Panthera leo (lion): 122217610
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Entry
122217610 CDS
T10741
Symbol
NSD3
Name
(RefSeq) histone-lysine N-methyltransferase NSD3 isoform X1
KO
K11425
[histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:
2.1.1.370
2.1.1.371
]
Organism
plez Panthera leo (lion)
Pathway
plez00310
Lysine degradation
plez01100
Metabolic pathways
Brite
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.370 [histone H3]-lysine4 N-dimethyltransferase
122217610 (NSD3)
2.1.1.371 [histone H3]-lysine27 N-dimethyltransferase
122217610 (NSD3)
Chromosome and associated proteins [BR:
plez03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
122217610 (NSD3)
BRITE hierarchy
SSDB
Ortholog
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122217610
NCBI-ProteinID:
XP_042790748
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Position
B1:44283838..44395493
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AA seq
1447 aa
AA seq
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MDFSFSFMQGIMGNTIQQPPQLIDSANIRQEDAFDNNSDIVEDGGQTPYEATLQQGFQYP
PTTEDLPPLTNGYPPSISMYETQTKYQSYNQYPNGSANGFGAVRNFSPTDYYHSEIPNTR
PHEILEKPSPPQPPPPPSVPQTVIPKKTGSPEIKLKITKTIQNGRELFESSLCGDLLNEV
QASEHTKSKHESRKEKRKKSNKHDSSRSEERKSHKIPKLEPEEQNRPNERIDTVSEKPRD
DPVLKEEPPVQPILSSVPTTEVSAGVKFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKI
NTRGAREYHVQFFSNQPERAWVHEKRVREYKGHKQYEELLAEATKQASNHSEKQKIRKPR
PQRERAQWDIGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQAKKNVASKAEVKKTR
RPRSVPNTQPEQTDAGEVASSPSSTEIRRQSQRRHTSVEEEEPPPVKIAWKTAAARKSLP
ASITMHKGSLDLQKCNMSPVVKIEQVFALQNATGDGKFIDQFVYSTKGIGNKTEISVRGQ
DRLIISTPNQRSEKATQNISSPEATSGPTGSIEKKQQRRSIRTRSESEKSTEVVPKKKIK
KEQVETVPQATVKTGLQKGASEISDSCKPLKKRSRASTDVEMTSSAYRDTSDSDSRGLSD
LQVGFGKQVDSPSATADVDVSDVQSVDSSLSRRGIGISKKDTVCQICESSGDSLIPCEGE
CCKHFHLECLGLASPPDGKFICVECKTGQHPCFSCKVSGTDVKRCSVGACGKFYHEACVR
KFPTAIFESKGFRCPQHCCSACSMEKDIYKASKGRMMRCLRCPVAYHSGDACIAAGSIFV
SSYILICSNHSKRSSSSSSAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLNESNRA
ELMKLPMIPSSSASKKKCEKVIKTVYLFQGGRLLCCESCPASFHPECLSIEMPEGCWNCN
DCKAGKKLHYKQIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYW
VHQGRVFPYVEGDKSFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEIEKNSRKP
PPYKHIKANKVIGKVQIHVADLSEIPRCNCKPADENPCGLESECLNRMLQYECHPQVCPA
GERCQNQCFTKRLYPDAEIIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKR
AHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCD
IPAGMELTFNYNLDCLGNGRTECHCGAENCSGFLGVRPKPTCASTTEEKAKNAKLKQKRR
KIKAEPKQMHEDYCFQCGDGGELVMCDKKDCPKAYHLLCLNLTQPPYGKWECPWHQCGEC
GSAAVSFCEFCPRSFCKDHREGALVPSALEGRLCCSEHDPESPVSAEYWSKIKCKLESQD
RGEDLRE
NT seq
4344 nt
NT seq
+upstream
nt +downstream
nt
atggatttctctttctctttcatgcaagggatcatgggaaacacaattcagcaaccacct
caactcattgactccgccaacatccgtcaggaggatgcctttgataacaacagtgacatt
gttgaagatggtggccagacaccatatgaagctaccttgcagcaaggctttcagtatcca
cctacaacagaagatcttcctccactcacaaatggctatccaccatcgatcagcatgtat
gaaactcaaaccaaataccagtcatataatcagtatcccaatgggtcagccaatggcttt
ggtgcagttagaaactttagccccactgactattaccattcagaaattccaaacacaaga
ccacatgaaattctggaaaaaccttctcctccacagccaccacctcctccttcggtacca
caaactgtgattccaaagaagactggctcacctgaaattaaactaaaaataaccaaaact
atccagaatggcagggaattgtttgagtcttccctttgtggagaccttttaaatgaagta
caggcaagtgagcacacaaaatcaaagcatgaaagcagaaaggaaaagaggaaaaaaagc
aacaagcatgactcatctagatctgaagagcgcaagtcacacaaaatccccaaattagaa
ccagaggaacaaaatagaccaaatgagaggattgacactgtgtcagaaaaaccaagagac
gatccagtactaaaagaggaacccccggttcagccaatattatcttctgttccaacaaca
gaagtgtcagctggtgttaagttccaggttggcgatcttgtttggtctaaggtgggaacc
tatccttggtggccttgcatggtttcaagtgatccccagctcgaggttcataccaaaatt
