Parus major (Great Tit): 107201413 Help Entry 107201413         CDS       T04864                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism pmaj  Parus major (Great Tit) Pathway pmaj04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pmaj00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     107201413 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pmaj03036]     107201413 (SYNE1) Chromosome and associated proteins [BR:pmaj03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     107201413 (SYNE1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin SYNE1 Spectrin_SYNE1 KASH SR_desmoplakin_3 SYNE3 DUF6317 Motif Other DBs NCBI-GeneID:  107201413 NCBI-ProteinID:  XP_033368637 Ensembl:  ENSPMJG00000009003 LinkDB All DBs Position 3:55234317..55535470 Genome browser AA seq 5805 aa AA seqDB search MTDEIKTQLNDLCKFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTALR DFQQWLVNARVTTAKCFDVPQNISEASASLQKIQEFLSESENGQQKLNLVASKGELLCSV LPKEKAKVIQDKSASAKEDWKNFITTLHQKKSALENLTIQMKDFEATAEPLQEWLTTTEK IVQGSSSRLYDLPSKRREQQKLQSVLEEISCHEHQLNRLKEKAQQLWEEQAVSKSFMRRV SQLSSQYLTLSNLTKEKVSRMDRIVAEHQQFLQSVKDLQDWVADAVHMLDSYSHPTVDKS VLDNRMLKLEGLLAVKQEKEVQMKIVLTRGESVLQNTSLEGVPVVEGQLQNLKDSWASLL SACIQCKSQLEGALSKWTSYQEDVNQFSRWMEKVEASINASERQHAELREKTAALSKAKL LNEEVLSHNSLLETIEVKGKGMAEHYIAQLELQDLQERYKFLKEKTKEAVTKAEGLLTLH QEYQRNLKAFEVWLEKEQEKLDCLSHLDGDAQEQEATLRDLQELQVHCAEGQALLNAAVH AREEVIPWGIPQIEDRTLESLRQDWQVYQHRLSEARSQLNATVSKLRLMEKKFQKVNNWL TNLEEKAAIRTGRRSGRATKEMQLQQMKKWHEDITIYKDDVEEVGVLAQQILEENLTASR MGSQATQLTSRYQTLLLHVLEQVKFLEEEIRCLEESELSFSAYTNWYGATNKNFKNAITK FDVVDKTVMEKKVQKLEVLLSDMDIGHSLLKSAREKGERAIKYMEENKVDQLRKEIGDHV EQLEELAGSIRKEHMTSEKCLQLVKEFSDKYKAQTQWVMEYQAILHAPVEPKSELYEKKA QLSKYKSVQQTVLSHEPSIKSVIEKGEALCDLVNDVTLKNSIQDLQSSYQELCSKTKAYV ETLEVRVKEHEDYNSDLQEGEKWLLHMSSRLASPDLMESNNLEIITQQLANHKAIMEEIA GFEDRLNNLKSKGDYLISQCSEHLQAKFKQNIQSHLQGTRDSYSAICSTAQRVYQTLEHE LQKHVNHQDTLQQCQTWLSTVQSELKPPTWTPFSLADAVKQVKHFRALQEQANTYLDLLC SMCDLSDATVKSTAADIQQTKQTIEQQIMHSQYLSQGWEEIKQLKAELWIYFQDADQQLQ NLKRRRAELELNIAQNMVLQVKEFSQKLQSKQSDLTSVTEKMNKLTQGQESPEHKEIGEL SNQWLDLCLQTHSLLMQREEDLQRTRDYHDRMNVVEVFLEKLTKEWDNLARSDAESTNVH LEALQKLAVALQERRFALEDLKDQKQNMIEHLNLDDKELVKEQFSHFEQRWTQLEDLVKR KIQVSVSTLEELSLVHSKFQELMEWAEEQQPSVSEALKQSPPPDMAQTLLMDHLTICSEL EAKQLLLKMLVKDADRVMTNLGLNERQELQKTVSDAQHHVACLSDLVGQRRKHLNKALSE KTQFLMAVFEATNQIHQHEKKVMFPEHICLLPEDVNKQIRTCKNTQANLKACQNEVTGLW AQGRDLMKEATNQEKREVLGKLQELQNVYDTVLQKCNQRLLELEKNIVSRKYFKEDLDKV CHWLKQADIVTFPEVNVMNSNTELHSQLAKYQQILEQSPEYENLLLTLQRDGQEVLPSLN EVDHSYLDEKLNSLPQQFNIVTALAKEKLYKVQEAIYARKEYASLIELTSKALTELEDQF INMDKAPAAVSAKEAVSLQQAYRDLLGEAMSLAAAVDELNQKKEAFRSTGQPWQPDEMLK LATLYHKLKRQIEQKINLLEDTIEACQEHEKMCMQFEAQLEAVKKEQVKVNEETLPIEEK LKIYHSLVGSLQDSGSLLKRITEHLETLSPQVDPSAYETTNHQVQAWQEKLKSLHSAIVD TVMECENRLVQSIDFKTEICRSLDWLRWVKTELNGTISLDLKLQSIQEEIRKVQIHQEEV QSSLRIMNALSNKEKERYMKAKELIPADLENTLAELAELDGEVQEAIHVRQASLNKAYGL CQRYYQVMQIANDWLEDAQEFLQLARSGLDVENSEENLRNHVEFFITESQFNDNLKVLQG LVSEIEPFLQATASEQLVQNVAALEEKAKVTEQEAKTQQEQLQRCASEWLEYQTSRQKVI EVMNDAEKKLSEFSVAKAASSHEAEEKLLTHKTLVSVVNSFHEKITALEEKALQLEKISN DASKASISRSMTTVWQRWTRLRNVAQEQEKILEDALQEWKGFNDKIQKATIAIDQLQGRL