Petromyzon marinus (sea lamprey): 116954501
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Entry
116954501 CDS
T09614
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like isoform X1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pmrn
Petromyzon marinus (sea lamprey)
Pathway
pmrn00140
Steroid hormone biosynthesis
pmrn01100
Metabolic pathways
Module
pmrn_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pmrn_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pmrn_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pmrn00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
116954501
Enzymes [BR:
pmrn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
116954501
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
116954501
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
KR
adh_short
Motif
Other DBs
NCBI-GeneID:
116954501
NCBI-ProteinID:
XP_032830946
UniProt:
A0AAJ7U747
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Position
3:complement(14557556..14567253)
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AA seq
398 aa
AA seq
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MEGPTAPTDQGPLQGDSSGPVPPPHVYVVTGGAGFLGGFLTPQLLELGEEVAEVRLVDCA
FKGDEILSYPEAVRGKIRVIQADIRDERAMRAACRGAHVLLHTASLIDVWDRNSEAEIFS
VNQHGTHVLLEACVHEGVSVAIYTSSVEVAGPNGQGDPIVNGDEETPYKHNLCFTYSRSK
AEAERLTLSYDGAALPGGGTLTTCALRPMYIYGERCRFLRFHITNGLANGRVLLRGSRPS
ALVNPVYVGNVAHAHVLAARLALTGGTEAERRRPGGRVYYVSDDTPPISYSDFNYMVARD
LGFGIQKRLPMPFVVLYAVAALLELLRFLMRPFYKFVPPINRQLVVMVNTHFTFKHERAR
RELGYKPRFSWEEAHARTTEWLAKEVPLIEAELKQNKK
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
atggaggggcccacagcgcccacggaccagggccccctgcaaggggactcgtcgggcccc
gtgccgcccccgcacgtgtacgtggtgacgggcggtgcgggcttcctgggcggcttcttg
acccctcagctgctggagctcggggaggaggtcgccgaagttcgactcgtagactgcgcc
ttcaagggcgatgagattttgtcctatccagaggccgtgcgaggcaagatccgcgtgatc
caggccgacatccgcgatgagcgtgcgatgcgggcggcgtgccgaggcgcccatgtcctc
ctgcacacggcctcgctcatcgacgtgtgggaccgcaacagcgaggcagagatcttttcc
gtgaaccagcacggcacgcatgtgctattggaggcctgcgtgcacgagggtgtgagcgtc
gccatctacaccagctccgtggaggtggccgggcccaacgggcagggtgaccccattgtc
aatggcgacgaggagaccccgtacaagcacaacctctgtttcacctacagccgcagcaag
gcagaggccgaacgtctcacgctgtcctacgacggcgcggctctaccgggcggcggcacc
ctgacgacgtgcgctctgcggcccatgtacatctacggcgagcgctgccgcttcttgcga
ttccacataaccaatggcctcgccaacgggcgcgtgctgctgcgcgggtcgcgccccagc
gccctcgtgaatcccgtctacgtcggcaacgtggcgcacgcgcacgtgctggcagcacgc
ctggcactgacgggcggcaccgaggcggagcgacgtcgccccggcgggcgcgtctactac
gtgtcggatgacacgccgcccatcagctactcagatttcaactacatggtggcgcgcgac
cttggcttcggcattcagaagcggctgccgatgccgttcgtcgtcctatacgccgtggcg
gccctgctcgagctgctccgcttcttgatgcggccgttctacaagttcgtcccacccatc
aaccgtcagctcgtggtcatggtcaacacgcacttcacgttcaagcacgagcgcgcgcgg
cgcgagctgggctacaaaccccgcttctcgtgggaggaggcgcacgcccgcaccaccgag
tggctcgccaaggaggtgcccttgatagaggctgagctgaaacaaaacaagaaataa
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