KEGG   Parus major (Great Tit): 107201331
Entry
107201331         CDS       T04864                                 
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pmaj  Parus major (Great Tit)
Pathway
pmaj00562  Inositol phosphate metabolism
pmaj01100  Metabolic pathways
pmaj04020  Calcium signaling pathway
pmaj04070  Phosphatidylinositol signaling system
pmaj04081  Hormone signaling
pmaj04082  Neuroactive ligand signaling
pmaj04261  Adrenergic signaling in cardiomyocytes
pmaj04270  Vascular smooth muscle contraction
pmaj04310  Wnt signaling pathway
pmaj04371  Apelin signaling pathway
pmaj04540  Gap junction
pmaj04621  NOD-like receptor signaling pathway
pmaj04912  GnRH signaling pathway
pmaj04916  Melanogenesis
Module
pmaj_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pmaj00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    107201331 (PLCB4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    107201331 (PLCB4)
   04371 Apelin signaling pathway
    107201331 (PLCB4)
   04020 Calcium signaling pathway
    107201331 (PLCB4)
   04070 Phosphatidylinositol signaling system
    107201331 (PLCB4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    107201331 (PLCB4)
   04081 Hormone signaling
    107201331 (PLCB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107201331 (PLCB4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    107201331 (PLCB4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    107201331 (PLCB4)
   04916 Melanogenesis
    107201331 (PLCB4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107201331 (PLCB4)
   04270 Vascular smooth muscle contraction
    107201331 (PLCB4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pmaj04131]
    107201331 (PLCB4)
Enzymes [BR:pmaj01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     107201331 (PLCB4)
Membrane trafficking [BR:pmaj04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    107201331 (PLCB4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    107201331 (PLCB4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 107201331
NCBI-ProteinID: XP_015476014
Ensembl: ENSPMJG00000000495
LinkDB
Position
3:4818083..5003404
AA seq 1206 aa
MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESNCLFQVDEFGFFLSWKSEGKEGQVL
ECSLINSVRFGAVPKDPKILTALEAVGKSENELEGRIVCVCSGTDLVNISFTFMVAENTE
IAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKRKGVISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQPLETHPLEQGKALPSPNDLKRKILIKNKRLKPEVEKKQLDALKKM
MEAGETTAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVE
DSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNI
HHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNPKANVTPQ
SSSELRPSTTAGFGSGTDTKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELNALKKKHAK
EHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCVELKKETEIKIQTLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQAGNSGL
KPQQAN
NT seq 3621 nt   +upstreamnt  +downstreamnt
atggcaaaaccttatgaatttaactggcagaagccagttccctcttttatgcaagatgga
gctgtgtttgatagatatgaggaggaatcttttgtatttgaaagcaactgtctgttccaa
gtggatgaatttggtttttttctgagctggaaaagtgaaggaaaggagggacaggtatta
gaatgctccctgatcaacagtgttcgctttggagctgtaccaaaggatcccaaaatacta
actgcacttgaggctgttggaaaatcagaaaatgagttggaaggacggatagtgtgtgtt
tgcagtggcacagatctggtgaacatcagcttcactttcatggtagcagaaaacacagaa
atagccaagcaatgggtagaagggcttggatccatcatacataactttagagctaacaat