PESSVEKASKTELLELLDYHGSFLLEVDHQLSSLGLLKQHAVSMLQDVEVKTPSQKELPV MQEIKAMQDRCHNMQQKVKKGMKMVKQELKEREEVEAEINIVKSWIQETKEYLLSPDAEV DIQLQELQSLFGEVATHRQAVEKLAEQQQNKYLGLYTILPSELSLHLAEVGLALVTVQDQ IQTKERETQQIKTLNQEFDQKIQGIANELNTILSKLKKKTNDIAQAKLEQKILGDELDSC NIKLLELDASVQDFAEQNVPLAKQLANRIGKLSALHQQTIRQAEYRAAKLSQAASHLEEY NEMLEFILRWIEKANILVHGSITWNSSSQLRDQFKAYQSILDESGEIHSDLEAMSERIDY LASVYSTEGMSQQVLELGRRTEELQQVIKVQLPNLQDAAKDMKKFEIELRALQGALEQAQ ATLTSPELGHLSLKEQLSHRQHLLSEMESLKPKVQAVQECQSALRIPEEVVTSLPMCHSA LRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQDKPIATSNIQ ELQVQISRNEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLSEGMEELD SDLLPAHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASV NQDIAYYQALSAEQLQTEAAKIQPSTSATQEFYEPGLESSASAKLDDLQRSWETLKNVIS EKQRTLYEALERQQKYQDTLQSISTKMETTEIKLSESLEPAKSPESQMAEHQALMDEILM LQEEISELQTSLAQELVSEPLDAEGADQMALQSTLTVLAERMATIRMKASGKRQLLEEKL NEQLEEQRQEQALQRYRCEADELDHWLLSTRATLDSALLPAEEPMDMEAQLVDCQNMLVE IEQKVVALSELSVHNENLLMEGKAHTKDEAEQLAVKLRTLKGSLLELQRVLHDKQINIRQ GSLQEKEESDLDFVSSQSPSVQEWLVQARTTRSQQQQSTLQQQKELEQELEEQKNLLRSV ACRGGEILTQQGSTEGLSISEKPDVLSEELTLEVEKPSSEEQMKRKWESLNQEFSTKQRL LQKALEKEQLQLYSRPNRLIPGMPLYKEETQDEDKSLVSPVLVELNQAFEDVSSEAGRVE ETLQLEQKLYDGVTATSVWLDGVEEQVFVATALLPEEETETYLCKQESLAKEIKDITEEV DKNKNLFAQIFPDSSDKRVIIEDTLDCLLRRLTLLESVVNQRCHQMKGRLQQIITFKNDL KLMFTSVADNKYLVLQKLAEAADRPETEQMQVILHAEEGLKELDAGISDLKKRIDKLQID QPSIQELSKIQDKYDELLMIIGSRRSDLNQNMALKRQYERALQDLADLVETGQEKMAGDQ KMIVSSKEEVQSLLEKHKEYFQGLESHMILTETLFRKMSSLALLKETQSHSEIMTRASAV LKLAHKRGVELEYILETWMHLDEDYQELTRQLESVEGNIPTVGLVEETEDRLTDRITLFQ HLRSNLTEYQPKLYQVLDDGKRLLFSVSCSELEGQLNQLGERWLSNTSKVTKELHRLETI LKHWTRYQSESNELTQWLQSAKERLEFWSQQSLTVPQELETVRDHLNSFLEFSKEVDAKS SQKSSVLSTGNQLLRLKKVDTAALRAGLSHIETQWTELLTQIPAVQEKLHQLQMDKIPSR HAITEVMSWISLMENVIQQDEENIKNVVGQKAIQGYVQKYKGFKIDLNCKQLTVDFVNQS VLQISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLITEKIQLLEGLQESWTEYENNVQC LKIWFETQEKKLKQQQKIGDQASVQNALKDCQELEESIRAKEKEVENVEQSGLSLIQNKK EEVSSAVMNTLQEINHSWANLDHMVSQLKILLQSVLDQWSIYKVAYEELNSYLTEARYSL SRFYLLTGSLEAVKVQVDKLQSLQDELEKQENSLQKFGSVTNELLKECHPPVTETLTNTL KEVNMRWNNLLQEIAERLRASKALLQLWQRYKDCYQQCSSTVHQREDQTNELLKTATSKD IADDEVTTWIRDCNDVLADLKTAQESLVVLQELGEELKSQVEASAAAAIQSDHLSLNQSL TTLEQTLCKQQAVLQAGILDYQTFSKSLEVLETWITEAEETLKEQDPSHSSDVSAIQSRM EQLKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISPQTTERFSKLQS FLLQQQTFLEKCGTWMDLLVQTEQKLAVEVSGNYQRLLEQQREHELFQAEMFSRQQILHS IISDGQHLLEQGQVDDRDEFNLNLTLLSNQWQGVIRRAQQMRGIIDSRIHQWQRYREMAE KLRKWLLEMSCQPVTELGTVPIPLQQARVLLDEVQLKEKVLLRQQGSYILTVEAGKQLLL SADSGAEAALQAELTEIQERWKIVSTQLEQQKKQLALLLKDWEKCEKGIGDSLEKLRSFK KKLSQPLPDHHDELHAEQIRCKELENAVEGWTDDLTHLSLLKETLSVYISADDISILSER IELLHRQWEELCHQVSLRQQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEE MIEKLKKDYQEEIAVAQKNKIQLQQMGERLAKASHESKASEIEYKLGKINDRWQHLLDLI AARVKKLKETLIAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEIQRKLNEQQELQ RDIEKHSTGVASVLNLCEVLLHDCDACATEAECDSIQQATRNLDRRWRNICAMSMERRLK IEETWRLWQKFLDDYSRFEEWLKASERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESL TQLELINKQYRRLARENRTDSNGSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEF ETARDNILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNSKIEQIIVQGEQL IEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLSDREVDLDESA DLSDIRWHDKSADSVLSPHPSSNLSLPLSQPLRSERSGRDTPASVDSIPLEWDHDYDLSR DLETAVSRALHSEEDGGQEKDFYLRGAAGIADVEIPETLEAYVTLTENALKNISGEPGAL EAHIRQLDKALDTSRFQIQQTENIIRSKTPTGPELDSTYRGYMKLLGECSGSIDSVRRLG YKLKEEEEKFSGLINMNSTETQTAGVIERWELIQAQALSKELRMKQNLQQWQQFNSDLNS IWAWLGETEEELEKLHRLDLSTDIQTIELRIKKLKELQKAIDNRKAIILSINLCSSEFTQ SDSEESKKLQERLSQMNVRWEHVCSMIEDWRSSLQDALVQCQDFHELCHGLLLWLENIDR RKNEIVPINPNLDSEILQDHHRLLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDCLEA KEKVHVIGNRLKLLLKEVTRHIKDLEKILDISSSQLELSSWSSDELDTSGSVSPVSGRST PSRQRTPRGKCSLSQPGPSVSSPHSRSKRGGSGSSPSEAGPVWRCPSFFLRVLRAALPLQ LLLLLLIGLACLVPMTEEDYSCAMANNFARSFHPMLKYMNGPPPL NT seq 17418 nt NT seq  +upstreamnt  +downstreamnt atgacagatgagatcaaaacccagttgaatgatctttgtaaattttccagggatttaagt actcattcttcaaaagtttcagggttgattaaggagtataacagcctctgcctgcaagct tcaaagggatgtcagagcaaagagcagatcttgcagcaaaggtttcggacggctctcagg gattttcagcagtggctggtcaacgcaagagtcaccactgccaaatgcttcgacgtgcct caaaacatcagtgaagcttcagcaagtctgcagaaaatacaggaattcctatcagaaagt gaaaatgggcaacaaaaattaaacctggtggcatccaaaggagaactgctgtgctctgtt ttaccaaaggaaaaggctaaagttatccaggacaaatctgcttctgctaaagaagattgg aaaaattttatcaccacgctccaccagaagaaatctgcattggagaatttaacaatccag atgaaggactttgaagcaactgctgagcctctgcaggagtggctgaccacaactgagaag atagtacaaggaagtagcagtcggctctatgatcttccttccaagagaagagaacagcaa aagctgcagtctgtccttgaggaaataagctgccacgagcatcagctcaacaggctaaaa gagaaagctcagcagctgtgggaagaacaagctgtcagcaaaagctttatgcgcagagtg tctcagttgtcttctcagtatcttactctaagcaatctgacaaaggagaaagtttccaga atggataggattgtagcagagcaccagcagttcttacagagtgtcaaggacctccaggac tgggttgctgatgcagttcacatgttggattcttactctcatcctactgtggacaagagt gttctggacaaccggatgttaaaactagagggcctgctagcagtgaaacaagaaaaggaa gtccaaatgaaaattgttctgacaagaggagaatctgttctgcaaaatacttctctggag ggagtaccagtggttgaaggccaattgcaaaatctgaaggacagctgggcttctcttctg tctgcttgtatccagtgcaagagtcaactggaaggagctctctccaaatggacaagttac caggaagacgttaatcagttttccagatggatggaaaaagtagaagcaagtattaatgct tctgaaaggcaacatgctgaactgagggaaaaaacagctgccctcagcaaagcaaagcta ctgaatgaagaggtgttgagtcataacagcctgttggagactattgaagtgaaaggaaag gggatggctgagcattacattgctcagcttgagctgcaagaccttcaggagagatataag ttcctcaaagaaaaaacaaaggaggctgtaacaaaagctgaaggactgcttaccttacac caagaataccaaagaaatctgaaagcctttgaagtatggctggagaaggagcaggaaaaa cttgactgtttatcacatcttgatggtgatgcccaggaacaggaggcaacactccgagat ttacaggagttgcaggtccactgtgcagagggacaagcattattgaatgctgctgtccat gccagagaggaggtgattccctggggtattccccagatagaagacagaactctggaatcc ttacggcaggattggcaagtttatcagcacaggctttctgaagcaagaagccaattaaat gccactgtgagcaaactgaggttaatggagaaaaaatttcagaaggtaaataactggtta accaacctggaggagaaagctgctatcaggactgggaggaggtctggtagagcaacaaaa gaaatgcagcttcaacaaatgaagaagtggcatgaagacattacaatctataaagatgat gtagaggaagttggggtattggctcagcaaatactagaggaaaatctcactgcaagtaga atgggaagtcaggctacgcagcttacatctcgctaccaaactcttcttcttcatgtcttg gagcaagtaaagtttctggaagaggaaatacgctgtttggaggagtcagaattgtccttt agtgcttacacaaattggtatggagctactaacaagaacttcaaaaatgcgattaccaaa tttgacgtggttgataaaacagtaatggagaaaaaagtgcagaaactagaggtgctattg agtgatatggacataggccacagtttactaaaatcagcccgtgagaagggggaacgagct