Panthera leo (lion): 122215969 Help Entry 122215969         CDS       T10741                                  Name (RefSeq) tyrosine-protein kinase ZAP-70   KO K07360   tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] Organism plez  Panthera leo (lion) Pathway plez04014   Ras signaling pathway plez04064   NF-kappa B signaling pathway plez04650   Natural killer cell mediated cytotoxicity plez04658   Th1 and Th2 cell differentiation plez04659   Th17 cell differentiation plez04660   T cell receptor signaling pathway plez05135   Yersinia infection plez05235   PD-L1 expression and PD-1 checkpoint pathway in cancer plez05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:plez00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     122215969    04064 NF-kappa B signaling pathway     122215969  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     122215969    04660 T cell receptor signaling pathway     122215969    04658 Th1 and Th2 cell differentiation     122215969    04659 Th17 cell differentiation     122215969  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     122215969   09171 Infectious disease: bacterial    05135 Yersinia infection     122215969   09163 Immune disease    05340 Primary immunodeficiency     122215969  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:plez01001]     122215969 Enzymes [BR:plez01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      122215969 Protein kinases [BR:plez01001]  Non-receptor tyrosine kinases   SYK family    122215969 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 DUF7063 DUF7145 ABC1 SH2_1 Haspin_kinase RIO1 Kdo Motif Other DBs NCBI-GeneID:  122215969 NCBI-ProteinID:  XP_042787996 LinkDB All DBs Position A3:complement(62040240..62062742) Genome browser AA seq 619 aa AA seqDB search MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFP IERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRD AMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG SQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK LKADGLIYCLKDACPNSSASASSEAAAPTLPAHPSTFTHAQRRIDTLNSDGYTPEPARLV STEKPRPMPMDTSVYESPYSDPEELKDKKLFLKRENLLIADIELGCGNFGSVRQGVYRMR KKQIDVAIKVLKHSTEKTDKDEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGG PLHKFLLGKKEEIPISNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDF GLSKALGADDSYYTARSAGKWPLKWYAPECFNFRKFSSRSDVWSYGVTMWEAFSYGQKPY KKMKGPEVIAFIEQGKRMECPPDCPPEMYTLMSDCWIYKWEDRPDFLAVEQRMRTYYYSL ASKTEDPPGPGKGTETAFA NT seq 1860 nt NT seq  +upstreamnt  +downstreamnt atgccggaccccgcggcgcacctgcccttcttctatggcagcatctcgcgcgccgaggcg gaggagcacctgaagctggcgggcatggccgacgggctctttctgctgcgccagtgcctg cgctcgctgggcggctacgtgctctcgctcgtgcacgatgtgcgtttccaccacttcccc atcgagcgccagctcaacggcacttacgccatcgctggcggtaaggcgcactgcggccct gccgagctctgcgagttctactcgcgcgatcccgacggtctgccctgcaacctgcgcaag ccgtgcaaccggccatccgggctcgagcctcagcccggggtcttcgattgcctgcgcgac gccatggtgcgcgactacgtgcgccagacgtggaagctggagggtgaggccctggagcag gccatcatcagccaggctccccaggtggagaagctcattgccacaacagctcacgagagg atgccctggtaccacagcagcctgactcgagaggaggcagagcgcaaactctattcgggc tcgcagaccgacggcaagttcctgctgaggccccggaaggagcagggcacgtacgcactg tccctgatctacgggaaaaccgtataccactacctcatcagccaggacaaggcaggcaaa tactgtattcctgaggggaccaagtttgacacgctctggcagctggtagagtacctgaag ctgaaggctgatgggctcatctactgcctgaaggatgcctgccccaactccagcgccagc gccagctcagaggctgctgctcccacactcccagctcacccatccactttcacccatgct cagagacggattgatacccttaactcagatggatacacccctgaaccagcacgcctagtg tccacagagaagccaaggccaatgcccatggacacaagtgtgtacgagagcccctacagt gaccctgaggagctcaaggacaagaagctcttcctgaagcgtgagaacctcctcatcgct gacatagaacttggctgtggcaactttggctcagtgcgccagggcgtctatcgcatgcgc aagaagcagattgacgtcgccatcaaggtgttgaagcacagcacggagaagacagacaag gatgagatgatgcgcgaggcgcagattatgcaccagctggacaacccctacatcgtgcgg ctcatcggcgtctgccaggccgaggccctcatgctcgtcatggagatggcgggcggcggg cccctgcacaagttcctgcttgggaagaaggaggagatccccatcagcaacgtggcggag ctgctgcaccaggtgtccatggggatgaagtacctggaggagaaaaattttgtgcaccgt gacctggcagcccgcaacgtcctgctggtcaaccggcactacgccaagatcagcgacttc ggtctctccaaggcactgggtgccgacgacagctactatactgcccgctcggcagggaag tggccgctcaagtggtatgcgcccgagtgtttcaacttccgcaagttctccagccgcagt gatgtttggagctatggggtcaccatgtgggaggccttctcctatggccagaagccctac aagaagatgaagggccctgaagtcatagccttcatcgagcagggcaagaggatggagtgc ccgccagactgtccacctgaaatgtacacactcatgagtgactgctggatctacaagtgg gaagaccgcccagacttcctggctgtggagcagcgcatgcggacctactattacagcttg gcgagcaagactgaggaccccccggggcctggaaagggaaccgagactgcttttgcctga

DBGET integrated database retrieval system