Panthera leo (lion): 122216452
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Entry
122216452 CDS
T10741
Name
(RefSeq) xanthine dehydrogenase/oxidase isoform X1
KO
K00106
xanthine dehydrogenase/oxidase [EC:
1.17.1.4
1.17.3.2
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez00232
Caffeine metabolism
plez00983
Drug metabolism - other enzymes
plez01100
Metabolic pathways
plez01232
Nucleotide metabolism
plez04146
Peroxisome
Module
plez_M00958
Adenine ribonucleotide degradation, AMP => Urate
plez_M00959
Guanine ribonucleotide degradation, GMP => Urate
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122216452
09110 Biosynthesis of other secondary metabolites
00232 Caffeine metabolism
122216452
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
122216452
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
122216452
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plez04147
]
122216452
Enzymes [BR:
plez01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.1 With NAD+ or NADP+ as acceptor
1.17.1.4 xanthine dehydrogenase
122216452
1.17.3 With oxygen as acceptor
1.17.3.2 xanthine oxidase
122216452
Exosome [BR:
plez04147
]
Exosomal proteins
Exosomal proteins of breast milk
122216452
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MoCoBD_2
MoCoBD_1
FAD_binding_5
Ald_Xan_dh_C
Fer2_2
CO_deh_flav_C
Fer2
Motif
Other DBs
NCBI-GeneID:
122216452
NCBI-ProteinID:
XP_042789244
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Position
A3:114399771..114457539
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AA seq
1334 aa
AA seq
DB search
MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI
VMSMYTLLRNQPEPTIEEIEDAFQGNLCRCTGYRPILQGFRTFARDGGCCGGSGNDLNCC
MNQKTDHKQITLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDTPQKQLRFEGERVTWIQA
STLQELLDLKAQDPEAKLVVGNTEIGIEMKFKNKLFPKMVCPAWIPELNSVEHGPEGISF
GASCPLSFVEKTLLDAVANLPAHQTEVFKGVLEQLRWFAGKQVKSVASIGGNIITASPIS
DLNPVFMASGAKLTIVSTGTRRTVRMDHTFFPAYRKTLLAPEEILLSIEIPYSREGEYFS
AFKQASRREDDIAKVTSGMRVLFNPETAQVKELALCYGGMHDRTVSALKTTRKQIANFWN
EELLQNVCAGLAEELSLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGIQNSKDKCGKL
DPTHASATLLFQKDPPANVQLFQEVPKGQCEEDMVGRPLPHLAAAMQASGEAVYCDDIPR
YENELSLRLVTSTRAHAKIKSIDTSEAQKVPGFVCFISADDVPGSNITGIGNDEMVFAKD
KVTCIGHIIGAVVTDTREHAQRAAQAVRITYEDLPAIITIEDAIAKDSFYEPELKIEKGN
LTKGFSEADNIVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTTKTQSFVAN
MLGVPANRILVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGCPVRCMLDRDEDMLITGG
RHPFLARYKVGFMKTGRVVALKVEHYSNAGNTLDLSQSIMERALFHMDNCYNIPNIRGTG
RMCKTNLPSNTAFRGFGGPQGMLIAEHWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQK
LEGFTLPRCWEECLASSQYHARKREVDKFNEENCWKKRGLSIIPTKFGISFSVPFLNQGG
ALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTA
ASVSTDLNGQATYEACQTILKRLEPFKKKNPSGSWEDWVIAAYLDAVSLSATGFYKTPNL
GYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA
FVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPSEFRVSLLRDCPNKKAIYASKA
VGEPPLFLAASIFFAIKDAIRAARAGNPDCKTKKLFQLNSPATPEKIRNACVDQFTRLCV
TGTAESCKPWSVRV
NT seq
4005 nt
NT seq
+upstream
nt +downstream
nt
atgacagcggatgagttggttttctttgtgaacggcaaaaaggtggtggagaagaatgcg
gacccagaaacaacccttttggcctacctgagaagaaaattggggctgagcgggaccaaa
ctgggctgtggagaagggggctgcggggcttgcacggtgatgctttccaagtatgatcgt
ttccagaacaagatcgtccacttttctgccaatgcctgcctggcccccatctgctctttg
catcatgttgccgtgacgactgtggaaggaataggaagcaccaagtcgaggctgcatcct
gtgcaggagagaattgccaaaagccatggctcccagtgcgggttctgcacccctggcatc
gtcatgagcatgtacacgctgctccggaaccagcctgagcccaccattgaggagatcgag
gatgccttccaaggaaacctgtgtcgctgcacgggctacagacccatcctccagggcttc
cggaccttcgccagggatggtgggtgctgcggaggaagtgggaacgacctgaactgttgc
