggagagtctgtttgccggggcgtccctgcacctggtggccctgaag
aggtccttctacggctctgtgctcttcctgtgccgtcggccggtcctacaggacagccct
gtcttcctgcctgtggaggaccccggtttccagtgggtgaactccctgaagaacattttg
gccgactcctcccagcagcccgtgtggctaacagccaccagctgccccgactcaggcgtc
gtgggcttggtgaactgtctccgcagagagcctggcgggcaccggattcggtgcatcctg
gtgtccaacctcagcagcacgtcccgcacccccagtttggaccccggctcctcggagctg
cagaaggtgctacggggggacctcgtgatgaatgtctaccgagacggggcctggggggcc
ttccgccatttccccctggagcgcggcctgccagaggagcagaccgagcacgccttcgtg
aacgtcctcacgcggggggacctctcctccatccgctgggtctgctcccctctgcgtcac
acccagctcaccggccccggcgtccagctctgtgccgtccactatgcttccctcaacttc
agagatatcatgctggccacgggcaagctgtcccctgacgccatcccaggtacgggccgg
gtaccacggcacagccaggcccaaatctccagggagacgcacggctcacccccccaccgt
ctgtccccagggaagtgggccctccgcaactgtttgctgggcatggagttctctggccga
gacgccagcggcaagcgtgtcatggggctggtgcccgctgaaggcctggctacctccgtc
ctgctctctcaggacttcctgtgggaggtgccctccagctggaccctagaggaggcggct
tcggtgcctgtggtctacaccaccgcctactactcgctggtggtgcgggggcgcatgcag
cccggggagacggtgctcatccactcaggctcgggcggcgtgggccaggccgccatcgcc
atcgccctcagcctgggctgccgcgtcttcactaccgtggggtcagccgagaagcgggcc
tacctccaggccaggttcccccagctcgacgacaccagcttcgccaactcccgggacacg
tcctttgaacagcacgtgctgcggcacacagcagggaagggtgtggacctggtcctgaat
tctctggcagaagaaaagctacaggccagcgtgcggtgcctggcccagcacggccggttc
ctggaaatcggcaaattcgacctttcgaacaaccacctgctgggcatggccgtcttcctg
aagaacgtgaccttccacggggtcctgctggattcgctcatggatgaaggcgggaacagc
tggcaggaggtggctgcgctgctgaaggcaggcatccgggacggcgtggtgcagcccctc
aagtgcaccgtgttccccaaggaccgggtggaggacgccttccgctacatggcccaaggg
aaacacatcggcaaagtggtcatccaggtgcgcagggaggagccggaggcggtgctgcgg
gagacgggtcccaccctgatggccgccgtgtccaggacctactgcccggcccacaagagc
tatgtcatcaccgggggcctgggcggcttcggcctggagctggcccagtggcttgtgctg
cgaggggcccggaaactcgtgctgacctctcgctctgggatccgcacaggctaccaggcc
aagcaggtccgtgagtggaggcgccagggcatacaggtcctggtgtccaccagcaacgcc
agctcgctggatggggcccagagcctcatcgatgaggccacgcagctggggcccgtggga
ggcgtctttaacctggccgtggtcctgagagacgccatgctggagaaccaaacccctgag
ctctttcaggacgtcaacaggcccaagtacagcggcaccgtgaacctggacagggtgacc
cgaactgcgtgccccgagctggactactttgtggccttctcctctgtgagctgcgggcgc
ggcaacgccggccagaccaactatggcttcgccaactccaccatggagcgcgtgtgtgag
aagcgccagcacgacggcctcccgggcctcgccattcagtggggcgccatcggtgacgtg
ggcatcatcctggagtccatgggctccaacgatacggtcatcggcgggacgctgccgcag
cggattgcctcctgcttggaggtgctggacctcttcctgaaccagccccaccccgtcctg
agcagctttgtgctggccgagaagaaggccactgcccacgatgacggcagtggccagcag
gacccgatggaggccgtggcccacatcctgggcatccgagacttggccaccgtcaacccg
gacagctcgctggcagacctgggtctggactcgctcatgggcgtggaggtgcgccagatg
ttggagcgcgagcacgacctggtgatgtccatgcgggacatccggcagctcacgctccgg
aagttgcaggagctttcctcgaaggctggcacagccaatgagctggcagcccccacaccc
aaggaggacacccctgccggccagcaggcccagctgaacctcagcaccctgctggtgaac
cccgagggcccgaccttgacacggctcaactcggtgcagagctctgagcgccccctgttc
ctggtgcaccccatcgagggctccatcactgtgttccacagcctggcgtccaagctcagc
atccccacctacggcctacagtgcactcgagccgcgcccctggacagcatccagagcctg
gccgcctactacatcgagtgcatcaggcaggtgcagccggaggggccctaccgcatcgcc
ggctattcctacggggcctgcgtggccttcgagatgtgctcgcagctgcaggccgcgcag
cagggccccacccccgcgcacaacagcctcttcttgttcgacggttcgcacgcctatgtg
ctggcctacacgcagagctaccgcgcgaagctcacccctggctgtgaggccgaggccgag
gccgaggccatgtgcttcttcctgcagcagttcaccgacatggaacacaacagggtgctg
gagacgctgctgcccctcgagggcctggaggagcgcgtggcggccaccgtggacttgatc
acgcgcagccacgcgggcctggacccccgcgagctgagcttcgcggcgcgctccttctac
cacaagctgcgcgcggccgagcagtacaccccccgggccacctaccacggcaacgtgacg
ctgctgcgcgccaagacgggcagcgtgtacggcgagggcctgggcgccgactacaacctg
tcccaggtgtgcgacggcaaggtgtccgtgcacgtgatcgagggggaccaccgcacgctg
ctggagggcagcggcctggagactatcctcagcatcatccacagctccctggccgagccg
cgcgtcagcgtccgggagggctaa
DBGET
integrated database retrieval system
