Panthera leo (lion): 122228354
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Entry
122228354 CDS
T10741
Symbol
ADCY2
Name
(RefSeq) adenylate cyclase type 2 isoform X1
KO
K08042
adenylate cyclase 2 [EC:
4.6.1.1
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
plez01522
Endocrine resistance
plez04015
Rap1 signaling pathway
plez04020
Calcium signaling pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04062
Chemokine signaling pathway
plez04072
Phospholipase D signaling pathway
plez04081
Hormone signaling
plez04082
Neuroactive ligand signaling
plez04114
Oocyte meiosis
plez04211
Longevity regulating pathway
plez04213
Longevity regulating pathway - multiple species
plez04261
Adrenergic signaling in cardiomyocytes
plez04270
Vascular smooth muscle contraction
plez04371
Apelin signaling pathway
plez04540
Gap junction
plez04611
Platelet activation
plez04713
Circadian entrainment
plez04714
Thermogenesis
plez04723
Retrograde endocannabinoid signaling
plez04724
Glutamatergic synapse
plez04725
Cholinergic synapse
plez04727
GABAergic synapse
plez04750
Inflammatory mediator regulation of TRP channels
plez04911
Insulin secretion
plez04912
GnRH signaling pathway
plez04913
Ovarian steroidogenesis
plez04914
Progesterone-mediated oocyte maturation
plez04915
Estrogen signaling pathway
plez04916
Melanogenesis
plez04918
Thyroid hormone synthesis
plez04921
Oxytocin signaling pathway
plez04922
Glucagon signaling pathway
plez04923
Regulation of lipolysis in adipocytes
plez04925
Aldosterone synthesis and secretion
plez04926
Relaxin signaling pathway
plez04927
Cortisol synthesis and secretion
plez04928
Parathyroid hormone synthesis, secretion and action
plez04934
Cushing syndrome
plez04935
Growth hormone synthesis, secretion and action
plez04970
Salivary secretion
plez04971
Gastric acid secretion
plez04972
Pancreatic secretion
plez04976
Bile secretion
plez05032
Morphine addiction
plez05163
Human cytomegalovirus infection
plez05166
Human T-cell leukemia virus 1 infection
plez05200
Pathways in cancer
plez05207
Chemical carcinogenesis - receptor activation
plez05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122228354 (ADCY2)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
122228354 (ADCY2)
04371 Apelin signaling pathway
122228354 (ADCY2)
04020 Calcium signaling pathway
122228354 (ADCY2)
04072 Phospholipase D signaling pathway
122228354 (ADCY2)
04024 cAMP signaling pathway
122228354 (ADCY2)
04022 cGMP-PKG signaling pathway
122228354 (ADCY2)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
122228354 (ADCY2)
04081 Hormone signaling
122228354 (ADCY2)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
122228354 (ADCY2)
09144 Cellular community - eukaryotes
04540 Gap junction
122228354 (ADCY2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
122228354 (ADCY2)
04062 Chemokine signaling pathway
122228354 (ADCY2)
09152 Endocrine system
04911 Insulin secretion
122228354 (ADCY2)
04922 Glucagon signaling pathway
122228354 (ADCY2)
04923 Regulation of lipolysis in adipocytes
122228354 (ADCY2)
04912 GnRH signaling pathway
122228354 (ADCY2)
04913 Ovarian steroidogenesis
122228354 (ADCY2)
04915 Estrogen signaling pathway
122228354 (ADCY2)
04914 Progesterone-mediated oocyte maturation
122228354 (ADCY2)
04921 Oxytocin signaling pathway
122228354 (ADCY2)
04926 Relaxin signaling pathway
122228354 (ADCY2)