atgaaccagaagacagaccacaagcagatcactctctcgccatctctattcaacccggag
gagttcatgcccctggatcccacccaggaacccatcttccccccagagttgctgaggctg
aaagatactcctcagaaacagctgcgttttgaaggcgagcgagtgacctggatccaggcc
tcaaccctgcaggagctgctggacctcaaagcccaggaccccgaggccaagctggtggtg
gggaacacggagatcggcattgagatgaaatttaagaataagctgtttcctaagatggtc
tgcccagcctggatccctgagctgaattcagtggagcatggacctgagggtatctccttc
ggagcctcgtgtcccttgagctttgtggaaaagacgctgctcgatgcagtcgccaacctt
cctgcccaccaaacagaggtgttcaaaggtgttttggagcagctgcgctggtttgctggg
aagcaggtcaagtctgtggcgtccatcggagggaacatcatcaccgccagccccatctct
gacctcaaccctgtgttcatggccagtggggccaagctgaccatcgtgtccacaggcacc
aggaggacggttcggatggatcacaccttcttccccgcgtacagaaagaccctgctagct
ccggaggagatactgctttccatcgagatcccctacagcagggagggtgagtatttctca
gcctttaagcaggcctctcggagagaagatgacatcgccaaggtgaccagcggcatgagg
gtcctgttcaacccggaaaccgcgcaggtgaaggagctggccctttgctacggcggaatg
cacgacagaaccgtctcggccctcaagaccacacggaagcagatagcaaatttctggaac
gaggagctgctgcagaacgtgtgtgcgggcctggcggaggagttgtccctggcccccgac
gcccctggcggcatggtggagtttcggcgtaccctcaccctcagcttcttcttcaagttc
tacctgacagtgcttcagaaactgggcatacagaactcgaaagataagtgcggcaagctg
gaccccacccatgccagtgccaccttactctttcagaaagaccctccagccaacgtccag
ctcttccaagaggtgcccaagggtcagtgcgaggaggacatggtgggtcggcccctgccc
cacctggccgcggccatgcaagcgtctggggaggccgtgtactgtgacgacatccctcgc
tacgagaatgagctgtccctccggttggtcaccagcacccgggcccacgccaagatcaag
tccatagatacttcagaagctcagaaggtgccagggtttgtctgctttatctctgctgat
gatgttcccgggagtaatataactggaattggtaatgatgaaatggtgtttgcaaaggat
aaggtgacttgcattgggcacatcattggtgctgtggtcaccgacacccgagaacatgcc
cagagagctgctcaagcggtgagaatcacctatgaagatcttccagccattatcacaata
gaggatgctatagcaaaagactccttttatgagcctgagctgaagatagagaaaggaaac
ctcacgaaggggttttcggaagcagacaacattgtttcaggcgagttgtacattggtggc
caagagcacttctacctggagactcactgcaccatcgctgtccccaaaggcgaggcaggg
gagatggagctctttgtgtctacacagaacaccacgaagacccagagctttgttgcaaac
atgttgggggttccggcaaaccggattttggtccgggtgaagagaatgggaggaggcttt
ggagggaaagagacccggagcactgtggtatccacagcagtggctctggctgcatacaag
acgggctgccctgtgcgctgcatgctggatcgtgacgaggacatgctgataactggtggc
agacatcccttcttggccagatacaaggttggcttcatgaagactgggagggttgtggct
ctgaaggtggagcattacagcaatgcagggaacaccctggatctctcccagagtataatg
gaacgagctctattccacatggacaactgttataacatccccaacatccggggcactggg
cggatgtgcaagaccaacctgccctccaacacggctttcaggggctttggggggccccag
ggaatgctcattgctgagcattggatgagcgaagtcgcagtgacctgtgggctgccggca
gaggaagtgcgaaggaaaaacatgtataaggaaggggacctgacccacttcaaccagaag
cttgaggggttcaccttgcccaggtgctgggaggaatgcctagcaagctctcagtatcat
gcccggaagagggaggttgacaagttcaacgaggagaattgttggaagaagagagggttg
tccataattcctaccaagtttggaataagcttctctgttccttttctgaatcagggagga
gccctggttcacgtgtacacagatggctctgtgctgctgacccatggaggcactgagatg
ggccaaggccttcacaccaagatggtccaggtggccagcagagcactgaaaatccccacc
tctaagatttacatcagcgagacaagcacgaacaccgtgcctaacacgtctcccacagct
gcctccgtcagcactgacctcaacggacaggccacctatgaagcttgtcagaccattctg
aaaaggctggaacccttcaagaaaaagaatcccagtggctcctgggaagactgggtcata
gctgcctacctggatgcagtgagcttgtctgctaccgggttttataaaacacccaacctt
ggctacagctttgagacgaactctgggaatcccttccactacttcagctatggggtggct
tgctctgaagtggaaatcgactgcttaacaggggatcataaaaacctccgcacagacatt
gtcatggatgtcggctccagtctgaaccctgccattgatattggacaggtagaaggggcg
tttgtccagggccttggcctgttcaccctggaggagctgcactactccccggaggggagc
ctgcacacccgtggccccagcacctacaagatccctgcgtttggcagcatccccagtgag
ttcagggtgtcgctgctccgtgactgtcccaacaagaaggccatctatgcttccaaggct
gtcggcgaaccgcccctcttcctggcagcctccatcttcttcgccatcaaggatgccatc
cgtgcagctcgagctgggaacccggattgtaagacaaagaagcttttccagctaaacagc
cccgccaccccggagaagatccgcaacgcctgcgtggaccagttcaccaggctgtgtgtc
actggcactgcagaaagctgtaagccctggtctgtgagggtctga
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