KEGG   Petromyzon marinus (sea lamprey): 116939688
Entry
116939688         CDS       T09614                                 
Symbol
MAP2K1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
pmrn  Petromyzon marinus (sea lamprey)
Pathway
pmrn04010  MAPK signaling pathway
pmrn04012  ErbB signaling pathway
pmrn04068  FoxO signaling pathway
pmrn04140  Autophagy - animal
pmrn04148  Efferocytosis
pmrn04150  mTOR signaling pathway
pmrn04210  Apoptosis
pmrn04218  Cellular senescence
pmrn04270  Vascular smooth muscle contraction
pmrn04370  VEGF signaling pathway
pmrn04371  Apelin signaling pathway
pmrn04540  Gap junction
pmrn04620  Toll-like receptor signaling pathway
pmrn04810  Regulation of actin cytoskeleton
pmrn04910  Insulin signaling pathway
pmrn04912  GnRH signaling pathway
pmrn04916  Melanogenesis
pmrn05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:pmrn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116939688 (MAP2K1)
   04012 ErbB signaling pathway
    116939688 (MAP2K1)
   04370 VEGF signaling pathway
    116939688 (MAP2K1)
   04371 Apelin signaling pathway
    116939688 (MAP2K1)
   04068 FoxO signaling pathway
    116939688 (MAP2K1)
   04150 mTOR signaling pathway
    116939688 (MAP2K1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116939688 (MAP2K1)
   04148 Efferocytosis
    116939688 (MAP2K1)
  09143 Cell growth and death
   04210 Apoptosis
    116939688 (MAP2K1)
   04218 Cellular senescence
    116939688 (MAP2K1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116939688 (MAP2K1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116939688 (MAP2K1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116939688 (MAP2K1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116939688 (MAP2K1)
   04912 GnRH signaling pathway
    116939688 (MAP2K1)
   04916 Melanogenesis
    116939688 (MAP2K1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    116939688 (MAP2K1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116939688 (MAP2K1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pmrn01001]
    116939688 (MAP2K1)
Enzymes [BR:pmrn01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     116939688 (MAP2K1)
Protein kinases [BR:pmrn01001]
 Serine/threonine kinases: STE group
  STE7 family
   116939688 (MAP2K1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 116939688
NCBI-ProteinID: XP_032804312
UniProt: A0AAJ7SRP5
LinkDB
Position
1:complement(26525543..26551277)
AA seq 395 aa
MPAKKKPANLTINPGVVEAPPVINNEGLRPEGPPAAAHGDSEVDREQQKRLDAFLHDKQK
VGELKDDDFQKLSELGAGNGGVVNKVLHRPSGIIMARKLIHLEIKPAIRTQILRELQVLH
KCNSPYIVGFYGAFYIDGEISICMENMDGGSLDLVLKKARRIPEKILGKVSIAVIRGLAY
LREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTN
YSVQSDVWSMGLSLVEMAIGRFPIPPPEPRELEAIFGKAVADGAGGSSAPRPRPPGRPIS
SFGGGGGAPMAIFELLDYIVNEPPPKLPPGIFSQEFQDFVNKTLIKNPAERADLKTLMAH
PFIRGAEAEEVDFAGWLCSTIGLQPPATPTQPATQ
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgcctgccaagaagaagccggccaacctcaccatcaacccaggtgtggtggaagctcca
ccggtcatcaacaacgagggcctgaggccagagggccctcccgctgcggcgcacggggac
tcggaggtcgaccgtgagcagcagaagcgcctggacgccttcttgcacgacaagcagaag
gtgggcgagctcaaggatgacgacttccagaagctgagcgagctcggcgccgggaacggc
ggcgtggtcaacaaggtgctgcacaggccctccggcatcatcatggcgcgcaagttgatc
cacctggagatcaagccggcgatccgcacgcagatcctgcgcgagctgcaggtgctgcac
aagtgcaactcgccgtacatcgtgggcttctacggcgcattttatatcgacggcgagatc
agcatttgcatggagaacatggatggtggctcgttggatttggtcttaaagaaggctcgc
agaatcccagaaaagatcctgggcaaagtcagcatcgccgtgattcgagggctggcttac
ctccgcgaaaaacatcagattatgcacagagacgtgaagccgtcgaacatcctggtgaac
tcgcgcggggagatcaagctgtgcgacttcggcgtgagcggccagctcatcgactccatg
gccaactcgtttgtggggacgcgatcgtacatgtcgcccgagcgcctgcagggcactaac
tactcggtgcagtcggacgtgtggagcatgggcctctcgctcgtggaaatggccatcggc
cgcttccccatcccgccgcccgagccccgtgagctggaggccatctttggcaaggcggtc
gcggacggcgccgggggatcgtcggcccccagacccagacccccgggccgccccatcagc
tcttttggtggaggaggaggagcaccgatggcaatttttgaacttctggactacatcgta
aatgagcctcctcccaagctgcccccgggcatcttcagccaggaattccaggactttgtc
aataaaactttgataaagaatcctgctgaacgcgccgacctcaagactctaatggctcac
ccgttcatccgtggagcggaggcggaggaggtggattttgccggctggttgtgcagcacc
atcggcctccagccacccgccacccccacacagcccgccactcagtaa

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