Panthera leo (lion): 122217594 Help Entry 122217594         CDS       T10741                                  Symbol IDO1 Name (RefSeq) indoleamine 2,3-dioxygenase 1   KO K00463   indoleamine 2,3-dioxygenase [EC:1.13.11.52] Organism plez  Panthera leo (lion) Pathway plez00380   Tryptophan metabolism plez01100   Metabolic pathways plez01240   Biosynthesis of cofactors plez05143   African trypanosomiasis Module plez_M00038   Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate plez_M00912   NAD biosynthesis, tryptophan => quinolinate => NAD Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09105 Amino acid metabolism    00380 Tryptophan metabolism     122217594 (IDO1)  09160 Human Diseases   09174 Infectious disease: parasitic    05143 African trypanosomiasis     122217594 (IDO1) Enzymes [BR:plez01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.52  indoleamine 2,3-dioxygenase      122217594 (IDO1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IDO PrnB DUF924 VPS18_solenoid_2nd Motif Other DBs NCBI-GeneID:  122217594 NCBI-ProteinID:  XP_042790699 UniProt:  A0A8C8WHZ7 LinkDB All DBs Position B1:complement(42598186..42611833) Genome browser AA seq 407 aa AA seqDB search MSHNRILPTKNSWKNLKEYHIDEEVGFVLPTPQEELPYPYDQWISIAKNLPELIEKNELR KEVEKLKMFSIDDLKDHKSQRLAHLVLGYITMAYVWNQGGEDVCEVLPKNIAVPYCELSK KLDLPPILVYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCGKGFFLVSLLVEIAAAS AIKVIPDLLNAVKCEDHNTLQRALRYIASCLQQAQEEFKQIHEYVDPNTFFNVLRIYLSG WKGNPLLPEGLKYEGVWETPKKFAGGSAAQSSVFQCFDVLLGIQQSSGEESSFKFLQEMR EYMPLAHRKFLQSLESAPSVREFVISKGDAKLKADYNECVKAMANLRKYHLKIVAKYIVI PSRNKHKTNSTSEETSEPENKGTGGTSVMTFLKSVRNTTEKFLLNVD NT seq 1224 nt NT seq  +upstreamnt  +downstreamnt atgtcacacaataggatattgcctacaaaaaattcttggaaaaatttgaaagaataccat atagatgaagaggtgggcttcgttctgccaactccacaggaggaactaccttacccttat gatcaatggatttccattgctaaaaacctgcctgaacttattgagaaaaatgaactacgt aaagaagttgagaagttaaaaatgttcagtattgatgacctcaaagaccacaagtcacag cgccttgcacatctggtcctggggtatatcaccatggcgtatgtgtggaaccaagggggt gaagatgtttgtgaggtcttgccaaagaatattgctgttccttactgtgaactgtctaag aagctggatctgcctcctattctggtttatgcagattgtgtcttggcaaactggaagaaa aaggatcccaatgggcccatgacttatgagaacatggacattctgttttcgtttcctggt ggagactgcggtaaaggatttttcctggtttctctgttggtggaaatagcagcagcttct gcaatcaaagtaattcctgatttattgaatgcagtaaaatgtgaggaccacaatactctg caaagggcactgcgttacatagcttcttgtctgcaacaagcccaggaagagtttaaacaa attcatgaatatgtggatccaaacacatttttcaatgttcttcgcatatacttgtctggc tggaaaggcaaccccctgctgccagagggtctgaagtatgaaggtgtctgggaaacccca aagaagtttgcagggggtagtgcagcccaaagcagcgtcttccagtgctttgatgttctg ctgggcatccagcagagttctggtgaagaatcttctttcaaattccttcaggaaatgaga gaatatatgccattagctcaccggaaatttctccagtcattagagtcagccccctcagtc cgtgagtttgttatttcaaaaggtgatgctaaactgaaggcagattataatgaatgcgtg aaagctatggctaacctgagaaaataccatttgaaaatagtagccaagtacatcgtgatt ccttcaaggaacaagcacaagacaaactccacatctgaagaaacatcagaaccagaaaat aaaggaactggaggcactagtgtcatgactttcctgaagagtgttagaaatacaactgag aaattcctgctgaacgttgactaa

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