Panthera leo (lion): 122226564
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Entry
122226564 CDS
T10741
Symbol
PIKFYVE
Name
(RefSeq) 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1
KO
K00921
1-phosphatidylinositol-3-phosphate 5-kinase [EC:
2.7.1.150
]
Organism
plez Panthera leo (lion)
Pathway
plez00562
Inositol phosphate metabolism
plez01100
Metabolic pathways
plez04070
Phosphatidylinositol signaling system
plez04145
Phagosome
plez04810
Regulation of actin cytoskeleton
Brite
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.150 1-phosphatidylinositol-3-phosphate 5-kinase
122226564 (PIKFYVE)
Membrane trafficking [BR:
plez04131
]
Endocytosis
Macropinocytosis
Kinases
122226564 (PIKFYVE)
Endosome - Golgi transport
Others
Others
122226564 (PIKFYVE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122226564
NCBI-ProteinID:
XP_042805900
LinkDB
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Position
C1:192517482..192604908
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AA seq
2111 aa
AA seq
DB search
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERV
EGGQGEQPSLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSAVLEENSLQHPQENT
DTRRKAEPAFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDC
SEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSN
SIGEDLNALSDSASSVSVLDPNEPRTPVGSRKASRNIFLEDDFAWQSLIHPDSSNTPLST
RLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVSSYETSVSPQSNRTYVRTETTEDERK
ILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAI
AIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWF
KDIKFDDSDTEQIAEEGDDNLTNSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFH
IKKPSKYPHVPPHPADQKEYLISDNGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGW
HHNNLELLREENGEKQAMERLLSANHNHMMALLQQLLHNESLSPSWRDIIVSLVCQVVQT
VRPDVKNRDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLL
KCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEH
GITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMF
FEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLTQNP
SFHSLIEGREDEGTAQEPFSGSPLPREPDFPPEFLPSDDSSLLESRIVFEKGDQENRSIP
QDVACLKHQEYATTACPAGIPCALFPSVPESLLPLHVDDQQDAVGLEQPEALQHPDELQD
PKSQMRAFRDPLQDDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFL
LTEKGMRCSTRDYFAEQVYWSPLLNKEFKEVESRRKKQLLRDLSGLQGMNGSVQAKAIQV
LPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQQKNADPFAHSKDVPGTSSGRSGSK
TDGDEEKGLIPSDAVWSTKVDCLNPVNHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFY
GKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQ
HTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDY
HQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYLAV
DERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWVEKMQARLMSSSADAPQQLQSIF
ESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDAAPRN
ISPGLQNGEKEDRFLTTLSSQSPASSAHLQLPTPPEALPEQLAGAPPELDTASSSEDVFD
GHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEP
SSIIAFALSCKEYRNALEELSKVTQRNSAEEGLPTNSTLDSRPKSSSPIRLPEVSGGQTN
RTAEAEPQPTKKTSGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQG
AESQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILGSSEEDFIR
SLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRP
TALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGK
ESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRASIRSDSHFLSSHLIIDYSLLVGRDDTS
NELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMV
PDHWTGLGLNC
NT seq
6336 nt
NT seq
+upstream
nt +downstream
nt
atggccacagatgataagacttccccaacattggactcggctaatgatttgcctcgatct
cctactagtccttctcatctcacacactttaaacctttgactcctgatcaggacgaacct
ccttttaaatcagcgtatagttcttttgtaaatctctttcgatttaacaaagagcgagtg
gaagggggccagggagagcagccctctctaagtggaagttggaccagccctcagctccct
tcaagaacacagtctgtgaggtcacctacaccttataaaaaacagcttaatgaggaactc
cagcggcgatcttcagcagtattagaagagaacagtttgcaacatccccaggagaataca
gacacaagaaggaaagcagagcctgcctttggaggtcatgaccctcgtacagctgttcag
cttcgaagcctcagcacagtattaaaacgcctcaaggaaatcatggaggggaaaagccag
gatagcgacctgaagcaatactggatgccagacagccaatgtaaagagtgctacgactgt
agtgagaaatttacaacctttaggcgcagacaccattgccgcttgtgtgggcagattttt
tgcagtcgttgctgtaatcaagaaatccctggaaaatttatgggctatacgggggacctc
cgagcttgcacatactgtagaaaaatagccttaagttatgctcattccacagacagtaat
tccattggggaagacttgaatgctctttcagattctgcttcctctgtgtctgtacttgat
ccaaatgaacctcgaacacctgttggaagtagaaaagccagccgcaacatatttttggag
gatgattttgcttggcaaagtttgattcatccagactcctcaaatactcctctttcaaca
aggcttgtatctgttcaagaagatgctgggaagtctcctgctcgaaatagatcagccagc
attactaacctgtcactggatcgatctggctctcccatggtgtcttcatatgagacatct
gtcagtccccagtctaaccggacatacgttaggacagagaccactgaggatgaacgcaaa
attcttctggacagtgttcagttaaaggacctgtggaagaaaatctgccatcatagtagt
ggaatggagtttcaggatcaccgttactggctgagaacgcatcccaactgcattgtggga
aaagaattagtcaactggttgatccgaaatgggcacattgctacaagggcacaagctata
gcaatcggacaagccatggtcgatggacgttggctggactgtgtcagtcatcacgaccag
cttttcagggatgagtatgcgctgtacaggccattgcagagtacagaattttccgagacc
ccttctccagacagtgactctgtgaactctgtggaaggacactctgagccatcgtggttt
aaagacataaagtttgatgacagtgacacggaacagatagctgaagaaggtgacgataat
ttgactaattctgccagtcctagcaagcgcacatcagtcagcagtttccagtccacagtg
gacagtgactcagccgcgtccatcagcctgaacgtggagctggacaacgtgaacttccat
atcaagaagccctccaagtacccacatgtgccccctcaccctgctgaccaaaaagagtat
ttgatatctgacaatggaggacaacaactctcaataagtgacgccttcatcaaagaatcc
ttatttaatcgtcgagttgaggaaaaatccaaagagctgcctttcacacctttgggttgg
catcataacaacctggagctgctgagggaggagaatggagagaaacaagccatggagagg
ttgctctcagctaatcacaaccacatgatggcactactccagcagttgctccataatgag
tcattgtcaccatcttggagggacatcattgtatcactggtctgccaggttgttcagaca
gtccgacctgatgtcaagaaccgggatgatgacatggacatccgtcagtttgtccatatt
aaaaaaattccaggtggaaagaagtttgattctgtggttgtcaatggatttgtttgtacc
aaaaatattgcacataaaaagatgaattcttgtattaaaaatcccaaaattcttctgttg
aaatgttccatcgagtatctctacagagaagaaactaaatttacctgcattgatcctatt
gtgcttcaggaaagggaattcttgaagaattatgttcagcgaatagttgatgttcgacct
acattggttctagttgaaaaaacagtgtctcggattgcccaagacatgttactagaacat
ggcattactttggtcattaatgtaaaatcacaagttttagaacgaatcagtcggatgacc
caaggtgatttagtaatgtcgatggaccagctgcttacaaaaccccacctgggcacctgt
cacaaattttatatgcagatctttcagttgcctaatgagcaaaccaaaacactgatgttt
tttgaaggctgtccacagcacctgggctgtacaatcaagcttagaggaggctctgattat
gagctggctcgagttaaagagatcctaatatttatgatctgtgtagcttatcattctcaa
ctagaaatctccttcctcatggatgaatttgctatgcctcctacgttaacacaaaaccct
tccttccattctctgattgaggggcgggaggatgaagggaccgcacaagagccgttcagc
ggaagtcccctcccccgggagcctgactttcctccagaatttctgccctccgatgatagc
agtttgctagaatcaaggattgtgtttgagaagggtgaccaggagaatagaagcattcca
caggatgttgcctgtttgaagcatcaagagtatgccacaacggcttgccctgcagggatc
ccctgtgctctctttccatcggtcccagaatcgttgttgccgctccacgtggacgaccag
caggatgctgtgggcttggagcagccggaggctttgcagcacccagatgagctacaggat
cccaaaagccagatgagagcctttagagaccctttgcaggatgacactggattgtatgtt
actgaggaggttacctcttctgaagataaacgaaagacttattctttggcctttaaacag