ataaaatacatggaagaaaacaaagttgaccagctaagaaaagaaattggagatcatgtg gaacagcttgaggagctggctggttccatcagaaaagagcacatgacttcagagaaatgt cttcagctggtaaaggagttctcagacaagtataaggcccaaactcagtgggtcatggag taccaagccatcttacatgctcctgtggagccaaagagtgaactctatgagaagaaggca caattgtccaaatacaagtctgtacaacagactgttctgtctcacgagccctcaataaag tcagtgattgaaaagggagaggcactttgtgatctggtgaatgatgtgactctaaagaac agcattcaagaccttcagagcagttaccaggagctctgcagcaaaacaaaggcatacgtt gaaaccctagaggtgagagtaaaagaacatgaggattacaatagtgatttgcaggaaggg gagaaatggttattacatatgtccagcagattggccagccccgacctcatggaaagcaac aatcttgaaataatcactcagcagctagctaaccacaaggctatcatggaagaaattgct ggatttgaagatcgtttgaacaacctcaagagtaaaggtgattacctgatcagtcaatgc tcggaacatcttcaagcaaaatttaagcaaaatatacaaagccatcttcagggcacaagg gacagctattctgccatatgtagcacagcccaaagagtgtaccagactttggaacatgag ctccagaagcatgttaatcatcaggatactcttcaacagtgccagacttggctgtctaca gtgcagtcagagctaaagccacctacttggacacctttcagcctggcagatgcagttaaa caggttaaacatttccgggctctgcaggagcaggccaatacatacttggatcttctgtgc tccatgtgtgatctgtcagacgccacagtgaagagtacagcagcagatattcaacaaacg aaacaaacgattgagcaacagataatgcactcacagtatttgtctcaaggttgggaagag atcaaacaactgaaggctgagctctggatctatttccaggatgcagatcaacaactgcag aatttaaaaaggagacgggcagagttggagctaaatattgcccagaatatggtactccag gttaaggaattcagtcagaagttgcagtctaagcagtcagatctcacctctgtgactgag aagatgaacaaactaacccaagggcaggaatcacctgaacacaaggaaataggagagctg agcaaccagtggctggatctctgccttcagacacatagtttgctcatgcagagggaggag gatctgcagaggacaagggattaccatgatcgcatgaatgtcgttgaagttttcctggaa aagctcacaaaagagtgggacaaccttgctagatctgatgctgaaagtacaaatgtgcac cttgaagctttgcaaaaactggcagttgcactacaggaaaggagatttgctctggaagat ttgaaagatcagaagcagaatatgatagaacatttgaatcttgatgataaagaattagta aaggagcaattcagtcattttgaacagcgctggactcagctggaggaccttgtcaaacgg aaaattcaagtttctgtttcaaccttagaagagctcagcttggtgcattccaaatttcag gaactaatggaatgggcagaggaacagcaacctagtgtctcggaggctcttaaacagagc cctcctccagatatggctcagactcttctcatggatcatcttaccatttgcagtgagctt gaagccaaacagctgcttctgaagatgcttgtgaaggatgctgacagggtgatgaccaac ctagggctcaatgaaaggcaagaactgcagaaaacagtgtctgatgcgcagcaccacgtg gcttgtctcagcgatctggttggccagaggagaaaacacctgaataaagcactgtctgaa aagacccaatttctcatggcagtctttgaggctacaaaccaaattcatcagcatgagaag aaggtgatgtttccagaacacatttgtcttttgccagaagatgtgaataaacaaatcagg acttgtaagaatacccaggctaatctgaaggcctgtcaaaatgaggtcacagggttgtgg gctcaaggaagggatttaatgaaagaagcaacaaatcaagagaagagagaggtgttaggt aaactgcaagaactacagaatgtatacgacactgttttacaaaagtgtaaccagaggttg ttagaactggagaaaaatattgtttccaggaaatatttcaaagaagatttggataaagtt tgccattggctaaaacaagctgatattgtcacattcccagaagtcaatgtaatgaattct aacactgagttacacagccagttggcaaaatatcaacagattcttgagcaatctccagaa tatgaaaatctgctacttacactgcaaagagatggccaagaagtcctaccatcgcttaat gaagtagatcattcttatctagatgaaaaacttaacagcctccctcagcaattcaatatt gtcactgctctggcaaaagaaaagctatataaggttcaggaagccatttacgccagaaaa gagtatgcctctttgatcgagttgacgagtaaagctctgactgagctagaagaccagttt attaacatggacaaagctccagctgctgtctcagccaaagaagctgtgtcactccagcaa gcctacagagatctcttaggtgaagccatgagccttgctgcagcagtggatgaactgaac cagaagaaggaggcttttcgaagcactggccagccctggcagccagatgagatgttaaaa cttgccacactatatcacaagttgaagaggcaaatagaacagaaaattaacctgttggaa