Panthera leo (lion): 122217206
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Entry
122217206 CDS
T10741
Symbol
ALDH7A1
Name
(RefSeq) alpha-aminoadipic semialdehyde dehydrogenase isoform X1
KO
K14085
aldehyde dehydrogenase family 7 member A1 [EC:
1.2.1.31
1.2.1.8
1.2.1.3
]
Organism
plez Panthera leo (lion)
Pathway
plez00010
Glycolysis / Gluconeogenesis
plez00053
Ascorbate and aldarate metabolism
plez00071
Fatty acid degradation
plez00260
Glycine, serine and threonine metabolism
plez00280
Valine, leucine and isoleucine degradation
plez00310
Lysine degradation
plez00330
Arginine and proline metabolism
plez00340
Histidine metabolism
plez00380
Tryptophan metabolism
plez00410
beta-Alanine metabolism
plez00561
Glycerolipid metabolism
plez00620
Pyruvate metabolism
plez00670
One carbon pool by folate
plez01100
Metabolic pathways
plez04936
Alcoholic liver disease
Module
plez_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
plez_M00555
Betaine biosynthesis, choline => betaine
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122217206 (ALDH7A1)
00053 Ascorbate and aldarate metabolism
122217206 (ALDH7A1)
00620 Pyruvate metabolism
122217206 (ALDH7A1)
09103 Lipid metabolism
00071 Fatty acid degradation
122217206 (ALDH7A1)
00561 Glycerolipid metabolism
122217206 (ALDH7A1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
122217206 (ALDH7A1)
00280 Valine, leucine and isoleucine degradation
122217206 (ALDH7A1)
00310 Lysine degradation
122217206 (ALDH7A1)
00330 Arginine and proline metabolism
122217206 (ALDH7A1)
00340 Histidine metabolism
122217206 (ALDH7A1)
00380 Tryptophan metabolism
122217206 (ALDH7A1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
122217206 (ALDH7A1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122217206 (ALDH7A1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122217206 (ALDH7A1)
Enzymes [BR:
plez01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
122217206 (ALDH7A1)
1.2.1.8 betaine-aldehyde dehydrogenase
122217206 (ALDH7A1)
1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
122217206 (ALDH7A1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-GeneID:
122217206
NCBI-ProteinID:
XP_042789980
LinkDB
All DBs
Position
A1:complement(104222669..104261685)
Genome browser
AA seq
539 aa
AA seq
DB search
MWRVPRQLCAHLLRGSKLSDAWNRPAAFMSTLLINQAQYAWLKELGLREENEGVYNGSWG
GRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWRIWAEVPAPKRGEVVRQIGDA
LREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERPGHALIE
QWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLED
NKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVALMVQERFGRSLLELGGN
NAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFLHESIHDEVVNRLKKAYAQIRVG
NPWDSNVLYGPLHTKQSVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLAHD
ASIAHTETFAPILYVFKFKSEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGI
VNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgcgtgccccgccagctgtgtgcgcacctcttgaggggaagcaagctctcggac
gcttggaacaggcctgccgccttcatgtccactttgctcatcaatcaggcccagtacgct
tggctgaaggagctggggctccgcgaggaaaacgagggcgtgtataatggaagttgggga
ggccggggagaggttatcacgacttattgtcctgctaacaatgaaccaatagcaagagtc
cgacaggccagcgtggctgactatgaagaaactgtgaagaaagcaagggaagcatggaga
atctgggcagaggttcctgctccgaagagaggagaagtagtgagacagattggggatgcc
ttgcgggagaagatccaagtactaggaagtttggtgtctttggagatggggaaaatctta
gtggaaggtgtaggagaagttcaagagtacgtggatatttgtgattatgctgttggctta
tcacggatgattgggggacccatcttgccttctgaaagacctggacatgccctcattgaa
cagtggaatcctgtaggcctggttggcatcatcactgcgttcaacttccctgtggcagtg
tatggctggaacaatgccattgccatgatctgtgggaatgtctgcctttggaaaggagct
ccaacaacttccctcattagtgtagctgtcacaaagataatagccaaggttctagaagac
aacaaacttcctggtgctatttgttccttgacctgtggtggagcagatataggcactgca
atggccaaagatgaacgggtgaacctgctgtccttcaccgggagcacacaggtgggaaaa
caggtggcccttatggtgcaggagaggtttgggagaagtttgttagaacttggaggaaac
aatgccatcattgcttttgaggatgcagacctcagcttggtcgttccgtcggctctcttc
gcagccgtggggacagcgggccagagatgtaccactgcgcggcgcctgtttttacatgag
agcatccatgatgaagttgtaaatagacttaaaaaggcctatgcacagatccgtgtgggg
aacccttgggactctaatgtcctctacgggccactccacaccaaacagtcagtgagcatg
tttcttggagcagtagaagaagcaaagaaagaaggtggcactgtggtctatggtggcaag
gttatggatcgccctggaaattacgtagaaccaaccattgtgacaggtctggcccacgat
gcgtccattgcccacacagaaacgtttgctccgatcctttatgtctttaaattcaagagt
gaagaagaagtgtttgcatggaataatgaagtaaaacagggactttcaagtagcatcttt
accaaggatttgggcagaatcttccgctggcttgggccgaaaggatcagactgtggcatt
gtaaacgtcaatatcccaacgagtggggcagaaattggaggtgcatttggaggagaaaag
cacactggcggcggccgcgagtctggtagcgatgcctggaaacagtacatgagaagatcc
acttgcaccatcaactacagtaaggaccttcctctagctcaaggaatcaagtttcagtaa
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