Panthera leo (lion): 122208577
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Entry
122208577 CDS
T10741
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase
KO
K01398
matrix metalloproteinase-2 (gelatinase A) [EC:
3.4.24.24
]
Organism
plez
Panthera leo (lion)
Pathway
plez01522
Endocrine resistance
plez04670
Leukocyte transendothelial migration
plez04912
GnRH signaling pathway
plez04915
Estrogen signaling pathway
plez04926
Relaxin signaling pathway
plez04933
AGE-RAGE signaling pathway in diabetic complications
plez05200
Pathways in cancer
plez05205
Proteoglycans in cancer
plez05219
Bladder cancer
plez05415
Diabetic cardiomyopathy
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
122208577 (MMP2)
09152 Endocrine system
04912 GnRH signaling pathway
122208577 (MMP2)
04915 Estrogen signaling pathway
122208577 (MMP2)
04926 Relaxin signaling pathway
122208577 (MMP2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122208577 (MMP2)
05205 Proteoglycans in cancer
122208577 (MMP2)
09162 Cancer: specific types
05219 Bladder cancer
122208577 (MMP2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122208577 (MMP2)
05415 Diabetic cardiomyopathy
122208577 (MMP2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122208577 (MMP2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
122208577 (MMP2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122208577 (MMP2)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.24 gelatinase A
122208577 (MMP2)
Peptidases and inhibitors [BR:
plez01002
]
Metallo peptidases
Family M10
122208577 (MMP2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Peptidase_M10
fn2
Hemopexin
PG_binding_1
Reprolysin_3
Reprolysin_5
Peptidase_M66
Motif
Other DBs
NCBI-GeneID:
122208577
NCBI-ProteinID:
XP_042775713
LinkDB
All DBs
Position
E2:32664348..32687374
Genome browser
AA seq
661 aa
AA seq
DB search
MTEARGARGALAGPLRALCVLGCLLGRAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYG
CPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQSTIETMRKPRCGNPDVANYNFFPRKPKW
DKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLF
NGKEYTSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQG
TSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNK
HESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGA
LMAPIYTYTKNFRLSHDDIKGIQELYGASPDIDTGTGPTPTLGPVTPEICKQDIVFDGIS
QIRGEIFFFKDRFIWRTVTPRSKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNE
YWVYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNRKTYIFAGDKFWRYNEVKKKMD
PGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLG
C
NT seq
1986 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaggcgcgaggggcccggggcgcactcgccggcccgctgcgggcgctctgcgtc
ctgggctgcctgttgggccgcgccgccgccgcgccgtcgcccatcatcaagttccctgga
gatgtggcccccaaaacggacaaagagctggccgtgcaatatctgaacaccttctacggc
tgccccaaggagagctgtaacctgttcgtgctcaaggacacactaaagaagatgcagaag
ttctttgggctgccccagacgggtgaccttgaccagagcacgattgagaccatgcggaag
cctcgctgtggcaaccctgatgtggccaactacaacttcttcccccgcaagcccaagtgg
gacaagaaccagatcacatacaggatcattggctacacgcctgatctggaccccgagaca
gtggatgatgcctttgctcgtgccttccaagtctggagtgatgtaaccccgctaaggttt
tctcgtatccacgatggagaggcggacatcatgatcaactttggccgctgggagcacgga
gatggatacccctttgatggcaaggacgggctcctggctcacgcctttgccccgggccct
ggcgtcgggggagactcccactttgacgacgatgagctgtggaccctgggagaagggcaa
gtggtccgcgtgaagtacgggaacgccgacggggagtactgcaagttccccttcctgttc
aacggcaaggaatacacgagctgcacggacacgggccgcagcgacggcttcctctggtgc
tccaccacctacaactttgaaaaggatggcaaatacggcttctgcccccacgaagccctg
ttcaccatgggtggcaatgctgacggacagccctgcaagttcccattccgcttccaggga
acatcctacgacagctgcaccactgagggccgcaccgacggctaccgctggtgcgggacc
acggaagactacgaccgagacaagaagtatggcttctgccccgagaccgccatgtccact
gttggcgggaactcagaaggtgccccctgtgtcttccccttcaccttcttgggcaacaag
catgagagctgtacgagcgcgggccgcagcgatgggaagatgtggtgtgcgaccacagcc
aactatgacgatgaccgcaagtggggcttctgccctgaccaagggtacagcttgttcctg
gttgcagcccatgagtttggccatgcaatggggctggagcactctcaggaccctggggcc
ctgatggcacccatttatacctacaccaagaacttccgcctgtcccacgacgacatcaag
ggcattcaagagctctatggggcctcccctgacattgacactggcaccggccccacccca
actctcggccccgtcactcctgagatctgcaaacaggacattgtttttgatggcatctct
cagatccggggcgagatcttcttcttcaaggacaggttcatttggcgaacagtgacacca
cgtagcaagcccatggggcccctgctggtggccacattctggcctgagctcccggaaaag
attgatgctgtatacgaggccccacaggaggagaaggctgtgttctttgcagggaatgaa
tactgggtctattcagccagcaccctggagcgagggtaccccaagccgctgaccagcctg
gggctgccccctgacgtccagcgggtagatgctgcgtttaactggagcaagaacaggaag
acctacatctttgctggagacaagttctggaggtacaatgaagtaaagaagaagatggac
cctggcttccccaagctcatcgcggatgcctggaacgccatccccgataacctggacgcc
gtggtcgacctgcagggcggtggtcacagctacttcttcaagggcgcgtattacctgaag
ttggagaaccagagtctgaagagcgtgaaatttggaagcatcaaatccgactggctgggc
tgctga
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