KEGG   Perognathus longimembris pacificus (Pacific pocket mouse): 125362735
Entry
125362735         CDS       T08928                                 
Symbol
Pak1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
plop  Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop04010  MAPK signaling pathway
plop04012  ErbB signaling pathway
plop04014  Ras signaling pathway
plop04024  cAMP signaling pathway
plop04062  Chemokine signaling pathway
plop04360  Axon guidance
plop04392  Hippo signaling pathway - multiple species
plop04510  Focal adhesion
plop04625  C-type lectin receptor signaling pathway
plop04650  Natural killer cell mediated cytotoxicity
plop04660  T cell receptor signaling pathway
plop04666  Fc gamma R-mediated phagocytosis
plop04810  Regulation of actin cytoskeleton
plop05132  Salmonella infection
plop05170  Human immunodeficiency virus 1 infection
plop05205  Proteoglycans in cancer
plop05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:plop00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125362735 (Pak1)
   04012 ErbB signaling pathway
    125362735 (Pak1)
   04014 Ras signaling pathway
    125362735 (Pak1)
   04392 Hippo signaling pathway - multiple species
    125362735 (Pak1)
   04024 cAMP signaling pathway
    125362735 (Pak1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125362735 (Pak1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125362735 (Pak1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    125362735 (Pak1)
   04650 Natural killer cell mediated cytotoxicity
    125362735 (Pak1)
   04660 T cell receptor signaling pathway
    125362735 (Pak1)
   04666 Fc gamma R-mediated phagocytosis
    125362735 (Pak1)
   04062 Chemokine signaling pathway
    125362735 (Pak1)
  09158 Development and regeneration
   04360 Axon guidance
    125362735 (Pak1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    125362735 (Pak1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    125362735 (Pak1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    125362735 (Pak1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125362735 (Pak1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:plop01001]
    125362735 (Pak1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:plop04131]
    125362735 (Pak1)
   03036 Chromosome and associated proteins [BR:plop03036]
    125362735 (Pak1)
Enzymes [BR:plop01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     125362735 (Pak1)
Protein kinases [BR:plop01001]
 Serine/threonine kinases: STE group
  STE20 family
   125362735 (Pak1)
Membrane trafficking [BR:plop04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    125362735 (Pak1)
 Endocytosis
  Macropinocytosis
   Kinases
    125362735 (Pak1)
Chromosome and associated proteins [BR:plop03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     125362735 (Pak1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 125362735
NCBI-ProteinID: XP_048217602
LinkDB
Position
13:complement(1970904..2081189)
AA seq 544 aa
MSSNGLDTQDKPPAPPMRNTSTMIGAGGKDPATLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTTNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATSPPVIAPRPEHTKSVYTRSVIEPLPITPTRDVATSPISPTENNTTPPDALTRNIEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNSH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaagtaacggcctagacactcaggacaagcccccagcccctcccatgagaaacacc
agcactatgattggagctggcggcaaagaccctgcaaccctcaaccatggctccaaacct
ctgcctccaaaccccgaggagaagaaaaagaaggatcgattttacagatccatcttacct
ggagataaaacaaataagaagaaggagaaggagcggccagagatttctcttccttcggat
tttgagcacacaattcatgtcggttttgatgctgtcacaggggagtttacagggatgcca
gagcaatgggcccgtttgcttcaaacatcaaatatcactaaatcagagcagaagaaaaac
ccacaggctgttttggatgtgttagagttttacaattctaagaagaccaccaacagtcag
aagtacatgagctttacagataagtcagctgaagattataattcttctaacactttgaat
gtgaagaccgtgtctgagacccctgcggtgccaccggtttcggaggatgaagatgatgat
gatgatgccacctctcctccagtgattgctccacgcccagagcacacaaagtctgtatat
acacgctctgtgattgaaccacttcctatcactccaactcgggatgtggctacatctccc
atttcacctactgagaataacaccactccaccagatgcattgacccggaatattgagaag
cagaagaagaaacccaaaatgtctgatgaggagatcttagagaaattacggagcatagtg
agcgtgggcgatcctaagaagaagtacacacggtttgagaagattggacaaggtgcttcg
gggactgtgtacactgcaatggatgtggccacaggacaggaggtagccattaagcagatg
aatcttcagcagcagccgaagaaagagctgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactacttggacagctaccttgtaggagatgagctatgg
gttgtcatggagtacctggctggaggctccttgacagatgtggtgacagagacctgtatg
gatgagggccagatcgctgcggtgtgccgtgagtgtctgcaggccctagagtttctacat
tcgaaccaagtcattcacagagacatcaagagtgacaatattctgttgggaatggatggc
tctgtcaagttaactgattttggattctgtgcacagataaccccagaacaaagcaaaagg
agcaccatggtggggactccatattggatggcacctgaggttgtaacgcggaaggcctat
ggacccaaagttgacatctggtccctgggcatcatggctattgagatgattgaaggggag
cccccatacctcaatgaaaaccctctgagagccttgtacctcattgccaccaatgggacc
ccagaacttcagaacccagagaagctgtctgctatcttccgggactttttaaatcgctgt
ctggagatggatgtggaaaagagaggctcagctaaagagctcctgcagcatcaattcctc
aagattgccaagcccctctccagcctcactcccttgattgctgcggcaaaggaggcaacc
aagaacagtcactaa

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