gacacaatagaagcatgccaggagcatgagaagatgtgtatgcagtttgaggcacagcta gaagcagtgaaaaaggagcaggttaaggtgaatgaagaaactctcccaatagaagaaaag ttgaaaatataccactctctggtgggcagcttgcaagactcaggaagtcttctgaagcga ataactgaacatctagaaaccctttctcctcaggttgacccatctgcatatgagacaaca aaccaccaagttcaggcttggcaagagaagctgaagtctttgcattctgccattgttgac acggtgatggagtgtgagaacagacttgtgcagagcattgacttcaagacagagatctgc cgctcactcgactggttgaggtgggtgaaaacagaacttaatggaacaataagtttggac ctcaaattgcaaagcatccaagaagaaatccgaaaggttcagatccatcaagaagaagtc cagtcgagcctcagaataatgaatgcactgagcaataaagagaaggagcgctatatgaaa gcaaaggagctgatacctgctgacctggaaaacactcttgctgagctggcagaactggat ggtgaagttcaagaagctatacatgtgagacaggcttccttgaataaagcatatggcctc tgccagaggtactaccaagtgatgcagatagcaaatgactggctggaagatgctcaggaa tttctacaattagcaagaagtggtctagatgttgagaactctgaggagaatctaaggaat catgttgaatttttcataacagaaagtcagtttaacgataatttgaaagtgttacaaggc cttgtgtctgagatagagccctttttacaagccacagcaagcgaacagctggtgcagaat gtagctgcattggaggaaaaggctaaagtgacagagcaagaagctaaaacccagcaagag caattacaaaggtgtgcttctgagtggctggagtaccagacatcaagacagaaggttatt gaagtgatgaatgatgctgagaaaaaattatctgaattctcagtagcaaaagcagcttct tctcatgaagcagaagagaaattactaacacataagactcttgtgtccgtagtgaattct ttccatgagaagatcacagccctagaagagaaggctttgcagctggaaaaaatcagcaat gatgccagtaaggcatctataagtaggtccatgacaacagtttggcagcgctggacacgg ctccggaatgtagcccaggagcaagagaaaattttagaagatgcactgcaggaatggaag ggttttaatgataagattcagaaagccaccatagctatagatcagctacaaggtcgctta ccagaaagctcagtggaaaaggcatccaagacagagctcctggaactcctggattaccac ggcagtttcctgctggaggtggaccaccagctatcatctttgggcctgctcaaacagcat gctgttagcatgcttcaggatgtggaagtaaagactccatctcagaaggaactaccagtt atgcaagaaatcaaggcaatgcaagatcgatgccacaatatgcagcagaaagttaaaaaa ggcatgaagatggtgaaacaggagctgaaggagcgtgaggaggttgaagcagagattaat attgtgaagtcctggatccaggaaacaaaagaatatttattaagtcctgatgcggaagtg gatattcaacttcaggagctgcagtcgctctttggtgaagttgctacacatcgccaggct gttgaaaaactggctgaacaacaacagaataaatacttggggctttataccattttgcct tctgaactctctcttcatttagcagaagttggactggcccttgtaaccgtacaggatcag attcaaaccaaagaaagagaaactcagcaaatcaaaacactgaatcaagagtttgatcag aaaatccaggggatagcaaatgaactaaataccattctttctaaactgaaaaagaaaaca aacgatatagcacaagctaaacttgagcaaaagatccttggtgacgagttggacagctgc aatataaagctgttggaattagatgcatcagtccaggactttgcagagcagaacgtaccc ctggctaagcagctagctaacaggatagggaaactctctgcactgcaccagcagaccata cggcaggctgagtacagagcagccaagctcagtcaggctgcttcacacttggaagaatac aatgagatgctggagttcatattgagatggattgagaaagcaaatatcctagtacatggt agtataacatggaattcttcctctcagcttcgtgatcagtttaaagcctaccagagcatt cttgatgagtctggagagattcacagtgatcttgaggccatgagtgagaggattgattac ctggcaagtgtgtactccactgaaggaatgtcacagcaagtgctggaactagggaggcgg acagaggaattgcagcaagttattaaagtgcagctaccaaacctccaagatgctgccaag gatatgaagaaatttgaaattgagctgagagccctacagggtgctttggagcaagcccaa gccacactgacgtctccggagcttgggcatttgagcttgaaagagcagctttctcacaga cagcatctgttgtctgaaatggagtcactgaagccaaaagttcaggcagtccaagagtgc caaagtgccctgaggattcctgaggaggtggtgaccagcctgcccatgtgccacagtgcc ctgcggctccaggaggaggccagccgcctgcagcacacagccattcagcagtgcaacatc atgcaggaagcagtggttcagtatgagcaatatgagcaagaaatgaaacatttgcagcag atgatagagagtgcccatcgtgagatccaagacaagccaatagcaaccagcaacatccag gagctccaggtccagatttcacgaaatgaggagctggctcagaagatcaaaggataccag