Panthera leo (lion): 122225502
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Entry
122225502 CDS
T10741
Symbol
ITK
Name
(RefSeq) tyrosine-protein kinase ITK/TSK
KO
K07363
IL2-inducible T-cell kinase [EC:
2.7.10.2
]
Organism
plez Panthera leo (lion)
Pathway
plez04062
Chemokine signaling pathway
plez04660
T cell receptor signaling pathway
plez04670
Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
122225502 (ITK)
04670 Leukocyte transendothelial migration
122225502 (ITK)
04062 Chemokine signaling pathway
122225502 (ITK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122225502 (ITK)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122225502 (ITK)
Protein kinases [BR:
plez01001
]
Non-receptor tyrosine kinases
TEC family
122225502 (ITK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
PH
SH3_1
BTK
SH3_9
SH3_10
SH3_2
PH_8
SH3_3
SH3_4
ABC1
Motif
Other DBs
NCBI-GeneID:
122225502
NCBI-ProteinID:
XP_042804305
UniProt:
A0A8C8WDW3
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Position
A1:complement(190121997..190181386)
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AA seq
620 aa
AA seq
DB search
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKTSLAYFENRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPMY
HPNFWMDGRWRCCAQLEKLAVGCAQYDPTKNASKKPLPPTPEDNRRSLQEPEETLVIALY
DYQTNDPQELTLQRNEEYYLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNSLETYEWY
NKSISRDKAEKLLLDTAKEGAFMVRDSRTPGTYTVSVFTKAAVSENNPCIKHYHIKETND
NPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIDP
SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRNQRGLFAAETLLGMCLDVCEGMAYLEEACVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASSNIYQIMNHCWKEKPE
DRPPFCRLLSQLAEIAESGL
NT seq
1863 nt
NT seq
+upstream
nt +downstream
nt
atgaacaactttatcctcctagaagaacagctcatcaagaaatcgcaacaaaagagaaga
acttctccctccaactttaaagtccgcttctttgttttaaccaaaaccagcctggcgtac
tttgagaatcgtcatgggaaaaagcgcacattgaagggctccattgaactctcccgaatc
aaatgcgttgagattgtgaaaagtgacattagtatcccatgccactataaatatccattt
caggttgtgcatgacaattacctcctgtatgtgtttgctccagaccgtgagagccggcaa
cgctgggttctggcccttaaagaagaaacaaggaacaataacagtttggtacccatgtat
catcctaacttctggatggatgggaggtggaggtgctgtgctcagctggagaagctcgca
gtgggctgtgcccagtacgatccaaccaagaatgcttcaaagaagcctcttcctcctact
cctgaagacaacaggcgatcactccaggaacctgaagaaacccttgtcattgccttgtat
gactaccaaacgaatgacccacaggaacttacgttacaacgcaatgaggaatactacctg
ctggacagttccgagattcactggtggagagtgcaggacaggaatgggcatgaaggatat
gtaccaagcagttatctggtggaaaagtctccaaatagcctggaaacctatgagtggtac
aataagagtatcagccgagacaaagctgaaaaacttcttttggacacagccaaagaagga
gccttcatggtacgagattccaggactccaggaacttacaccgtgtctgttttcactaaa
gccgctgtaagtgagaacaacccctgtatcaagcattatcacatcaaggaaactaatgat
aaccccaaacgatattatgtggctgaaaagtatgtgtttgattccatccctctcctcatc
aattaccaccaacacaatggaggaggtctggtcactcgactccggtatccagtttgttcc
tggaggcagaaagccccagtcacagcaggactgagatatgggaaatgggtgattgatccc
tcagagctcacttttgtacaggaaattggcagtgggcagtttgggttggtgcatctcggc
tactggctcaacaaggacaaggtggccatcaaaaccattcaagaaggggctatgtcggaa
gaggacttcatagaggaggctgaagtcatgatgaaactctctcaccccaaactggtgcag
ctgtatggggtatgcctagagcaggcccccatctgcctggtgtttgagttcatggagcac
ggctgcctgtcggattacctgcgcaaccagcgaggactctttgctgcagaaaccctgctg
ggcatgtgcctggacgtgtgtgagggcatggcctacctggaagaggcatgtgtcatccac
agagacctggctgccagaaattgtttagtgggagaaaaccaagtcatcaaggtgtccgac
tttgggatgacaaggttcgttcttgatgaccaatacaccagttccacaggcaccaagttc
ccagtgaagtgggcatccccggaagtcttctccttcagtcgctatagcagcaagtcagat
gtgtggtcatttggtgtgctgatgtgggaagtcttcagtgaaggcaaaatcccgtatgaa
aaccgaagcaactcagaggtggtggaagatatctctactggatttcgcttatacaagccc
cggctggcctcctcaaatatctaccagatcatgaatcattgctggaaagagaaaccagaa
gaccggccacctttctgcagactcttgagtcaactggctgaaattgcagaatcaggactt
tag
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