Panthera leo (lion): 122226074
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Entry
122226074 CDS
T10741
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04010
MAPK signaling pathway
plez04012
ErbB signaling pathway
plez04020
Calcium signaling pathway
plez04151
PI3K-Akt signaling pathway
plez05014
Amyotrophic lateral sclerosis
plez05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122226074 (ERBB4)
04012 ErbB signaling pathway
122226074 (ERBB4)
04020 Calcium signaling pathway
122226074 (ERBB4)
04151 PI3K-Akt signaling pathway
122226074 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
122226074 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122226074 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122226074 (ERBB4)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122226074 (ERBB4)
Protein kinases [BR:
plez01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
122226074 (ERBB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
DUF3951
ABC1
Motif
Other DBs
NCBI-GeneID:
122226074
NCBI-ProteinID:
XP_042804638
LinkDB
All DBs
Position
C1:complement(195132102..195844534)
Genome browser
AA seq
1302 aa
AA seq
DB search
MHKTESRVLATWGFGGDYQSKVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEIT
SIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVFLNYRKD
GNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVSTNGSSGC
GRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDC
FACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVR
ACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNL
IFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGR
VLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIV
IRDNRKAENCTAAGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRSCIESCNLYDGEFREF
ENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFK
YADQDRECHPCHPNCTQGCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVI
VGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGS
GAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGV
CLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAA
RNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSY
GVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPK
FKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQ
AFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVPYRATTS
TIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVPEDSSTQRYSADPTVFAPERSPRGELD
EEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEP
LYLNTFANALGNAGYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKY
FYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq
3909 nt
NT seq
+upstream
nt +downstream
nt
atgcataaaacagagagtagagtgttagctacctggggcttcgggggagattaccaatca
aaggtgtgtgcagggacagagaacaagctgagctctctctctgacctggagcagcagtat
cgagccttgcgcaaatactatgagaactgtgaggtggtcatgggcaacctggagataacc
agcatcgagcacaaccgggacctctcctttctgcggtctattcgagaagttacaggctac
gtgttagtggctcttaatcagtttcgctacctgcctctggagaatttacgcattatccgt
ggaacaaaactttatgaggatcgatatgccttggcagtatttttaaactacagaaaagat
gggaactttggacttcaagaacttggactaaagaacttgacagaaatccttaatggtgga
gtctatgtagaccagaacaaatttctttgttacacagacacaattcattggcaagatatt
gttcggaatccgtggccttccaacttgactctggtgtcaacaaacggtagctcaggatgt
ggacgttgccataagtcctgtactggccgatgctggggacccacagaaaatcattgccag
accttgacaaggacggtgtgtgcagaacagtgtgacggcaggtgctatggaccctacgtc
agtgactgctgtcatagagaatgtgctggaggttgctcaggaccaaaagacaccgactgc
