Panthera leo (lion): 122207917 Help Entry 122207917         CDS       T10741                                  Symbol SPHK2 Name (RefSeq) sphingosine kinase 2 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism plez  Panthera leo (lion) Pathway plez00600   Sphingolipid metabolism plez01100   Metabolic pathways plez04020   Calcium signaling pathway plez04071   Sphingolipid signaling pathway plez04072   Phospholipase D signaling pathway plez04148   Efferocytosis plez04370   VEGF signaling pathway plez04371   Apelin signaling pathway plez04666   Fc gamma R-mediated phagocytosis plez05152   Tuberculosis Module plez_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     122207917 (SPHK2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     122207917 (SPHK2)    04371 Apelin signaling pathway     122207917 (SPHK2)    04020 Calcium signaling pathway     122207917 (SPHK2)    04072 Phospholipase D signaling pathway     122207917 (SPHK2)    04071 Sphingolipid signaling pathway     122207917 (SPHK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     122207917 (SPHK2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     122207917 (SPHK2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     122207917 (SPHK2) Enzymes [BR:plez01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      122207917 (SPHK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  122207917 NCBI-ProteinID:  XP_042774209 LinkDB All DBs Position E2:complement(9124067..9132800) Genome browser AA seq 680 aa AA seqDB search MHTLPPPLGLMGAVGADLRGRPEEDSACEEGAGRPDQELTWSWGHRPRSALDGAKAMAPP PPPPLAASTPLLHGEFGSFPARSSRFALTLTPQALHIQRLRPKPEARPRGGLVPLAEVSG CCTLRSRSPSDAAAAYFCIYTYPQGRRGGRRRAARTFRVDGAATYEENRAEAQRWATALM CLLRGLPLPGDGEITPELLPKPPRLLLLVNPLGGRGLAWQWCKTHVLPMISEAGLSFNLI QTERQNHARELVQGLRLSEWDGIVTVSGDGLLFEVLNGFLDRPDWEEAVKTPVGILPCGS GNALAGAVNQHGGFEPALGVDLLLNCSLLLCRGGSRPLDLMSVTLASGSRCLSFLSVAWG FVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPTSPTPARGLPRAK SELTLAPAPAPAPPVAHSPLHRSVSDLPLPLPLPQPALTSPGSPEPLPILSLNGGGPELA GDWGGAGDAPLSPDPPLPSPPSSPKAALLSPITEGVPETLASSGLPPPTPGSPGAVSTRG PHDHLLPPLGTPLPPGWVTLEGDFVLMLAISPSHLGADLVAAPHARFDDGLVHLCWVRGG ISRAALLRLFLAMERGSHFSLGCPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQ MHPGLGTLLTGPPGCPRREP NT seq 2043 nt NT seq  +upstreamnt  +downstreamnt atgcacaccctccccccacccctgggtctgatgggggcggttggtgctgacttgaggggc cgcccggaggaggactcggcgtgtgaggagggtgcggggaggccagaccaggagctgacc tggagctggggccacaggcctagaagcgccctggacggggccaaggccatggccccccca ccgccgccaccattggccgccagcaccccgctcctgcatggcgagtttggctccttcccg gcccgcagctcccgcttcgccctcactctcacaccacaggccctacacatacagcggctg cgcccaaagcctgaagcccggccccggggcggcctggtcccgctggccgaggtgtccggc tgctgcaccctgcggagccgcagcccctcggacgcagcagcggcctacttctgcatctac acctatccgcagggccggcgcgggggccggcgcagagccgcccgcacctttcgggtcgac ggggcggccacctacgaggagaaccgcgctgaggcccagcgctgggccactgccctcatg tgtctgctccgtggactgccgctgcctggggacggggaaataacccccgagcttctgcca aagccaccccgattgctcctattggtcaatccccttggggggcggggcctggcctggcag tggtgtaagacccacgtgctgcccatgatctccgaagctgggctgtccttcaacctcatc cagacagaacgacagaaccatgcccgggagctggttcaggggctgaggctgagtgagtgg gacggcattgtcacggtctccggagacgggctgctgtttgaggtgctgaacggattcctg gaccgccctgactgggaagaggctgtgaagacgcccgtgggcatcctcccctgtggctca ggcaatgccttggccggagctgtgaaccagcatggggggtttgaacctgccctgggtgtg gacctgctgctcaattgctcgctgctactctgccggggcggcagccgcccgctggacctg atgtctgtgacgctggcctccggctcccgctgcttgtccttcctgtctgtggcctggggc ttcgtgtcagacgtggatatccagagcgagcgcttcagggccctgggcagtgcccgcttc acactgggcacagtgctgggcctcgccacactgcacacctaccgaggacgcctctcctac ctccctgccactgtggagcccacctcacccacccctgcccgtggcctgccccgtgccaag tcagagctgaccctggccccggccccggccccagccccacctgtggcacactcacccctg catcgttcagtgtctgacctgcccctgcccctgcccctgccccagcccgccctgacctcc cctggctcgcctgaacccctgcccatcctgtccctcaatggcgggggcccagagttggcc ggggactggggtggggctggggatgcccccctgtccccagacccaccactgccctcaccg cctagctcccctaaggcagctttactgtcacccatcaccgagggggtcccagaaacgttg gcatcctctgggcttccccctcccacccccggctctccaggagccgtctctaccaggggc ccgcatgaccacctgctccctcctctgggcaccccactccccccaggctgggtgacgctg gagggggactttgtgctcatgctggccatctcacctagccacctgggggcagacctggtg gcagctccccacgcgcgctttgacgacggcctggtgcacctgtgctgggtgcgtggtggc atctcccgggctgcgctgctacgcctctttctggccatggagcgaggtagccacttcagc ctgggctgtccgcagctgggctacgccgcggcccgtgccttccgcctcgagccgctcacg cctcggggcgtgctcactgtggacggagagcaggtggagtacgggccactgcaggcgcag atgcacccgggcctcggcacgctgctcactgggcctcccggctgcccacgtcgggagcct tga

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