Peromyscus maniculatus bairdii (prairie deer mouse): 102925488
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Entry
102925488 CDS
T11302
Symbol
Irs2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
pmav Peromyscus maniculatus bairdii (prairie deer mouse)
Pathway
pmav04022
cGMP-PKG signaling pathway
pmav04068
FoxO signaling pathway
pmav04081
Hormone signaling
pmav04140
Autophagy - animal
pmav04152
AMPK signaling pathway
pmav04211
Longevity regulating pathway
pmav04213
Longevity regulating pathway - multiple species
pmav04910
Insulin signaling pathway
pmav04920
Adipocytokine signaling pathway
pmav04923
Regulation of lipolysis in adipocytes
pmav04930
Type II diabetes mellitus
pmav04931
Insulin resistance
pmav04932
Non-alcoholic fatty liver disease
pmav04935
Growth hormone synthesis, secretion and action
pmav05010
Alzheimer disease
pmav05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pmav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
102925488 (Irs2)
04022 cGMP-PKG signaling pathway
102925488 (Irs2)
04152 AMPK signaling pathway
102925488 (Irs2)
09133 Signaling molecules and interaction
04081 Hormone signaling
102925488 (Irs2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102925488 (Irs2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
102925488 (Irs2)
04923 Regulation of lipolysis in adipocytes
102925488 (Irs2)
04920 Adipocytokine signaling pathway
102925488 (Irs2)
04935 Growth hormone synthesis, secretion and action
102925488 (Irs2)
09149 Aging
04211 Longevity regulating pathway
102925488 (Irs2)
04213 Longevity regulating pathway - multiple species
102925488 (Irs2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
102925488 (Irs2)
09164 Neurodegenerative disease
05010 Alzheimer disease
102925488 (Irs2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102925488 (Irs2)
04932 Non-alcoholic fatty liver disease
102925488 (Irs2)
04931 Insulin resistance
102925488 (Irs2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
IRS
PH
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
102925488
NCBI-ProteinID:
XP_006981395
Ensembl:
ENSPEMG00000019911
UniProt:
A0A6I9LLR7
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All DBs
Position
17:59869540..59894576
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AA seq
1336 aa
AA seq
DB search
MASAPLPGPPAPAGGDGPNLNNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDE
AAAAGGSPPLPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKD
EYFAVAAENEQEQEGWYRALTDLVSEGRSGDGGSGIAATGGSCSASLPGVLGGSAGAAGS
DDYGLITPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRV
RTASEGDGGAAAAAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSAGCGGRPSKVTLAPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLPHPLHHPQGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGEFYGY
MSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR
ATFSGSSGRLCPSFPASSPKMAYHPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAAL
RSGGPSSRKSDDYMPMSPTSVSAPKQILQPRSAAAALPPSGAAGPAPPSGPGRTFPVNGG
NNYKANSPAESSPEDSGYMRMWCGSKLSMENADPKLLPNGDYLNMSPSEAGAAAGTPPDF
FSAALRGGGEGLKGVPGHCYSSLPRSYKAPYSCSGDSDQYVLMSSPVGRILEEERLEPQA
TPGTSQLAGAFGAAGGGHTQPHHSAVPSPMRPSGSGGRPEGFLGQRCRAVRPTRLSLEGL
QTLPSMQEYPLPTEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSL
GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTHSGDTVGSMDGLLSPEVSSPYPPLP
PRPSASPSSLQQPLPPAPGELYRLPPAPAATSQGPAAAGPSSSSEPGDNGDYTEMAFGVA
ATPPQPIAAPPKPEGARVASPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADP
QGGRRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGGSGILGGSDEPP
TSPGQAQPSPAVPPAPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVS
DEPGSLSPSQPQHPQPGDKSSWGRTRSLGGLLSSVGSTGASGVCGGPGTGALPSASTYAS
IDFLSHHLKEATVVKE
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atggctagcgcgcccctgcctgggccccccgcgccagcgggcggggacggcccgaacctc
aacaacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaag
cagaagcacggccacaagcgcttcttcgtgctgcgcggccccggcacgggcggcgacgag
