Panthera leo (lion): 122209443 Help Entry 122209443         CDS       T10741                                  Symbol ACTB Name (RefSeq) actin, cytoplasmic 1   KO K05692   actin beta/gamma 1 Organism plez  Panthera leo (lion) Pathway plez03082   ATP-dependent chromatin remodeling plez04015   Rap1 signaling pathway plez04145   Phagosome plez04210   Apoptosis plez04390   Hippo signaling pathway plez04510   Focal adhesion plez04517   IgSF CAM signaling plez04518   Integrin signaling plez04520   Adherens junction plez04530   Tight junction plez04611   Platelet activation plez04613   Neutrophil extracellular trap formation plez04670   Leukocyte transendothelial migration plez04714   Thermogenesis plez04810   Regulation of actin cytoskeleton plez04814   Motor proteins plez04820   Cytoskeleton in muscle cells plez04919   Thyroid hormone signaling pathway plez04921   Oxytocin signaling pathway plez04971   Gastric acid secretion plez05014   Amyotrophic lateral sclerosis plez05100   Bacterial invasion of epithelial cells plez05132   Salmonella infection plez05135   Yersinia infection plez05164   Influenza A plez05205   Proteoglycans in cancer plez05225   Hepatocellular carcinoma plez05410   Hypertrophic cardiomyopathy plez05412   Arrhythmogenic right ventricular cardiomyopathy plez05414   Dilated cardiomyopathy plez05416   Viral myocarditis plez05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:plez00001]  09120 Genetic Information Processing   09126 Chromosome    03082 ATP-dependent chromatin remodeling     122209443 (ACTB)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122209443 (ACTB)    04390 Hippo signaling pathway     122209443 (ACTB)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     122209443 (ACTB)    04518 Integrin signaling     122209443 (ACTB)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     122209443 (ACTB)   09143 Cell growth and death    04210 Apoptosis     122209443 (ACTB)   09144 Cellular community - eukaryotes    04510 Focal adhesion     122209443 (ACTB)    04520 Adherens junction     122209443 (ACTB)    04530 Tight junction     122209443 (ACTB)   09142 Cell motility    04814 Motor proteins     122209443 (ACTB)    04820 Cytoskeleton in muscle cells     122209443 (ACTB)    04810 Regulation of actin cytoskeleton     122209443 (ACTB)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122209443 (ACTB)    04613 Neutrophil extracellular trap formation     122209443 (ACTB)    04670 Leukocyte transendothelial migration     122209443 (ACTB)   09152 Endocrine system    04921 Oxytocin signaling pathway     122209443 (ACTB)    04919 Thyroid hormone signaling pathway     122209443 (ACTB)   09154 Digestive system    04971 Gastric acid secretion     122209443 (ACTB)   09159 Environmental adaptation    04714 Thermogenesis     122209443 (ACTB)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     122209443 (ACTB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     122209443 (ACTB)   09172 Infectious disease: viral    05164 Influenza A     122209443 (ACTB)   09171 Infectious disease: bacterial    05132 Salmonella infection     122209443 (ACTB)    05135 Yersinia infection     122209443 (ACTB)    05100 Bacterial invasion of epithelial cells     122209443 (ACTB)   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     122209443 (ACTB)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     122209443 (ACTB)    05410 Hypertrophic cardiomyopathy     122209443 (ACTB)    05412 Arrhythmogenic right ventricular cardiomyopathy     122209443 (ACTB)    05414 Dilated cardiomyopathy     122209443 (ACTB)    05416 Viral myocarditis     122209443 (ACTB)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:plez03021]     122209443 (ACTB)    03019 Messenger RNA biogenesis [BR:plez03019]     122209443 (ACTB)    03036 Chromosome and associated proteins [BR:plez03036]     122209443 (ACTB)    03029 Mitochondrial biogenesis [BR:plez03029]     122209443 (ACTB)   09183 Protein families: signaling and cellular processes    04812 Cytoskeleton proteins [BR:plez04812]     122209443 (ACTB)    04147 Exosome [BR:plez04147]     122209443 (ACTB) Transcription machinery [BR:plez03021]  Eukaryotic type   RNA polymerase II system    Coactivators     BAF/PBAF complex      122209443 (ACTB) Messenger RNA biogenesis [BR:plez03019]  Eukaryotic type   mRNA surveillance and transport factors    Factors involved in mRNA localization     Factors that have mRNA localization signals      122209443 (ACTB) Chromosome and associated proteins [BR:plez03036]  Eukaryotic type   Histone modification proteins    HAT complexes     TIP60 complex      122209443 (ACTB)     NuA4 complex      122209443 (ACTB)   Chromatin remodeling factors    BAF complex     122209443 (ACTB)    PBAF complex     122209443 (ACTB)    GBAF(ncBAF) complex     122209443 (ACTB)    SWR1 complex     122209443 (ACTB) Mitochondrial biogenesis [BR:plez03029]  Mitochondrial quality control factors   Mitochondrial dynamics    Actin cytoskeleton organization     122209443 (ACTB) Cytoskeleton proteins [BR:plez04812]  Eukaryotic cytoskeleton proteins   Actin filaments / Microfilaments    Actins     Actins      122209443 (ACTB) Exosome [BR:plez04147]  Exosomal proteins   Proteins found in most exosomes    122209443 (ACTB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Actin DUF6581 Motif Other DBs NCBI-GeneID:  122209443 NCBI-ProteinID:  XP_042777215 UniProt:  A0A8C9D802 LinkDB All DBs Position E3:complement(4120003..4123500) Genome browser AA seq 375 aa AA seqDB search MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ EYDESGPSIVHRKCF NT seq 1128 nt NT seq  +upstreamnt  +downstreamnt atggatgatgatattgctgcgctcgtggtcgacaacggctccggcatgtgcaaggccggc ttcgcgggcgacgatgccccacgggccgtcttcccttccatcgtggggcgcccccggcac cagggcgtgatggtgggtatgggccagaaggactcctacgtgggcgatgaggcccagagc aagaggggcatcctgaccctgaagtaccccatcgagcacggtattgtcaccaactgggac gacatggagaagatctggcatcacactttctacaacgagctgcgtgtggcccccgaggag cacccagtgctgctgaccgaggcccccctgaaccccaaggccaaccgtgagaagatgacc cagatcatgttcgagaccttcaacaccccggccatgtacgtggccatccaggccgtgctg tccctgtacgcctctggccgcaccaccggcatcgtgatggactccggggacggggtcacc cacactgtgcccatctacgaggggtacgccctgccccacgccatcctgcgtctggacctg gctggccgggacctgacggactacctcatgaagatcctcacggagcgcggctacagcttc accaccaccgccgagcgggaaattgtgcgtgacatcaaggagaagctctgctacgtggcc ttggacttcgagcaggagatggccaccgccgcgtcctcttcctccctggagaagagctac gagctgcccgacgggcaggtgatcaccatcggcaacgagcggttccgctgccccgaggcg ctcttccagccttccttcctgggcatggaatcctgtggcatccacgaaactaccttcaac tccatcatgaagtgcgacgtcgacatccgcaaggacctctacgccaacacggtgctgtct ggggggaccaccatgtaccccggcatcgctgaccggatgcagaaggagatcaccgccctg gcgcccagcacgatgaagatcaagatcatcgcaccccctgagcgcaagtactccgtgtgg atcggtggctccatcctggcctcgctgtccaccttccagcagatgtggatcagcaagcag gagtatgacgagtccggcccctccatcgtccaccgcaaatgcttctag

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