KEGG   Perognathus longimembris pacificus (Pacific pocket mouse): 125355478
Entry
125355478         CDS       T08928                                 
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
plop  Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00140  Steroid hormone biosynthesis
plop01100  Metabolic pathways
plop04913  Ovarian steroidogenesis
plop04925  Aldosterone synthesis and secretion
plop04927  Cortisol synthesis and secretion
plop04934  Cushing syndrome
Module
plop_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
plop_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
plop_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
plop_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:plop00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    125355478
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    125355478
   04925 Aldosterone synthesis and secretion
    125355478
   04927 Cortisol synthesis and secretion
    125355478
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    125355478
Enzymes [BR:plop01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     125355478
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     125355478
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 GDP_Man_Dehyd Polysacc_synt_2 NAD_binding_10 RmlD_sub_bind NmrA KR Ilm1 Ldh_1_N
Other DBs
NCBI-GeneID: 125355478
NCBI-ProteinID: XP_048207832
LinkDB
Position
7:72188720..72195350
AA seq 373 aa
MAAWSCLVTGAGGFLGQKIISFLMEEKELQEIRAMDKNITPDIREEFSKLQTKAKMTVLE
GDILDAQCLRRACQGVSIVIHTAALIDVTGVNLRETIMDINFKGTQLLLEACVQASVPIF
IHTSSVEVAGPNSYKEIIQNGQEEEPLECRWTEPYPYSKKLAEKAVLAANGCTLKDGGTL
HTCALRPMYIYGEGSKLISPIVKRALTTNGVLEKTGPFSLVNPVYVGNVAWAHILACRGL
RDPKKAPSIQGQFYYISDDTPPQSYDDLNDTLCKEWGLRRDSRPSPPLFLMYWLAFLLEA
VSFLLSPIYTYRPPFTRHLLVLSNSAYTYSYKKAQRHLGYEPRFSWEEAKQKTTEWVGSL
VKQHKGTLKSKAQ
NT seq 1122 nt   +upstreamnt  +downstreamnt
atggctgcttggagctgcctggtgacaggggctggaggatttctgggccaaaagatcatt
agcttcttgatggaggaaaaggagctgcaagagatcagggcaatggacaaaaacattact
ccagacatcagagaagaattttcaaagctacagaccaaggccaagatgacagtgctggaa
ggagatattctggatgcccagtgtctgaggagggcctgccagggagtctctattgtcatc
catactgctgctctgattgatgtcactggcgtcaatctcagagagaccatcatggacatc
aacttcaaaggtacccagctcctattggaagcctgtgtccaagcaagtgtaccaatcttc
atccataccagctcagtggaagtggcaggacccaactcctacaaggagatcattcagaat
ggccaggaggaagagcctctcgaatgcaggtggactgaaccatacccatacagcaaaaag
ttggctgagaaggctgtgttggcagccaatgggtgcactcttaaagatggtggtaccttg
catacttgtgccttaaggcctatgtacatctatggggaaggaagcaaactaatttccccc
attgtgaagagagccctcacaaccaacggtgtactggaaaaaacaggcccattttctctg
gtcaacccagtctatgtgggcaatgtggcctgggcccacattctggcctgcagaggcctg
agggatcccaagaaggcaccaagcatccaggggcagttctactacatatcagatgacaca
cctccccaaagctatgatgacttaaatgataccctgtgcaaagaatggggcctccgccgc
gactccaggcccagccctcctctcttcctgatgtactggcttgccttcctgctggaagca
gtgagcttcctgctgagccccatctacacataccgacccccctttacccgacatttactg
gtactctcaaacagcgcgtacacctactcctacaagaaagcacagaggcatcttgggtat
gagccccgcttctcctgggaggaagccaagcagaaaaccacagaatgggttggttcactt
gtgaagcagcacaaggggacactgaagtcaaaagctcagtga

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