04935 Growth hormone synthesis, secretion and action
122228354 (ADCY2)
04918 Thyroid hormone synthesis
122228354 (ADCY2)
04928 Parathyroid hormone synthesis, secretion and action
122228354 (ADCY2)
04916 Melanogenesis
122228354 (ADCY2)
04925 Aldosterone synthesis and secretion
122228354 (ADCY2)
04927 Cortisol synthesis and secretion
122228354 (ADCY2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
122228354 (ADCY2)
04270 Vascular smooth muscle contraction
122228354 (ADCY2)
09154 Digestive system
04970 Salivary secretion
122228354 (ADCY2)
04971 Gastric acid secretion
122228354 (ADCY2)
04972 Pancreatic secretion
122228354 (ADCY2)
04976 Bile secretion
122228354 (ADCY2)
09156 Nervous system
04724 Glutamatergic synapse
122228354 (ADCY2)
04727 GABAergic synapse
122228354 (ADCY2)
04725 Cholinergic synapse
122228354 (ADCY2)
04723 Retrograde endocannabinoid signaling
122228354 (ADCY2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
122228354 (ADCY2)
09149 Aging
04211 Longevity regulating pathway
122228354 (ADCY2)
04213 Longevity regulating pathway - multiple species
122228354 (ADCY2)
09159 Environmental adaptation
04713 Circadian entrainment
122228354 (ADCY2)
04714 Thermogenesis
122228354 (ADCY2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122228354 (ADCY2)
05207 Chemical carcinogenesis - receptor activation
122228354 (ADCY2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122228354 (ADCY2)
05163 Human cytomegalovirus infection
122228354 (ADCY2)
09165 Substance dependence
05032 Morphine addiction
122228354 (ADCY2)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
122228354 (ADCY2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
122228354 (ADCY2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
122228354 (ADCY2)
Enzymes [BR:
plez01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
122228354 (ADCY2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
HNOBA
Motif
Other DBs
NCBI-GeneID:
122228354
NCBI-ProteinID:
XP_042809295
LinkDB
All DBs
Position
A1:complement(232909321..233322187)
Genome browser
AA seq
1097 aa
AA seq
DB search
MWREAMRRRRYLRDRAEAAAAAAAAAAGGGDGLQRSRDWLYESYYCMSQQHPLIVFLLLI
VMGACLALLAVFFALRLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVI
WMCLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTASSHTVVL
SICLSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKL
EFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILY
ADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPN
HAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLA
NHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSP
HLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHN
FQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKILEKEYRA
TALPAFKYYVTCACLILFCIFVVQILVLPKTSILGISFGAAFLLLACILFVCFAGQLLQC
SKKASASLLWLLKSSSIIADRPWPRVSLTVLTTAIILTMAVFNMFFLSDPEEAMPPPANT
SNTSLSALNNQAVILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALIGYN
TILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLW
KNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIP
DFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAV
PSQEHTQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQ
KPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGELKTY
FVNTEMSRSLSQSNVAS
NT seq
3294 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgggaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggcggcggct
