Panthera leo (lion): 122227112 Help Entry 122227112         CDS       T10741                                  Symbol CASP9 Name (RefSeq) caspase-9   KO K04399   caspase 9 [EC:3.4.22.62] Organism plez  Panthera leo (lion) Pathway plez01524   Platinum drug resistance plez04115   p53 signaling pathway plez04151   PI3K-Akt signaling pathway plez04210   Apoptosis plez04215   Apoptosis - multiple species plez04370   VEGF signaling pathway plez04919   Thyroid hormone signaling pathway plez05010   Alzheimer disease plez05012   Parkinson disease plez05014   Amyotrophic lateral sclerosis plez05016   Huntington disease plez05020   Prion disease plez05022   Pathways of neurodegeneration - multiple diseases plez05134   Legionellosis plez05145   Toxoplasmosis plez05152   Tuberculosis plez05160   Hepatitis C plez05161   Hepatitis B plez05162   Measles plez05163   Human cytomegalovirus infection plez05164   Influenza A plez05167   Kaposi sarcoma-associated herpesvirus infection plez05168   Herpes simplex virus 1 infection plez05169   Epstein-Barr virus infection plez05170   Human immunodeficiency virus 1 infection plez05200   Pathways in cancer plez05210   Colorectal cancer plez05212   Pancreatic cancer plez05213   Endometrial cancer plez05215   Prostate cancer plez05222   Small cell lung cancer plez05223   Non-small cell lung cancer plez05416   Viral myocarditis plez05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:plez00001]  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     122227112 (CASP9)    04151 PI3K-Akt signaling pathway     122227112 (CASP9)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     122227112 (CASP9)    04215 Apoptosis - multiple species     122227112 (CASP9)    04115 p53 signaling pathway     122227112 (CASP9)  09150 Organismal Systems   09152 Endocrine system    04919 Thyroid hormone signaling pathway     122227112 (CASP9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122227112 (CASP9)   09162 Cancer: specific types    05210 Colorectal cancer     122227112 (CASP9)    05212 Pancreatic cancer     122227112 (CASP9)    05215 Prostate cancer     122227112 (CASP9)    05213 Endometrial cancer     122227112 (CASP9)    05222 Small cell lung cancer     122227112 (CASP9)    05223 Non-small cell lung cancer     122227112 (CASP9)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     122227112 (CASP9)    05161 Hepatitis B     122227112 (CASP9)    05160 Hepatitis C     122227112 (CASP9)    05164 Influenza A     122227112 (CASP9)    05162 Measles     122227112 (CASP9)    05168 Herpes simplex virus 1 infection     122227112 (CASP9)    05163 Human cytomegalovirus infection     122227112 (CASP9)    05167 Kaposi sarcoma-associated herpesvirus infection     122227112 (CASP9)    05169 Epstein-Barr virus infection     122227112 (CASP9)   09171 Infectious disease: bacterial    05134 Legionellosis     122227112 (CASP9)    05152 Tuberculosis     122227112 (CASP9)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     122227112 (CASP9)   09164 Neurodegenerative disease    05010 Alzheimer disease     122227112 (CASP9)    05012 Parkinson disease     122227112 (CASP9)    05014 Amyotrophic lateral sclerosis     122227112 (CASP9)    05016 Huntington disease     122227112 (CASP9)    05020 Prion disease     122227112 (CASP9)    05022 Pathways of neurodegeneration - multiple diseases     122227112 (CASP9)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     122227112 (CASP9)    05416 Viral myocarditis     122227112 (CASP9)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     122227112 (CASP9)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:plez01009]     122227112 (CASP9)    01002 Peptidases and inhibitors [BR:plez01002]     122227112 (CASP9) Enzymes [BR:plez01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.62  caspase-9      122227112 (CASP9) Protein phosphatases and associated proteins [BR:plez01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      122227112 (CASP9) Peptidases and inhibitors [BR:plez01002]  Cysteine peptidases   Family C14: caspase family    122227112 (CASP9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 CARD Motif Other DBs NCBI-GeneID:  122227112 NCBI-ProteinID:  XP_042807288 LinkDB All DBs Position C1:complement(11164443..11183270) Genome browser AA seq 451 aa AA seqDB search MDEADRRLLRRCRVRLVGELQVASLWDALLTRQLFTPAMIEDIQHAGSGSRSDQVRQLVI DLETRGSQALPLFISCLEDTGQDALASLLRMGRQAEKQNPQAVRPLDLMPVVVGPMGLKP EELRRRQYPLKPTPEKLTPVVLGPEELWPAKLRPEVLRPEVPRPVDIGSGPFSDICAQEI SKRNADLAYVLNADPCGHCLIINNMNFCLESRLQTRTGSNIDCEKLQRRFSLLHFVVEVK HDQTAKQMVQVLVELARRDHGALDCCVVVILSHGCQASHRQFPGAVYGTDGCPVSIEKIV NIFNGSGCPSLGGKPKLFFIQACGGERKDHGVEVASTSPEDRTPGSDSEPDAVPFQEGPV TFDQPDAVSSLPTPSDIFVSYSTFPGFVSWRDTKSGSWYVETLDGVFEQWARSEDLQTLL LRVANAVSQKGIYKQIPGCFNFLRKKLYFKM NT seq 1356 nt NT seq  +upstreamnt  +downstreamnt atggacgaggctgaccggcggctcctgcggcggtgccgggtgcggctggtcggcgagctg caggtggcctcgctctgggacgctctgctgacccgccagctcttcacgcccgcgatgatc gaggacatccagcatgcgggctcagggtctcggagcgatcaggtcaggcagcttgtcata gatctagagacccgagggagtcaggcccttcctttgttcatctcctgcttagaggacaca ggccaggatgcgctggcttcattgctgagaatgggtcggcaagcagaaaagcagaatcca caggccgtcagacccctggacctcatgcctgtggtggttggaccaatgggcctcaaacca gaggagctcagaaggaggcagtatcctttaaagccgactccggaaaaactcactccagtg gtgttggggcccgaggagctgtggccagccaagctgcggccagaggttctcagaccagag gtgcctaggccagtggacattggttctggaccattcagtgatatctgtgctcaggaaatt tcgaagcgaaatgctgatttggcgtatgtcctgaacgcggacccctgtggccactgcctc atcatcaacaacatgaacttctgcctcgagtcgaggctccagacccgtaccggctccaat atcgactgtgagaagttgcagcgacgtttctccctgctgcatttcgtggtggaggtgaag cacgaccagacggccaagcaaatggtccaggtgttggtggagctggcgcggcgggaccac ggtgctctggactgctgcgtggtggtcatcctctctcacggctgtcaggccagccaccgc cagttcccaggggctgtttatggcacagatggctgtcctgtgtccatcgagaaaattgtg aacatcttcaatggatccggctgccccagcttgggagggaagcccaagctcttctttatc caggcctgtggtggcgagcggaaagaccatggggttgaggtggcctccacgtcccctgaa gacaggacccctggcagtgactccgagccagacgctgtcccgttccaggaaggcccagtc acctttgaccagccggacgccgtgtctagcttgcccacacccagtgacatctttgtgtcc tactccaccttcccaggttttgtttcctggagggacaccaagagcggctcctggtacgtg gagaccttggatggtgttttcgagcagtgggctcgctctgaggacctgcagaccctcctg ctcagggtcgctaatgctgtttcgcagaaagggatttacaagcagattcctggttgtttc aatttcctccggaaaaaactttactttaaaatgtaa

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