tttgcctgcatgaatttcaatgacagtggagcgtgtgttactcaatgtccccaaactttt
gtctacaatccaaccacttttcagctggaacataacttcaatgcaaagtatacatatgga
gcattttgtgtcaagaaatgcccacataactttgtggtggattccagttcttgtgtgcgt
gcctgccctagttccaagatggaagtggaagaaaatgggattaaaatgtgtaaaccttgc
actgatatttgcccaaaagcttgtgatggcattggcacaggatcactgatgtcagctcag
accgtggattccagtaacattgacaaattcataaactgcaccaaaatcaatgggaatttg
atcttccttgtcactggtattcatggggacccttacaatgcaattgaagccatagaccca
gagaaactgaatgtctttcggaccgttcgagagataacaggtttcttgaacatacagtca
tggcctccaaacatgactgacttcagtgttttttctaacctggtgaccattggtggaaga
gtactctacagtggcctctccttgcttatcctcaaacaacagggcatcacttctctacaa
ttccagtccctgaaggaaatcagtgcaggaaacatctatattactgacaacagcaaccta
tgttattatcataccattaattggacaacactcttcagcactatcaaccaaagaatagtg
atccgggacaacagaaaagctgaaaactgtactgctgcaggaatggtgtgcaaccatctg
tgttcaagtgatggctgctggggacctggcccagaccaatgcctgtcctgccgtcgcttc
agcagaggaaggagctgcatagagtcttgtaacctctatgatggtgaatttcgagagttt
gagaatggctccatctgtgtggagtgtgacccccagtgcgagaagatggaagacggcatc
ctcacatgccatggaccgggacctgataactgcacaaagtgttcccattttaaggatggc
ccgaactgtgtggaaaaatgtccagatggcttgcagggggcaaacagtttcattttcaag
tatgctgatcaggatcgagagtgccatccatgccatccaaactgcacccaagggtgtagc
ggccccactagtcatgactgcatttactatccttggacgggccattccactttaccacaa
catgctagaactcctctaattgcagctggagtcatcggcgggctcttcatcctggtcatc
gtgggtctaacatttgcagtttatgtaagaaggaagagtatcaaaaagaaaagagccctg
agaagatttctggaaacagagttggtagaacccttaactcccagcggcacagcacccaat
caagctcaactgcgtattttaaaagaaactgagctcaaaagagtgaaagtacttggctcg
ggagcttttggaacagtgtataaaggtatttgggtacctgaaggagaaacagtaaagatt
cctgtggctattaagattcttaatgaaacaactggtcccaaagccaatgtggagttcatg
gatgaagctttgatcatggcaagtatggaccatccacacttagtccggttattgggtgtg
tgtctgagcccaaccattcaactggttacacagcttatgccccatggctgcctgttggat
tatgtacatgaacataaggataacattggatcccagctactgcttaactggtgtgtccaa
atagctaagggaatgatgtacctggaggaaagacggcttgttcatcgggatttggcagcc
cgaaatgtcttagtgaaatctccaaaccatgtgaaaatcacagattttggactagctagg
ctcttagaaggagatgaaaaagagtataatgctgatggaggaaagatgccaattaaatgg
atggctctggagtgtatacactacaggaagttcacccatcagagtgatgtttggagttat
ggagttaccatatgggaactgatgacctttggaggaaaaccctatgatggaattccaacc
agagaaatcccggatttattagagaaaggagaacgtttgccccagcctcctatctgcact
attgacgtttacatggtcatggtcaaatgctggatgattgatgcagacagtagacctaaa
tttaaggaactggctgctgaattttcgaggatggctcgagaccctcaaagatatctagtt
attcagggtgatgatcgcatgaagcttcccagtccaaatgacagcaagttctttcagaat
ctcttggatgaagaggacctggaagatatgatggatgctgaggaatacctggtccctcag
gctttcaacatcccacctcccatctatacttccagagcaagaattgactcaaataggagt
gaaattggacacagccctcctcctgcctacacccccatgtcaggaaaccagtttgtatac
cgagacggggggtttgctgcagagcaaggagtgcctgtgccgtacagagccacgaccagc
acaatcccagaagctccagttgctcagggggctacagccgagatttttgatgactcctgc
tgcaacggcaccctacgcaagccagtggcaccccacgttccagaggatagcagcacccag
aggtacagcgccgaccccacggtgtttgccccagaacggagcccacgaggagagctggat
gaagaaggttacatgacccctatgcgagataaacctaaacaagaatacctgaaccctgtg
gaagaaaacccttttgtttctcggagaaaaaatggagaccttcaagctttggataatccc
gaatatcacaatgcttccaacggtccacccaaggcagaggatgagtatgtgaatgagcca
ctgtacctcaacacctttgccaacgcgttgggaaatgccgggtatctgaagaacaatgta
ctgtctgtgccagaaaaggccaagaaagcattcgacaaccctgactactggaatcacagc
ctgccaccccggagcacccttcagcacccagactacctgcaggagtacagcacaaaatat
ttttataaacaaaatggacggatccggcctattgtggcagagaatcctgaatacctctct
gagttctcgctgaagccaggcaccgtgctgcctcctccaccctacagacaccgaaacact
gtggtgtaa
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integrated database retrieval system