gcggcggcggcggcggcggcgggcggcggcgacgggctgcagcggtcccgggactggctg
tacgagtcctactactgcatgagccagcagcacccgctcatcgtcttcctgctgctcatc
gtcatgggcgcctgcctcgccctgctcgccgtcttcttcgcgctccggctggaagtcgaa
gaccatgtggcgtttttaataacagtcccaactgccctggcgatcttctttgcgatattc
atcctcgtgtgcatcgagtccgtgtttaagaagctgctacgccttttctctttggtgata
tggatgtgtctggtggccatggggtacttgttcatgtgctttggaggcaccgtctccccc
tgggaccaggtgtccttcttcctcttcattatcttcgtggtatacaccatgctccccttc
aacatgcgagacgccatcatcgccagcgtgctcacggcctcctcccacaccgtcgtgctg
agcatctgcctgtctgcaacgcccggggccaaggagcacctggtctggcagatcctggcc
aacgtgatcattttcatctgtgggaacctggcgggagcgtaccacaagcacctcatggaa
cttgctctgcagcagacgtaccaggacacgtgcaattgcatcaagtcccggatcaagctg
gaatttgaaaagcgtcagcaggagcgtctcctgctgtctctgttgccggctcacatagcc
atggagatgaaagctgagatcatccagaggctgcagggccccaaagccggccaaatggaa
aacacaaacaactttcacaacctgtatgtcaagcgacataccaatgtgagtatcctgtac
gcagacatcgttggcttcacccggttggccagtgactgctcgccaggagaactggtccac
atgctgaacgagctctttggaaagttcgatcaaattgcaaaggagaatgagtgcatgaga
ataaaaattttgggagactgctactactgcgtgtccggactccccatatctctcccgaac
catgccaagaattgtgtgaaaatgggactggatatgtgtgaagccataaagaaagtgagg
gacgccaccggcgtggatatcaacatgcgcgtcggagtgcattctgggaacgtcctctgc
ggcgtgatcggtctgcagaagtggcagtatgacgtgtggtcacatgacgttaccttagcc
aatcacatggaagccggaggggttcctggacgtgttcacatttcttctgtcaccttggaa
cacttgaatggcgcttataaagtggaggaaggagatggtgacatcagagacccatattta
aaacagcacctggtgaaaacctactttgtaatcaaccccaagggggaacgacggagtcct
cacctcttcagacctcgccacaccctcgatggagccaagatgagggcttccgtccgcatg
acccggtacctggagtcctggggagcagccaagccctttgcacacctgcatcaccgagat
agcatgaccacggagaacggcaagatcagcaccacggatgtgccaatgggtcagcataat
tttcaaaaccgtaccttaagaaccaagtcgcaaaagaagagatttgaggaagagttaaat
gaaaggatgattcaagcaattgatggaattaatgcacaaaagcagtggctcaagtctgaa
gacattcagagaatctcgctcctgttctacaataaaatactagaaaaagaataccgagcc
accgcactgccagcgttcaagtattacgtgacctgcgcgtgtctcatattgttctgcatt
tttgtcgtgcagattctggtattacccaagacgtccattcttgggatctcctttggagcc
gcgtttctcttgcttgcctgtatccttttcgtctgctttgctggacagcttttgcaatgc
agcaagaaggcctccgcctctctcctgtggctgctgaagtcgtccagcatcatcgcggac
cggccctggccgcgggtctccctcacggtcctcaccaccgccatcatcctgaccatggcc
gtgttcaacatgtttttcctgagcgacccagaggaagccatgcctccgcctgccaacaca
tcaaacacgagtctttctgccttaaacaatcaggcagtgattctgcgagcacagaatttg
tttttcctcccgtactttatctacagctgcattctgggactgatttcctgctcggttttc
ctgcgggtgaattatgagttgaaaatgctgatcatgatggcggcgttgataggctacaac
accatccttctccacactcacgcccacgtcctggacgactacagccaggtcttatttgag
agaccaggcatttggaaagatctgaagaccatgggctcagtgtctctctttatatttttc
atcacactgcttgttctgggtagacagaatgaatattactgtaggttagacttcttgtgg
aagaacaagttcaaaaaagagcgggaggagatagaaaccatggagaacttgaaccgcgtg
ctgctggagaacgtgctgcccgcgcacgtggccgaacatttcctggcccggagcctgaag
aacgaggagttgtaccaccagtcctacgactgtgtctgtgtcatgtttgcttccattccg
gatttcaaggaattctacacagaatcggatgtgaacaaggagggcttggaatgccttcgg
ctcctgaacgagatcatcgccgactttgatgatctgctgtccaagccgaaattcagtgga
gttgaaaagatcaagaccatcggcagcacgtatatggccgcgaccggtctgagcgccgtg
cccagccaggagcatacccaggagcccgagaggcagtacatgcatatcggcaccatggtg
gagtttgcctttgccctggtggggaagctggacgctatcaacaaacactccttcaacgac
ttcaagctgcgagtgggtattaaccatgggcctgtaatagccggtgtgattggagctcag
aagccacaatacgatatctggggcaacaccgtgaatgtggccagcaggatggacagcacc
ggcgtgctggacaaaatacaggtcactgaggagacaagcctcatcctccagaccctgggg
tacacgtgcacgtgtcgaggaataatcaacgtgaaaggcaagggggagctgaagacgtac
tttgtaaacacggaaatgtcaaggtccctttcccagagcaacgtggcatcctga
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integrated database retrieval system