gtcagtccaatgacgtgtctcaagaaacactggatgaagctggccttcctaacaaacaca
aatgggaaaattccagttcggagcataaccagaacctttgcatcaggtaaaacagaaaaa
gtgatctttcaggcacttaaggaattaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcttttacttatgagaaattttatgagcttacccaaaagatatgtccccgaact
gacatagaggatctctttaagaagatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctcaatgaaattttattt
cccttttatgacacaaaaagagcaatgcagataattgagacatatgagccagacgaagac
ttgaagaggaaaggtgtcatatccagtgatgggttttgcagatacttgatgtcagatgaa
aatgccccagttttcttggaccgtttggaattatatcaagaaatggaccatcctctggct
cattatttcatcagctcctctcacaatacgtatttaacaggcaggcagtttggtggcaag
tcttcagtggagatgtacagacaagtgcttttggctggatgcaggtgtgtcgagctggac
tgttgggatggcaaaggtgaagaccaagaaccaataataacccatggaaaagcaatgtgc
acagacattcttttcaaggatgtaattcaagccattaaggaaacagcatttgttacatca
gagtatcctgtcattctttcatttgaaaatcactgcagcaaatatcaacagtacaagatg
tcaaaatactgtgaagatctttttggagatctcctgttgaagcagcctctagaaacacat
ccacttgaacaaggtaaagctttaccatctcctaatgacctcaaaagaaagattctcata
aagaataaaagactgaaacctgaagtagaaaagaaacagcttgatgctctgaaaaagatg
atggaggctggggaaactactgcacctgtaaatatcctggaggatgataacgaagaggaa
atagaaagtgctgaccaggaagaagaagctcatcctgagtacaaatttggaagtgacctt
actgtagatgattatagtcaaaaagaagctgttgccatcagcgtcaaaaaggctgttgaa
gattctgagcaagaaaacaataaaaagggtttagtaactgtggaagatgaacaagcgtgg
atggcatcttacaaatatgtaggtgccacaaccaatatacatccatatttatcaacaatg
gtcaactatgctcaacctgtaaaatttcaaggtttcgatgtagcagaagaacgtaatatt
caccataacatgtcctctttcaatgaatcagtcggactagggtatttgaagactcatgcc
attgagtttgtgaattataataaacgacaaatgagtcggatatacccaaagggaggccgt
gtggattccagtaattacatgcctcaaattttctggaacgctggctgccagatggtctca
ctgaactatcagaccccagatttggcaatgcagttgaatcaaggaaaatttgagtacaat
ggatcgtgcgggtatctactaaagccagatttcatgagaagaccagacaggacgtttgac
cctttctctgaaactcctgtagatggtgttattgctgcaacatgttctgtacaggtgata
tctggccagttcttgtcagacaagaagattgggacctatgtggaggtggatatgtacggg
ctgcccacagacacgatacgcaaggagttccgcacgcgcatggtgatgaacaacggcctg
aaccctgtttacaacgaggagtcctttgtctttaggaaggttatcctccctgatcttgct
gtcctgagaatagcagtgtatgatgacaataataaactgattggtcagaggatcctgcct
ctggatgggctgcaagcaggttacagacacatttcccttcggaatgagggcaacaaacca
ctctctcttccgacggttttctgcaacattgtgcttaaaacatacgtgcctgatggtttt
ggagatattgtggatgctttatcagatccaaagaaatttttgtctatcacagaaaaaaga
gcagaccaaatgagagctatgggtattgaaactagtgatatagctgatgtaccaaatgac
acttcaaagaatgacagaaaaggaaaagccaataatcccaaagccaatgtaacacctcag
agcagctctgagcttcggccaagcaccactgcaggctttgggtctggcaccgacactaag
aaaggtatagaccttattcctcaagtgaagatagaagatttaaagcaaatgaaggcttat
ataaagcatttaaagaaacagcagaaagagctgaatgccttaaagaagaaacatgctaag
gagcacagtgccatgcagaagttgcactgcacacaaattgacaaaatagtggcccaatat
gacaaagaaaaggtatcatatgagaaaatgctagagaaggcaatcaagaagaagggagga
agtaattgtgttgaattgaagaaagaaacggaaattaaaattcagacactaacatcagat
cacaaatctaaggtcaaagagatcgtggctcagcacaccaaggagtggtccgagatgatc
aacacgcacagcgccgaggagcaagaaatccgtgacttgcacttgaaccaacagtgtgaa
ctactgaagaaactgctcattaatgctcacgaacaacaaacccagcagctgaaattttcc
catgacagggaaagcaaggagatgcgtgccaaccaggctaaaatatccatggagaacagc
aaagccattagccaagacaaatctatcaaaaacaaagctgaaagagagaggcgagtcaga
gaactgaacagcagcaacacgaaaaagttcctggaagagagaaaaaggctggcaatgaag
cagtcaaaggaaatggatcagttgaaaaaagttcaacttgagcacttagaagtcttggag
aagcagaacgagcagcttttgaaatcctgtcatgcagtgtctcaaacacaaggcaaagga
gatgcagcagatggtgaagctggaagcagagatggatcgcaggccggcaacagtggttta
aagcctcaacaagcaaattga

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