Perognathus longimembris pacificus (Pacific pocket mouse): 125359897
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Entry
125359897 CDS
T08928
Symbol
Hsd11b1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00140
Steroid hormone biosynthesis
plop00980
Metabolism of xenobiotics by cytochrome P450
plop01100
Metabolic pathways
plop05204
Chemical carcinogenesis - DNA adducts
Module
plop_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
125359897 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
125359897 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
125359897 (Hsd11b1)
Enzymes [BR:
plop01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
125359897 (Hsd11b1)
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
2-Hacid_dh_C
Pyr_redox_2
Shikimate_DH
Pyr_redox_3
Methyltransf_25
Pyr_redox
Motif
Other DBs
NCBI-GeneID:
125359897
NCBI-ProteinID:
XP_048213715
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All DBs
Position
11:complement(54578072..54631586)
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AA seq
292 aa
AA seq
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MAFVNKYVLSILVLFLAFYYYSEKEEFRPEMLQGKKVIVTGASKGIGREMAYHLARMGAH
VVVTARSEETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAKAGKLMGGLDMLILNH
ITSSTMTLFHDDISHVRKSMEVNFFSYVTLTVAALPMLKQSNGSIAVVSSMAGKISHPLI
APYSASKFALDGFFSSIRNEHSLMKVNVSITLCILGLIDTDTAMKAVSGIVNFKAAPKEE
CALEIIKGTALRQDEVYYHNSPWTMFLLGNPGRRILEFWTMKQYNMEKFIKN
NT seq
879 nt
NT seq
+upstream
nt +downstream
nt
atggcttttgtgaacaaatatgtgctctccatcctggtgctcttcttggccttctactac
tactctgaaaaggaagaattcagaccagagatgctccaaggaaagaaagtgattgtgaca
ggggccagcaaagggattggaagagaaatggcttatcatctagcaagaatgggggcccat
gtggtggtgacagcaaggtcagaagaaactctacaaaaggtggtatcccactgcctggaa
cttggcgcagcctcagcacactacattgctggcaccatggaagacatgacgtttgcagaa
caatttgttgccaaagcaggaaagctcatggggggactagacatgctcatcctcaaccac
atcaccagctcgacaatgactctttttcatgacgatatctcccatgtgcggaaaagcatg
gaggtcaactttttcagttatgtgaccctcaccgtagccgccttgcccatgctgaagcag
agcaatggaagcattgctgtcgtctcttcaatggctgggaagatctctcatcccctgatt
gctccctactctgcaagcaagtttgctctggatggattcttctcttccattaggaatgaa
cactcacttatgaaggtcaatgtgtcaatcactctctgtatccttggcctcatagacaca
gacacagccatgaaagcagtttctgggatagtaaatttcaaagcagctccaaaggaagag
tgtgccctggagatcatcaaagggacagctctacgtcaagatgaagtgtactaccacaac
tccccctggaccatgttccttcttggcaatccagggaggaggatcttggagttttggaca
atgaaacaatataatatggagaagtttataaaaaactag
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