gagcaaattgcttctttgaattccaagtgtaagatgctgacaatgaaagcaaaacatgcc accatgctgctgacagtgacagaagtggaggggctgtccgagggaatggaggagctggat tcagacctgctgccagcacaccccactcatccctcggtggttatgatgactgctggtcgc tgtcacactctgctctcccctgtcactgaggagtctggggaggagggaaccaacagtgag atttcttctccacctgcctgtcgctctccctcacctgtggctaatacagatgcttctgtt aaccaggacattgcttattaccaagccttatctgctgaacagttgcagacagaagctgct aaaattcagcccagcacctcagccacccaggagttttatgaaccaggcttagaatcgtct gctagtgccaaattggatgatttgcagcgttcttgggaaacactgaaaaatgtgatcagt gaaaagcagcgcacactctatgaagctcttgagcgtcaacagaagtatcaggacacactc cagtctatatccacgaaaatggagaccactgaaatcaagctaagtgagagtttggaacca gccaaaagcccagagagccagatggctgaacatcaggctttgatggatgagattttaatg ttgcaagaagaaatcagtgagcttcagacatcattggcccaggagcttgtttcagaacca ctggatgcagaaggtgctgatcaaatggcattgcagtccaccctcacagtcttggcagaa cgaatggccacaattcgaatgaaggcatcaggaaaacgacagctattagaggaaaaactg aatgagcagctcgaagaacagcggcaagagcaggctcttcagaggtaccgttgtgaagct gatgagcttgaccactggctactcagtacccgagcaactctggactccgctctgcttcct gccgaagaacctatggacatggaagcacagctggtagactgtcagaacatgttggttgaa atagaacaaaaggtggtagccttgtcagagttgtctgtgcacaacgagaacttgcttatg gaagggaaggctcacaccaaggatgaggcagagcagctggctgtgaagctcaggacactg aagggcagccttctggagctgcagagggtgctccacgacaaacagatcaacattcggcag ggatctttacaagaaaaggaggagagtgatctggactttgtttcctcacaaagccccagt gttcaggaatggctggtgcaagcaagaactactcgctcacagcagcagcagagtaccctg cagcaacagaaagagctggaacaagagctagaagagcagaagaatctgcttcgatcagta gcgtgccgtggaggagagatcctaacgcagcaaggctctaccgaaggcctgtctataagt gagaagcctgatgtactctctgaggaattaaccttagaagttgagaagccatcatctgaa gaacagatgaagaggaaatgggaaagcctaaaccaggaattcagtaccaagcagagactg ctccagaaagctttggaaaaagaacagctgcagctttatagcagaccaaacagactaata cctggaatgcctttgtataaggaggagacacaggacgaagataaatccttagtgtcacca gtgttggttgaattgaatcaggcctttgaagatgtctcatctgaggctggacgggtggag gagaccctgcagcttgagcagaagctgtatgatggtgtcactgccacctccgtgtggctg gatggtgtggaagagcaagtctttgttgctacagctctgttgccagaggaagaaacagaa acctacctctgcaagcaagagtctcttgccaaagaaatcaaagacatcacagaagaagtg gataagaacaagaatttgtttgctcagatatttcctgatagtagtgataagagggttatt atagaagatactttggattgccttctgagaagactgaccttactggagtcagtggttaat cagagatgccaccagatgaaaggacggctccagcaaattatcacattcaagaatgatctg aagctcatgtttacatcggtggctgataacaaatacttggttctacagaaactagcagag gcagctgacagaccagaaacagaacaaatgcaggtcatactgcatgcagaagaaggctta aaggaactagatgctggaatcagtgatttaaagaagcgtatagataagctacaaattgac caaccttctatacaagagttgtctaagatccaggataagtatgatgagctgctgatgatc attggatccaggcggagtgatctgaatcagaatatggctcttaagaggcagtatgagcgg gctttgcaggatctggctgatctggtagaaacaggccaagaaaaaatggctggtgaccag aaaatgattgtttcttccaaggaagaggtccagtcactgcttgaaaaacataaggaatat tttcaagggttggagtctcacatgatcctgacagaaacactttttagaaagatgagtagc cttgccctcttgaaggaaactcagtctcattcagagataatgacacgagcttcggctgta ttaaagctggctcataaacgaggtgtggagctggaatacattctagagacctggatgcat ctggatgaagattaccaggagctcaccagacagctggagtctgttgaaggaaacatcccc actgttggtttggtagaagagacagaagacaggcttacagacaggattacactttttcag catctgagatctaacctgactgaataccagcctaaattataccaagtgctggatgatggg aagaggctccttttttctgttagctgctcagaactcgaaggtcaactgaaccaactagga gaacgctggttaagtaacaccagcaaagtcaccaaggagcttcacaggctggagacaata ctgaagcactggacaaggtatcagagtgaatcaaatgaattgacacagtggttgcaatct