Panthera leo (lion): 122219716
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Entry
122219716 CDS
T10741
Symbol
CFB
Name
(RefSeq) complement factor B
KO
K01335
complement factor B [EC:
3.4.21.47
]
Organism
plez Panthera leo (lion)
Pathway
plez04610
Complement and coagulation cascades
plez05150
Staphylococcus aureus infection
plez05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
122219716 (CFB)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
122219716 (CFB)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
122219716 (CFB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122219716 (CFB)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.47 alternative-complement-pathway C3/C5 convertase
122219716 (CFB)
Peptidases and inhibitors [BR:
plez01002
]
Serine peptidases
Family S1: chymotrypsin family
122219716 (CFB)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trypsin
VWA
Sushi
VWA_2
DUF1986
Trypsin_2
Motif
Other DBs
NCBI-GeneID:
122219716
NCBI-ProteinID:
XP_042794257
UniProt:
A0A8C8WSC1
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All DBs
Position
B2:30609529..30615896
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AA seq
768 aa
AA seq
DB search
MGSSLSPQLCLVFLVLGLLSGGGSIPPLTVVGPQGSCSLEGVEIKGGSFRLLKEGQALEY
VCPSGFYPYPVQIRTCRSTGSWSTLRTQDQKIVKTAECRAIRCPRPQEFENGEYWPRTPY
YNLSDEISFRCYDGYTLRGSANRTCQATGRWDGQTAICDDGAGYCPNPGIPLGTRKVGNH
YRLEDRVTYYCNRGLTLRGSQQRTCQEGGSWSGTEPSCQDSFMYDIPEEVAEAFLSSLTE
TIEGVDAEDGHSPGEQQKRKIILDPSGSMNIYLVLDASDSIGIGNFTGAKNCLKDFIEKV
ASYGVKPKYGLVTYATVPKILIRVSDENSSDADWVTRAIDNIDYEDHKLKAGTNTKKALQ
AIYNMMSWPGNQPPEGWNRTRHVIILMTDGLHNMGGDPVSVIHEIRSLLDIGRDRKNLRE
DYLDVYVFGVGPLVNQENINALASKKDKEQHVFKVKDMEDLEDVFKQMLDETRTLGLCGM
VWEHKKGSDYHKQPWQAKISVTRPLKGHETCMGAVVSEYYVLTAAHCFTVDDRNPSIKVS
VGGMKQDLEIDKVLFHPKYDINGKKEEGIPEFYDYDVALIRLKEKLKYGQTLRPICLPCT
QGTNQALRLPLSTTCQQQMEELLPAKDIKALFVSELSKDRKKSLIRKEVYIKNGEKKSSC
ERDAQYALGYDKVKDISKVVTPRFLCTGGVDPYTDPNTCKGDSGGPLIIHKRSRFIQVGV
ISWGVVDVCKDQRRWRQVPAHARDFHINLFQVLPWLREKLKEEDLDFL
NT seq
2307 nt
NT seq
+upstream
nt +downstream
nt
atggggagcagtctcagtccccaactctgcctggtattcttggtgctgggcctcttgtct
ggaggtgggagcataccaccattgactgtggttgggccccaaggctcctgctctctggaa
ggagtagagatcaaaggtggctccttcaggcttctcaaggagggccaggcactggagtat
gtgtgtccctctggcttctacccataccctgtgcagattcgtacctgcagatccacaggg
tcctggagcaccctgcggacccaagaccaaaagattgtcaagacggcagaatgcagagca
attcgctgcccaagaccacaggaatttgagaatggggaatactggccccggaccccctac
tacaatttgagcgatgagatctctttccgctgctatgatggctacactctccggggctct
gccaatcgcacctgccaagcaactggtcggtgggatggacaaacagccatctgcgatgat
ggagcggggtactgccctaacccgggcatcccccttggcacaaggaaggtgggcaaccac
tatcgccttgaagacagagtcacctactactgcaaccggggtctcacccttcgtggctcc
cagcagcgaacatgccaggagggtggctcttggagtggaacagaaccttcctgccaagac
tcctttatgtatgacatccccgaagaggtagccgaagccttcctgtcttccctgacggag
accattgaaggagtagatgctgaggatgggcatagcccaggggaacaacagaagaggaag
attatcctggacccctcgggctccatgaacatctatctggtgttggatgcatcagacagc
attgggatcggcaacttcacaggggccaagaactgtctcaaagacttcattgagaaggtg
gcaagttatggggtgaagccaaaatatggtctagtgacctatgctacagtccccaaaatt
ttgatcagagtgtccgatgaaaacagcagcgatgcagactgggttacaagggcaatcgac
aatatcgactatgaagatcacaagttgaaggcaggcactaacaccaagaaggccctccag
gcaatttacaacatgatgagctggccggggaaccaaccccctgaaggctggaaccgcacc
cgccacgtcatcattctcatgactgatggcttgcacaacatgggtggggacccagtctct
gtcattcatgagatccggagcttgctggacattgggagggatcgcaaaaacctaagggag
gattatctggatgtctatgtgtttggggttgggcctctggtgaaccaagagaacatcaat
gctttggcttccaagaaggataaagaacaacatgtgttcaaagtcaaggacatggaagac
ctggaagatgttttcaaacaaatgcttgatgaaacccggactctgggactctgtggaatg
gtttgggagcacaagaaaggtagtgattaccacaagcaaccgtggcaggccaagatctca
gtcactcgccctttgaaaggacatgagacctgtatgggggccgtggtgtctgagtactac
gtgctgacagcagcacactgtttcacggtggatgatcggaatccttcaatcaaggtcagc
gtgggagggatgaagcaggacttggaaatagataaagtcctatttcaccctaagtacgac
atcaatgggaaaaaagaagaaggcattcctgaattttatgactatgatgtggcccttatc
agactcaaggagaagctcaagtatggccagactctcaggcctatttgtctcccctgcacc
cagggaacaaatcaagctttgaggcttccactgtcaaccacttgccagcaacagatggaa
gagctgctccctgcaaaggatatcaaagctctgtttgtgtcagagttgtccaaagatagg
aagaagtcgctgattcggaaggaggtctacatcaagaacggggaaaagaaatccagctgt
gagagagatgctcaatatgccctaggctatgacaaagtcaaggacatctctaaagtggtc
acccccaggttcctttgcactggaggggtggatccctatactgaccccaacacttgcaaa
ggtgattctggtggtcccctgattattcataagaggagtcgcttcattcaagttggtgtg
atcagctggggtgtagtggatgtctgcaaagaccagaggcggtggcgacaggtacctgct
catgcccgagactttcacatcaacctcttccaagtgctgccctggctcagggagaaactc
aaagaagaggatttggattttctataa
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