gcagccgcggccggggggtcgccaccgctgccgccgcggctggagtactacgagagcgag
aagaagtggaggagcaaggcgggcgcgccgaagcgagtgatcgcgctcgactgctgcctg
aacatcaacaagcgcgcggacgccaagcacaagtacctgatcgccctctacaccaaggac
gagtacttcgccgtggcggcggaaaacgagcaggagcaggagggctggtaccgcgcgctc
accgacttggtcagcgagggtcgctctggcgatgggggctcgggcatcgcggccaccggc
gggtcctgcagcgcctctctcccaggcgtcctgggcggctcggcgggcgccgctggctcc
gatgactacgggctcataacgcccgccacggcagtctaccgcgaggtgtggcaggtgaac
ctgaagcccaagggtctgggccagagcaaaaacctgacgggtgtataccgcctatgcctg
tctgcgcgcaccatcggcttcgtgaagctcaattgcgagcagccgtcggtgacgctgcag
cttatgaacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgc
tcggccgtcaccggccccggcgagctgtggatgcaagccgacgactcggtggtggcgcag
aacatccatgagaccatcctggaggccatgaaggcgctcaaggagctctttgagttccgg
cctcgcagcaagagtcagtcgtccgggtcgtcggccacgcaccccatcagcgtgccgggc
gcgcgccgccaccatcacctggtcaacctaccccctagccagaccggcctggtgcgccgc
tcgcgcaccgacagcctggcggccaccccgccagcagccaagtgcacctcgtgtcgggtc
cgtacggccagtgagggcgacggcggcgcggcggccgcggccgggacggcgggaggcaga
ccgatgtcggtggccgggagccccctgagtcccgggccggtgcgcgcgcccctgagccgc
tcgcacaccctgagcgccggctgcggaggccggccgagcaaagtcacgctggcgccggca
gggggcgccctgcaacacagccgctccatgtccatgcccgtggcgcactcgccgcctgca
gccaccagccccggcagcctgtcctccagcagtgggcacggctcgggctcctacccgctc
ccccccggcccccacccgcatctgcctcatccgctgcaccacccccaaggccagcgtccg
tccagcggcagtgcctccgcgtccggctcccccagtgacccgggtttcatgtcccttgac
gagtatggctccagccctggcgacctgagagccttcagtagccacaggagcaacacgccc
gagtcaatcgcggagaccccgccagctagggatggcagtgggggcgagttctatgggtac
atgagcatggatagacccctgagccactgcggccgcccttaccgtagggtctctggggat
ggggcccaggacctggacagaggactgaggaagaggacttactccctgactacacctgcc
cggcagaggccagtaccccagccttcctctgcctccctggatgagtatactctcatgcgg
gccaccttctctgggagttcaggtcgcctctgcccatctttcccggcatcctctcccaaa
atggcctaccacccttacccagaggactatggagacattgagattggctctcacaagagt
tccagcagtaacctgggggcagatgatggctacatgcccatgacccctggggcggccctc
aggagtggtggccccagtagccgcaagagtgatgattacatgcccatgagccccaccagt
gtatctgcccccaagcagatcctgcagcccaggtcagcggcggcagccttgccgccctca
ggagcagcagggccagcgcccccttcaggaccagggaggaccttcccagtgaacgggggc
aacaactacaaagccaactccccagcggagagctccccagaagatagcggctacatgcgc
atgtggtgtggctccaagctgtccatggagaacgcagacccaaagctgctccccaacggg
gactacctcaatatgtcccccagcgaggctggtgctgccgcgggcacgccacctgacttc
ttctcagcggctttgcgcggaggtggcgagggcctcaaaggtgtccctggccactgctac
agctctctgccccgctcttacaaggccccctattcttgcagtggggacagtgaccagtat
gtgctcatgagctcccctgttgggcgaatcttggaagaggagaggctggaaccccaggcc
accccagggacctcccagttggccggcgcctttggggcagctgggggtggccatacccag
cctcatcactcagcagtgccttcccccatgaggccgagtggtagcggtggccgccctgag
ggcttcctgggccagcgctgtcgggcagtaagacccacgcgcttatctctggagggactg
cagacccttcctagcatgcaagagtaccctctacccacagagcccaagagccctggcgag
tacatcaacattgacttcggggaggcgggcacccgtctgtccccgcctgccccgcctctg
ctggcctcagcggcttcgtcctcctcgctgctttcagccagtagccctgcctcgtccctg
ggttcgggtaccccgggcactagcagtgatagccgccagcgctccccgctctccgactat
atgaacttggacttcagttctcccaagtcccctaagcctggcacccatagtggggacaca
gtgggctccatggatggccttctctccccagaggtctcatccccatacccaccactgccc
cctcgcccttcggcctccccctcttccctgcagcagcctctgccacccgccccgggagag
ctctaccgcctgcctccagcacccgctgccacttcccagggccccgctgctgctggcccc
tcatcgtcctcggagcctggggataatggtgactataccgagatggcctttggtgtggct
gccaccccgccacaacctattgcggcacccccaaagcccgaaggtgcccgagtggccagt
cccacatcgggcttgaagcgcctaagtctcatggatcaggtgtctggggtagaggccttt
cttcaagtcagccagccccctgatccccaccggggtgccaaggtcatccgtgcggaccca
cagggcgggagacgtcgccacagttcagagaccttctcctctaccaccaccgtcacccct
gtgtccccgtccttcgcccacaactccaagcgccacaattcggcctcggtggaaaacgtc
tctctcaggaaaagcagcgaaggcggcagtggcatcctgggaggaagcgatgagccaccc
acatccccgggacaggcacagccctcgccagctgtgccaccggcaccgcaggctaggccg
tggaacccgggccagcccggagctttgattggctgccccggaggcagcagttctcccatg
cgcagagagacctccgtgggtttccagaacggcctcaactatatcgccattgacgtgagt
gatgagccggggtccttgtcgccgtctcagccgcagcatccacagccaggagacaagagc
tcctggggccggacccgtagccttggggggctcctcagctccgtcggaagcactggcgcc
agcggggtgtgtgggggcccaggcactggagccttgccctcagccagcacctacgcaagc
atcgacttcttgtcccatcacttgaaggaagccacagtcgtgaaagagtga
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