gaattgaaagatgtgatcctctgtatctccccagtgatcacattccgggagcccttcctt
ttaactgaaaaagggatgagatgctctactcgagattatttcgcagagcaggtttactgg
tctcctctcctcaataaagagttcaaagaagtggaaagcaggcggaagaagcagctgctt
agggatctctctggtcttcaaggcatgaacggaagtgttcaggccaaggctattcaagtc
ttgccctcgcacgagctagtgagcactagaattgctgagcatcttggggatagccagagc
ttgggtagaatgctggctgattatcgggccagaggaggaagaattcagcaaaaaaatgca
gacccttttgctcattcaaaggatgtacctggtacttcaagtggcagatcaggaagcaaa
actgatggtgacgaggagaaagggttgattccgagtgatgcagtgtggtcgacaaaggtg
gactgtctgaaccctgttaaccaccagagactgtgcgtgctcttcagcagctcttctgcc
cagtccagcaatgcccccagtgcctgtgtcagcccttggattgtaacaatggaattttat
ggaaagaatgatcttacattaggcatatttttagagagatactgtttcaggccttcttat
cagtgtcctagcatgttctgtgatacccccatggtgcatcatattcggcgctttgtccat
ggccaaggctgtgtgcagataattctgaaggagttagattctccagtacctggatatcaa
catacaattcttacctattcctggtgcagaatctgcaaacaggtaacaccagttgttgct
ctttccaacgagtcctggtccatgtcatttgcaaaataccttgaacttaggttttatggg
caccagtacactcgcagagccaatgctgagccgtgtggtcactccatccaccatgattat
caccagtatttctcctataatcagatggtggcatccttcagttattctcccattcggctt
cttgaagtatgtgttcctctccctaagatattcattaaacgtcaggccccattaaaagtg
tcccttcttcaggatctaaaggacttctttcaaaaagtttcacaggtatatcttgctgtt
gatgaaagacttgcatctttgaaaaccgatacgtttagcaaaacaagagaggaaaaaatg
gaagatatctttgcacaaaaagagatggaggaaggcgagttcaagaactgggtggagaag
atgcaagccaggctcatgtcctcctccgcggacgccccacagcagctgcagtctatcttc
gagtccctcattgccaagaagcagagtctgtgtgaagtgcttcaggcttggaacaacaga
ttgcaggaccttttccagcaggaaaagggtagaaagcgaccttcagttcctccaagtcct
ggaagactgagacagggggaagaaagcaagataagcgcaatggatgcggctccacgaaat
atttctccaggacttcaaaacggagaaaaagaggaccgcttcctgaccaccctgtccagc
cagagccccgccagctcggcgcatctgcagctgcctacccccccggaagccctgcccgag
cagctggcgggagcgccccctgagctcgatacagccagcagttccgaagatgtgtttgat
ggacatttgctgggatccacagacagccaggtgaaggaaaaatcaaccatgaaagccatc
tttgcaaatttgcttccaggaaatagctacaaccctattccatttccgtttgatccagat
aaacactacttaatgtatgaacacgaacgggtacccattgctgtttgtgagaaggagccc
agctccatcattgcttttgctctcagttgtaaagaataccgaaatgccttagaggaatta
tccaaagtgactcagcggaacagtgctgaagaagggcttccaacaaatagtactttggac
agccgaccaaagagcagcagccctattagattacctgaggtcagcggaggacagacaaac
cgtacagcagaagcagaaccacagccaaccaaaaagacttctggaatgctgtccttcttc
cgagggacagcagggaaaagccctgatctctcttcccagaaaagagagaccttacgtgga
gcagacagtgcttactaccaggttgggcagacgggcaaggaggggacggagaatcaaggt
gctgagtctcaagatgaggtagatggaggagatacacaaaagaaacaactcataaatcct
cacgtggaactacaattttctgacgcgaatgccaagttttactgtcggctctactatgcg
ggagagtttcataagatgcgtgaggtgattctggggagcagtgaagaagatttcattcgt
tctctttcccactcgtcgccctggcaggcccgtgggggcaaatcaggagctgccttctat
gccacggaagatgatagattcattttgaagcagatgcctcgtctggaagtccagtctttc
ctcgactttgcaccacactacttcaattatattacaaatgctgttcaacaaaagaggccc
actgcattggccaaaattcttggagtttacagaattggttataagaattctcagaacaat
actgagaagaagttagatctccttgtcatggaaaatcttttctatgggagaaagatggca
caggtttttgatttgaagggttcacttaggaatagaaatgtaaaaactgatactgggaaa
gagagctgtgatgtagtcctgctggatgaaaatctcttaaagatggttcgagacaacccc
ctgtatatccgttctcattccaaagccgtgctgagagcctcgatccgtagtgattcccac
ttcctttctagccacctcattatagattattctttgctggttggacgagatgataccagc
aatgagctggtagtcggaattatagattatattcgaacatttacatgggacaaaaagctt
gagatggttgtgaaatcaacaggaattttagggggacaaggtaaaatgcccaccgtggtc
tctccagagttgtacaggactagattttgtgaagcaatggacaagtacttcctgatggta
ccagaccactggacaggcttaggtctgaactgctga
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integrated database retrieval system