gcaaaggagcgacttgagttttggagccagcagtctttgactgttcctcaggaactagaa acagtccgagaccacctgaactcctttttggaattttcaaaagaggtagatgctaaatca tcacagaaatcttctgtcctgagtactgggaaccagctcctcaggcttaagaaagtagat acagctgcattgcgtgcaggattgtcccacatcgaaacccagtggacagagcttctcaca caaatcccagcagtgcaagagaagttacaccagctccagatggacaaaattccttctcgc catgccatcactgaggttatgagctggatttcactgatggaaaatgtaattcagcaggat gaagaaaatataaaaaatgtagtaggacagaaagcaattcagggttacgtccagaagtac aagggtttcaagatagatttaaattgcaaacagttgactgtcgactttgtgaatcaatca gtgctacaaatcagcagccaggatgttgaaagtaaacgcagtgacaaaactgattttgca gaacagcttggagcaatgaacagacgctggcagatcctgcaaggcctgataacagaaaag atccagctcttggaaggtctgcaggaatcctggacagaatatgaaaataatgtgcagtgc ctaaaaatttggtttgaaacccaagaaaagaagctgaaacagcaacaaaaaattggagac caggcttcagtgcagaatgctttgaaagactgtcaggaattagaagaatcaataagagca aaggaaaaagaagtagaaaatgtagaacagagtggtctttctttgatacagaacaagaaa gaagaagtctcttctgctgttatgaatacactgcaagaaattaaccattcctgggccaat ttggatcacatggttagccaactgaagatactgttgcaatctgttcttgatcaatggagc atttataaagtggcttatgaagaactaaacagttacctgacagaagccagatattctttg tcccgtttttatcttcttactggttctctggaagctgtgaaagtccaagttgataaactt cagagcctacaagacgaactggaaaaacaagagaatagcttacagaaatttggttctgtg accaatgaattgttgaaagaatgtcacccaccagtgactgaaacacttaccaacaccttg aaagaagtgaatatgaggtggaacaacctcctgcaggagattgcagagcggctgcgtgcc agcaaggccctgctccagctgtggcagaggtacaaggactgctaccagcagtgctcttcc acagtccaccagcgagaagaccagaccaatgaactcctgaagactgcaaccagcaaagac atcgctgatgatgaagttactacttggattcgggactgcaatgatgtactggcggatttg aaaacagcacaggagtctctggttgttcttcaagagctgggggaggagctaaaaagccag gtggaggcttcagcagcagcagccatacagtctgatcatctctctctgaaccagagtctg acaaccctagagcagactctctgcaagcaacaggctgtgctccaggctggaattctggac tatcaaaccttttccaagagcctggaagtccttgagacctggataacagaagcagaagaa acattgaaagaacaggatcccagtcactcatctgatgtctcagcaatacagagtagaatg gagcaactcaagagtcaaatgctgaagttcagcagcatggcccctgatttggaccgtctt aatgagctgggttacaggcttcctctgaatgacaaggaaatcaaaaggatgcagaacctg aacagacattggtctctgatctcccctcagactacagagagattcagtaagttgcagtct ttcttgctgcagcagcagacgttcttggagaaatgtgggacatggatggatttgttagtt cagactgagcagaagttggcagtagaggtttcaggaaactaccaaaggcttttggagcaa cagagggaacacgagctattccaggcagagatgttcagccgccagcagattttgcattca attatctctgatggccagcacctcctggaacaaggacaggtggatgacagggatgaattt aatctgaatctgactcttctgagtaatcagtggcaaggagtaattcgcagggcacagcag atgagggggatcattgacagccggatccaccagtggcagcgctacagggagatggcagag aagctgcgcaagtggctgctggagatgtcctgtcagccagtgaccgagctgggcactgtt cctatcccattgcagcaagcaagagtgctgctggatgaagtgcagcttaaagagaaagtt ctcctcaggcagcaagggagttacatcctcactgtggaggctgggaagcaactgctgctc tctgctgacagtggagctgaggcagccctgcaggcagagcttactgaaatccaggagcgc tggaagatagttagcactcaactggagcaacaaaagaaacagctggctttgctgctaaaa gactgggaaaaatgtgaaaagggcataggagactccctggagaagctaagatcattcaaa aaaaagctttctcagcctttgccagatcaccatgatgagttgcatgcagagcagattcgt tgcaaggaattagagaatgctgttgaaggctggacagatgaccttacacacctctccctg ctgaaggagactctgtctgtgtatatcagtgcagacgatatctcaatcctgagtgagcga atagagctcctgcacaggcaatgggaggagctgtgccaccaggtctccttgcgtcaacaa caagtgagtgagagactgaatgagtgggctgtcttcagtgagaagaacaaggagctctgt gaatggctgacacaaatggaaagtaaggtgtctcaaaatggtgacatcctcatagaagaa atgattgagaagcttaaaaaggattatcaagaggaaattgctgtcgcccagaagaacaaa