Panthera leo (lion): 122211150
Help
Entry
122211150 CDS
T10741
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
plez Panthera leo (lion)
Pathway
plez01522
Endocrine resistance
plez04012
ErbB signaling pathway
plez04062
Chemokine signaling pathway
plez04148
Efferocytosis
plez04151
PI3K-Akt signaling pathway
plez04360
Axon guidance
plez04370
VEGF signaling pathway
plez04510
Focal adhesion
plez04670
Leukocyte transendothelial migration
plez04810
Regulation of actin cytoskeleton
plez04935
Growth hormone synthesis, secretion and action
plez05100
Bacterial invasion of epithelial cells
plez05135
Yersinia infection
plez05146
Amoebiasis
plez05163
Human cytomegalovirus infection
plez05165
Human papillomavirus infection
plez05170
Human immunodeficiency virus 1 infection
plez05200
Pathways in cancer
plez05202
Transcriptional misregulation in cancer
plez05205
Proteoglycans in cancer
plez05208
Chemical carcinogenesis - reactive oxygen species
plez05222
Small cell lung cancer
plez05417
Lipid and atherosclerosis
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122211150 (PTK2)
04370 VEGF signaling pathway
122211150 (PTK2)
04151 PI3K-Akt signaling pathway
122211150 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122211150 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122211150 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122211150 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
122211150 (PTK2)
04062 Chemokine signaling pathway
122211150 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
122211150 (PTK2)
09158 Development and regeneration
04360 Axon guidance
122211150 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122211150 (PTK2)
05202 Transcriptional misregulation in cancer
122211150 (PTK2)
05205 Proteoglycans in cancer
122211150 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
122211150 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
122211150 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122211150 (PTK2)
05163 Human cytomegalovirus infection
122211150 (PTK2)
05165 Human papillomavirus infection
122211150 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122211150 (PTK2)
05100 Bacterial invasion of epithelial cells
122211150 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
122211150 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122211150 (PTK2)
05418 Fluid shear stress and atherosclerosis
122211150 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
122211150 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122211150 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
plez01009
]
122211150 (PTK2)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122211150 (PTK2)
Protein kinases [BR:
plez01001
]
Non-receptor tyrosine kinases
FAK family
122211150 (PTK2)
Protein phosphatases and associated proteins [BR:
plez01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122211150 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
122211150
NCBI-ProteinID:
XP_042780197
LinkDB
All DBs
Position
F2:complement(80028204..80285839)
Genome browser
AA seq
1109 aa
AA seq
DB search
MLVELAGREALRPAGAVCMEKSGCGPFPMCWAKDYDRYIAPSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIG
EGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLVGV
ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAA
RNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFG
VCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRF
TELKAQLSTILEEEKVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGF
YPSPQHMVQTNHYQVSGYPGSHGVTATAGSIYPGQASLLDQTDSWNHRPQEISMWQPNVE
DSAALDLRGIGQVLPTQLVEERLIRQQQEMEEDQRWLEKEERFLVILKPDVRLSRGSIDR
EDGSLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWR
LQPQEISPPPTANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRT
LLATVDETLPVLPASTHREIEMAQKLLNSDLGELINKMKLAQRCAMTSLQQDHKKQMLTA
AHALAVDAKNLLDVIDQARLRALGHARPR
NT seq
3330 nt
NT seq
+upstream
nt +downstream
nt
atgttggtggaactggcgggccgagaggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtggtccatttccaatgtgttgggctaaagattatgacagatacatagca
ccaagcaaaataatggcagctgcttaccttgacccaaacttgaatcacaccccgaattcg
agtaccaagacccatctgggtaccggagtggaacgttcccccggggcaatggagcgagtg
ttgaaggtctttcattattttgagaacagcagtgagccagccacttgggccagtattatc
aggcacggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaaaagtgactacatg
tcggagatagctgaccgggtggaccaggacatcgctttgaagctgggctgcctagaaata
cggcgctcgtattgggagatgcgaggcaacgcgctagagaagaagtccaactatgaggtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaaactgatccagcagacatttagacagttcgccaacctgaacaga
gaagagagcattctgaaattctttgagatcctctccccagtgtaccgatttgataaagag
tgcttcaagtgtgccctcggttcaagctggattatttcagtggaactggcgatcggccca
gaagaaggaatcagttacctcacggacaagggctgcagccccacacatctggccgacttc
aatcaagtgcagaccattcagtattccaacagcgaagacaaggacaggaaaggaacgctg
cagctgaaaatcgcgggcgcccccgagcctctgacagtgacagcaccgtccctgaccatc
gccgagaatatggctgacctgatagatgggtactgccggctggtgaacggagccacgcag
tcctttatcatcaggccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctccgtgtcagaaaccgacgac
tatgctgagattatagacgaagaagatacctacaccatgccctcaaaaagctatggaata
gacgaagccagggactacgagattcaaagagaaaggatcgagcttggacggtgcatcggg
gaaggccagtttggggacgtccaccaaggcgtctacatgagtccagagaatccggctttg
gcggtcgcaattaaaacatgtaaaaactgtacttcggacagcgtgcgagagaaattcctt
caagaagccttaacgatgcgccagtttgaccacccccacatcgtgaagctggtcggtgtc
atcacggagaaccccgtctggataatcatggagttgtgcacgcttggagagctgaggtcg
tttctgcaagtgaggaagtacagtttggatctcgcgtctttgatcctgtatgcctatcag
cttagtacagctctggcgtatctggagagcaaaagattcgtgcacagggacattgctgct
cggaatgttctggtgtcctcaaatgattgcgtaaaattaggagactttggattatcccgg
tatatggaagacagtacttactacaaagcttccaaaggaaagttgcctattaaatggatg
gctccagagtccatcaactttcgacgttttacctcagccagtgacgtgtggatgtttggt
gtgtgtatgtgggagatactgatgcatggtgtgaagccgtttcaaggagtgaagaacaat
gatgtgatcggtcgaatcgagaacggggagagattaccaatgcctccaaattgccctccc
accctctacagccttatgacgaaatgctgggcctatgaccccagcaggcggccccggttc
actgagctcaaagctcagctcagcaccatcctggaggaggagaaggttcagcaagaagaa
cgaatgaggatggaatcccgaagacaggtcacagtgtcctgggactccggagggtccgac
gaagcgccacccaagcccagcagacctggctaccccagtccgcggtccagcgaaggattt
tatcccagtccccagcacatggtacagaccaatcattaccaggtgtctggctatcctggt
tcacatggggtcacagccacggctggcagcatctacccgggtcaggcatctcttttggac
cagacggactcatggaatcacagaccacaggagatatcgatgtggcagcccaacgtggag
gactctgcggccctggacctgcgcgggatcgggcaggtgctgcccacccagctggtggaa
gagcggctgatccggcagcagcaggaaatggaggaggaccagcgctggctcgagaaagag
gagagattcctggtcatcctgaaacccgacgtgcggctctctcgaggcagcatcgacagg
gaggacgggagtcttcagggcccgacgggaaaccaacacatctatcagcctgtgggtaaa
ccagatcccgcagctccgccaaagaaaccgccgcggcctggagcccccggtcacctgggc
agcctcgccagcctcagcagccccggggacagttacaacgagggcgtcaagccatggagg
cttcagccccaggaaatcagccccccgcccactgccaacctggaccggtccaacgacagg
gtgtacgagaatgtgacgggcctggtgaaggctgtcatcgaaatgtccagcaagatccag
ccagcccccccggaggagtacgttcccatggtgaaggaagtcggcctggccctgcggaca
ttactggccaccgtggacgagacccttccagtcctgccagccagcactcaccgagagatc
gagatggcccagaagctgttgaactccgacctgggcgagctcatcaacaagatgaagctg
gcccagcggtgcgccatgaccagcctacagcaggaccacaagaagcagatgctgaccgct
gcccacgccctggccgtggacgccaagaacttactcgacgtcatcgaccaggccagactg
agggcactcggacacgcgaggccgcgctga
DBGET
integrated database retrieval system
