Proteus mirabilis HI4320: PMI1045
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Entry
PMI1045 CDS
T00753
Symbol
arnA
Name
(GenBank) bifunctional polymyxin resistance protein [includes: UDP-glucuronic acid decarboxylase and UDP-4-amino-4-deoxy-l-arabinose formyltransferase
KO
K10011
UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:
2.1.2.13
1.1.1.305
]
Organism
pmr
Proteus mirabilis HI4320
Pathway
pmr00541
Biosynthesis of various nucleotide sugars
pmr01100
Metabolic pathways
pmr01250
Biosynthesis of nucleotide sugars
pmr01503
Cationic antimicrobial peptide (CAMP) resistance
Module
pmr_M00761
Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
Brite
KEGG Orthology (KO) [BR:
pmr00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
PMI1045 (arnA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01503 Cationic antimicrobial peptide (CAMP) resistance
PMI1045 (arnA)
Enzymes [BR:
pmr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)
PMI1045 (arnA)
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase
PMI1045 (arnA)
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GFIT
Motif
Pfam:
Epimerase
Formyl_trans_N
GDP_Man_Dehyd
Formyl_trans_C
3Beta_HSD
NAD_binding_10
Motif
Other DBs
NCBI-ProteinID:
CAR42271
UniProt:
B4ETL7
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All DBs
Position
1109779..1111761
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AA seq
660 aa
AA seq
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MKAIVFAYHDIGCVGLKALEKAGFDIQAVFTHTDDPNENHFFSSVARVSAEMGLTVFAPE
NVNHPLWIERIREMKPDVIFSFYYRHMLSDEILNLAPKGAFNLHGSLLPKYRGRAPINWA
IVNGETETGVTLHKMTAKADAGDIVAQEKVTIEDTDTSLILHEKVREAAAKLMAHTLPHI
ASGNYSTTAQDESQATYYGRRCADDGLIDWNADAKTVHNLVRAVTEPYPGAFTFLGERKM
IIWRARPVADNQGKRPGTVISTEPLVIACAKGAIEVITGQSENGLYVQGSRLATEMGIVT
DVRVGPKATAQVKRRQRVLILGVNGFIGNHLTERLLKDGNYDIYGMDIGSSAIERFIGNP
RFHFIEGDVSIHTEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRYC
VKYNKRIIFPSTSEVYGMCDDKEFDEDNSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAK
EGLKFTLFRPFNWMGPRLDNLNSARIGSSRAITQLILNLVEGSPIKLVDGGEQKRCFTDI
NDGIEALFRIIENRDNKCDGQIINIGNPTNEASIRELAEMLLDCFEKHELRGHFPPFAGF
KKIESSSYYGKGYQDVEHRKPSIKNAERLLDWKPTIETRQTVEETLDFFLRGAVEELGNK
NT seq
1983 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcaatagtatttgcctatcatgatattggctgtgttggtttaaaagcacttgaa
aaagcgggtttcgatattcaagctgtatttacccatactgacgatcctaacgaaaatcat
ttcttctcatccgtagcgcgtgttagcgcagaaatgggattaactgtgtttgctccagaa
aacgttaatcatccattatggattgagcgtattcgtgagatgaagccagatgtcattttc
tctttctattatcgccatatgctaagcgatgagatcctgaatttagcacctaaaggtgca
tttaatttacatggctctttattacctaaatatcgcggtcgtgcacctatcaattgggcc
attgtcaatggtgaaactgaaactggtgtcactttacataaaatgacggctaaagcagat
gctggtgatatcgttgcacaagaaaaagtaacgattgaagatactgatacttcattaatt
ttacatgaaaaagtcagagaagctgcggcgaaattaatggctcatacgttaccgcatatc
gcctcaggtaactattcaacaacagcgcaagatgaaagccaagcaacttattatggccgt
cgttgtgctgatgacggtttaattgactggaatgcagatgctaaaacggttcataattta
gttcgcgccgttactgaaccatacccaggtgctttcactttcttaggtgagcgcaaaatg
attatctggcgtgcacgtccagtggcagataaccaaggtaaacgtccgggtactgttatt
tcaactgagcctttagttatcgcatgtgcgaaaggtgcaattgaagttatcacaggtcaa
agtgaaaatggtctttatgttcaaggcagccgtttagccactgaaatggggatcgtgaca
gatgtacgcgttggaccaaaagcaacagcacaagtgaaacgtcgtcaacgtgtactgatt
ttaggtgtcaatggctttattggtaaccacctaaccgagcgtttattaaaagatggtaac
tatgatatctacggtatggatatcggttcatcagcaattgaacgctttattggtaaccct
cgtttccactttattgaaggtgatgtcagcattcatacagaatggattgaatatcacatc
aagaaatgtgatgtgatcttgccattagtagcgattgcaacaccgattgaatatacccgt
aatccattacgtgtatttgaattagattttgaagagaacttaaaaattgttcgttattgt
gttaaatacaataaacgtattattttcccatccacatcagaagtatacggtatgtgtgat
gataaagagttcgatgaagataattcacgcttaatcgtcggtcctattaataaacaacgt
tggatttactctgtttctaaacagttattagaccgagttatttgggcttatggtgctaaa
gaagggctgaaattcactttattccgtccatttaactggatggggccacgtcttgataac
ttaaattcagcgcgtattggtagctctcgtgcaattactcagttaattttgaacctagtg
gaaggttcaccgattaaactggttgatggtggtgagcaaaaacgttgtttcactgatatt
aatgatggtattgaagcattattccgcattattgaaaatcgtgataacaaatgtgatggt
cagatcatcaatatcggtaacccaactaacgaagcaagtattcgtgagctagcagaaatg
ctgttagattgctttgaaaaacatgagttacgcggtcacttccctccatttgctggcttc
aagaaaatcgaaagtagcagttactacggtaaaggctatcaagatgttgaacaccgcaaa
ccaagcatcaaaaatgctgagcgtctattagattggaaaccaactatcgaaacacgccaa
acggtagaagagacattagacttcttcttacgtggtgcagttgaagagttaggtaataag
taa
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