atccagcttcaacaaatgggagagagacttgctaaagccagccatgagagtaaggcatca gagattgagtacaaacttggcaagatcaatgacaggtggcagcatcttctagatcttatt gcagccagggtaaagaagttgaaggaaaccctcattgcagtgcagcagctggataaaaac atgagtagtctgagatcttggcttgcccacattgagtcagagctgtccaaacccatcgtc tatgaaacttgtgactctgaggagatacaaaggaagctaaatgagcagcaggaactccag agggacatagaaaaacacagcactggcgtggcatctgttctcaatctgtgtgaagtactt cttcatgactgtgatgcttgtgccacagaagcagaatgtgactctatccagcaagctaca cgcaatttggataggaggtggagaaatatctgtgcaatgtcaatggaaaggcgacttaaa attgaagagacctggcggctatggcaaaaatttttggatgactactctagatttgaagag tggctaaaagcctctgagaggacagctgctttcccaagctcctctggtgtgctttacact gttgctaaggaagagctgaagaaatttgaggctttccagagacaagtgcatgaaagcctg actcagctggagctgatcaataagcagtatcggcgcctggcacgggagaaccgcactgac tccaatggcagcctcaagcagatggttcatgaggggaaccagagatgggacaatctacaa aagcgagttacctccatcctgcgcaggctaaaacattttattggccagcgggaagagttt gaaacggcacgtgacaacatcctggtatggctaacagagatggacctgcagctgaccaac atcgagcatttctcagagtgtgatgtccaagcaaagataaagcaacttaaggctttccag caagaaatttccctgaacaacagcaaaattgagcagataattgtgcaaggtgagcagctc attgagaaaagtgagcccctggatgcagctgtgattgaagaagagctagatgagctgcgt cgttactgccaggaggtcttcgggcgtgtggagcgctatcacaagaaacttatccgcctt cctctaacagatgacgagcacgacctctctgacagagaggtggatctggatgaatcagca gatctctctgacatacgctggcatgacaaatctgcggacagcgttctctccccgcaccct tcttccaacctttcgctgcctctttcccagccgctgaggagtgagcgatcggggcgagat acccctgcgagcgtggactccatccccctggagtgggatcatgactacgaccttagcagg gacctggagacagctgtttcacgggcgctgcactcagaagaagacggaggacaagaaaaa gacttctacctgagaggagcagctggcatagcagatgtagagatccctgaaactctagag gcctatgtaacactcacagaaaacgccctcaaaaatatctctggtgaaccaggtgccctg gaagcacatatccgacagctggacaaggccttggacaccagtcgcttccagatacagcaa acagaaaacatcatccgtagcaagacacctacagggccagaactggattccacttacaga ggatatatgaaactgctaggtgaatgcagtggaagcatagactcagtaagaaggcttgga tataaactgaaggaggaggaagaaaaattttcaggactcattaacatgaacagtactgaa acacaaacagctggtgtaattgaaagatgggaattaatccaggctcaagctctaagcaag gagctgaggatgaagcagaacctgcagcaatggcagcagttcaactccgaccttaatagc atctgggcttggttgggggaaactgaagaggaactggagaagctccaccgccttgatctc agcactgacattcaaactattgaactcagaattaaaaaactaaaagagctgcagaaagca attgacaaccgcaaagcaatcatcttatccatcaatctgtgcagctcagagttcactcag tctgacagtgaggagagcaagaagctccaggagcgcctgtctcagatgaacgtgcgctgg gagcacgtgtgcagcatgatcgaagactggcgcagctcgttgcaggatgcattagtgcag tgccaggatttccatgaactgtgccatggtttattgctttggttggagaatattgacaga aggaaaaatgagattgtgcccatcaacccaaacctggactcagaaatactgcaggatcat cacagacttctgatgcaaatcagacgtgaactgctggagtctcagttgaaggtggcatct ctgcaagatatgtcttgccaattgctagtcaatgctgaaggcaaggattgtcttgaagcc aaagaaaaggtacatgtcattggaaacagactgaagctcctcttgaaagaggttacacgt catattaaagacctagagaaaattctagacatttcaagtagtcagctggaattgtcctca tggtcttccgatgaattagacacatcaggctcagtgagtcctgtatctggaagaagcact ccaagcagacagagaacgccacggggcaaatgtagtctctcacagcctggaccctctgtc agcagtccacatagcaggtccaaaagaggtggttcaggttcctccccttctgaggctggg ccagtgtggcggtgcccgtccttcttcctcagagtcctcagagctgctcttcctcttcag ctcctcctgctgctcctgatcgggctggcgtgcctggtgccaatgaccgaggaggattac agctgtgctatggcaaacaactttgcccgctctttccaccccatgctaaaatacatgaat ggtcctcctccattgtga

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