aacacaagaggtgcccgggaatatcacgtccaattttttagcaaccagccagagagggcc
tgggttcatgaaaagcgagtacgagagtataagggtcataaacagtatgaagaattattg
gctgaagcaaccaaacaagccagcaatcactctgagaaacaaaagattcggaaaccccga
cctcagagagaacgtgctcagtgggatattggcattgcccatgcagagaaagcattgaaa
atgacccgagaggaaagaatagaacagtatacttttatctatattgataaacagcccgag
gaggctttatcccaagcaaaaaagaatgttgcctccaaagccgaagttaagaaaacacga
agaccaaggtcagtgccgaatactcagccagaacagaccgatgcaggtgaggtggcctcc
tcaccatcaagtactgaaattcggagacagagccagaggcggcacacaagtgtggaagag
gaagaaccacctcctgttaaaatagcctggaaaacggctgcagcgaggaaatctttacca
gcttccattacaatgcacaaagggagcctggatttgcagaagtgtaacatgtctccagtt
gtgaaaattgaacaagtgtttgctcttcagaatgccacaggagatgggaaatttatcgat
caatttgtttattcaacgaagggaattggtaacaaaacggaaataagtgtcaggggacaa
gacagacttatcatttccacaccaaaccagagaagtgaaaaggcaactcagaatatatca
tctcctgaagcaacatctggtcctacaggctcaatagaaaagaagcaacagagaagatca
attagaactcgttctgaatcagagaaatccactgaggttgtgccaaagaagaagatcaaa
aaggagcaggttgaaacagttcctcaggctacagtgaagactggattacagaaaggtgcc
agcgagatttcagattcctgtaaacctctaaagaaaaggagtcgcgcctccactgatgta
gaaatgactagttcagcatacagagacacgtctgactccgattctagaggactgagtgac
ctgcaggtaggctttggaaagcaagtagatagcccttctgctactgcagatgtagatgtt
tctgatgtgcagtctgtggattcaagtttgtcaagaagaggcattggaatcagtaagaag
gacactgtgtgtcagatctgtgaaagctctggtgactctctgattccttgtgagggagag
tgctgcaaacactttcacctggagtgcctgggattggcatcaccccctgatggaaagttc
atctgtgtggaatgtaaaaccggacagcacccatgtttttcatgtaaagtgtctggtaca
gatgtgaagcgttgctctgttggtgcttgtgggaaattttatcatgaagcctgtgttcgc
aaattccccactgccatctttgaatcaaaaggattccgctgtccccagcactgttgctct
gcctgttccatggagaaagatatctacaaagcaagtaaaggtcgcatgatgagatgtttg
agatgtccagtagcctatcactctggagatgcttgcattgctgccggaagcatatttgta
tcctcctacattctcatctgtagtaatcattccaaacggagcagcagttcatcctctgcc
ataaatgtaggcttttgtttcgtttgtgctagagggctgatagttcaggaccattcagac
cccatgttcagttcatatgcctataagtcccactacctactgaatgaatcaaatcgtgca
gagttgatgaaattacctatgattccttcttcgtcagcttccaaaaagaaatgtgagaaa
gttattaagactgtttatttgtttcaaggtggaagattgctctgctgtgaatcgtgcccg
gcttccttccacccagaatgcctgagcatagaaatgccagaaggctgctggaattgtaat
gactgtaaagctggcaagaaactacattacaagcagattgtttgggtcaaattgggaaat
tacagatggtggccagcagagatctgcaatcccaggtctgtgccactgaacatccagggc
cttaagcatgacttgggggacttccctgtgttcttctttggttctcatgactactattgg
gtacaccagggcagagtgttcccttatgttgaaggagacaaaagttttgctgagggacag
actagtattaacaagaccttcaaaaaagcactggaagaagctgcaaaacgtttccaggaa
ttgaaagcacaaagagaaagcaaagaagcacttgagattgaaaaaaactcaagaaaaccc
cctccttacaaacacatcaaagctaacaaagtaataggaaaggtgcagatccatgttgca
gacctgtcagagatcccccgctgtaactgcaagcctgctgatgagaacccgtgcggcctg
gagtcggagtgcctaaacaggatgctgcagtacgagtgccacccacaggtgtgcccggct
ggagagcggtgccagaaccagtgctttacaaagaggctctaccctgatgcagaaatcatc
aaaacagaacggagaggctggggcctcaggaccaaaaggagcattaagaagggtgaattt
gtaaatgaatatgtcggtgaattaattgatgaagaagagtgcagattgcgaatcaagcga
gcccacgagaacagtgtaactaatttttatatgttaactgttaccaaggaccgtataatt
gatgctggccccaaaggaaattattctcgctttatgaaccacagttgtaatccaaactgt
gaaacacaaaagtggacagtgaatggagatgttcgagttggactttttgctctttgtgat
attcctgcagggatggagttaacatttaattataacctggattgtctgggcaacggcaga
acggagtgccactgtggagcagagaactgcagcggctttctgggagtgcggccgaagcca
acatgtgcgtcaacaactgaagaaaaggccaaaaatgctaaattaaagcagaagaggcga
aaaatcaaagcagaaccaaagcagatgcacgaagattactgttttcagtgtggagatggt
ggagagctggtcatgtgtgacaaaaaagactgtcccaaagcataccacctcttatgcctt
aacctgactcagccaccgtatggaaagtgggagtgcccgtggcaccagtgcggggagtgc
ggcagcgccgccgtctccttctgcgagttctgcccgcgctccttctgtaaagatcaccga
gagggcgctctggttccctcggccctggaaggccggctctgctgctcggagcacgacccc
gaatctcctgtgtcggcagagtactggagcaagatcaaatgcaagttggaatcgcaggat
cgtggagaagacctgagagaataa
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