KEGG   Panthera leo (lion): 122210061
Entry
122210061         CDS       T10741                                 
Symbol
PDGFA
Name
(RefSeq) LOW QUALITY PROTEIN: platelet-derived growth factor subunit A
  KO
K04359  platelet-derived growth factor subunit A
Organism
plez  Panthera leo (lion)
Pathway
plez01521  EGFR tyrosine kinase inhibitor resistance
plez04010  MAPK signaling pathway
plez04014  Ras signaling pathway
plez04015  Rap1 signaling pathway
plez04020  Calcium signaling pathway
plez04072  Phospholipase D signaling pathway
plez04151  PI3K-Akt signaling pathway
plez04510  Focal adhesion
plez04540  Gap junction
plez04630  JAK-STAT signaling pathway
plez04810  Regulation of actin cytoskeleton
plez05200  Pathways in cancer
plez05202  Transcriptional misregulation in cancer
plez05206  MicroRNAs in cancer
plez05214  Glioma
plez05215  Prostate cancer
plez05218  Melanoma
plez05231  Choline metabolism in cancer
plez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122210061 (PDGFA)
   04014 Ras signaling pathway
    122210061 (PDGFA)
   04015 Rap1 signaling pathway
    122210061 (PDGFA)
   04630 JAK-STAT signaling pathway
    122210061 (PDGFA)
   04020 Calcium signaling pathway
    122210061 (PDGFA)
   04072 Phospholipase D signaling pathway
    122210061 (PDGFA)
   04151 PI3K-Akt signaling pathway
    122210061 (PDGFA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122210061 (PDGFA)
   04540 Gap junction
    122210061 (PDGFA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122210061 (PDGFA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122210061 (PDGFA)
   05202 Transcriptional misregulation in cancer
    122210061 (PDGFA)
   05206 MicroRNAs in cancer
    122210061 (PDGFA)
   05231 Choline metabolism in cancer
    122210061 (PDGFA)
  09162 Cancer: specific types
   05214 Glioma
    122210061 (PDGFA)
   05218 Melanoma
    122210061 (PDGFA)
   05215 Prostate cancer
    122210061 (PDGFA)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    122210061 (PDGFA)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122210061 (PDGFA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:plez04052]
    122210061 (PDGFA)
   00536 Glycosaminoglycan binding proteins [BR:plez00536]
    122210061 (PDGFA)
Cytokines and neuropeptides [BR:plez04052]
 Cytokines
  Growth factors (RTK binding)
   122210061 (PDGFA)
Glycosaminoglycan binding proteins [BR:plez00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   122210061 (PDGFA)
SSDB
Motif
Pfam: PDGF_N PDGF
Other DBs
NCBI-GeneID: 122210061
NCBI-ProteinID: XP_042778418
LinkDB
Position
E3:complement(348815..367264)
AA seq 211 aa
MRTWACLLLFGCGYLAHALAEEAEIPHEVIERLAHSHIHSIRDLQRLLEIDSVGPEGPLE
ASLRAHGGHSSKHAPEKRPVPIRRKRSIEEAIPAVCKTRTVIYEIPRSQVDPTSANFLIW
PPCVEVKRCAGCCNTSSVKCQPSRVHHRSVKVAKVEYIRKKPKLKEVQVRLEEHLECTCT
ATGPTPDHREEETGRRRESGKKRKRKRLKPT
NT seq 636 nt   +upstreamnt  +downstreamnt
atgaggacctgggcttgcctgctgctcttcggctgcggatacctcgcccatgccctggcc
gaggaagccgagatcccccacgaggtgattgagaggctggcgcacagtcacatccacagc
atccgggacctccagcgactcctggagatagactccgtagggcccgagggtcctctggag
gcgagtctgagagcccacgggggccactcctccaagcatgcgcccgagaagcggcccgtg
cccattcggaggaagagaagcattgaggaagccatccccgcggtctgcaagaccagaacg
gtcatttacgagatacctcggagtcaggtcgaccccacgtctgccaacttcctgatctgg
cccccgtgcgtggaggtgaagcgctgtgcgggctgctgcaacaccagcagcgtcaagtgc
cagccttcccgcgtccaccaccggagcgtcaaggtggccaaggtggagtacatcaggaag
aagccaaagttaaaggaggtgcaggtccggctggaggagcatttggagtgcacgtgcacg
gccaccggcccgaccccggaccaccgggaggaggagacaggaaggcgtagggagtcaggt
aaaaaacggaaaagaaaaaggttaaaacccacctaa

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