Podarcis muralis (common wall lizard): 114587929
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Entry
114587929 CDS
T06059
Symbol
HSD3B2
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pmua
Podarcis muralis (common wall lizard)
Pathway
pmua00140
Steroid hormone biosynthesis
pmua01100
Metabolic pathways
Module
pmua_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pmua_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pmua_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pmua00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
114587929 (HSD3B2)
Enzymes [BR:
pmua01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
114587929 (HSD3B2)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
114587929 (HSD3B2)
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Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
PRO8NT
Motif
Other DBs
NCBI-GeneID:
114587929
NCBI-ProteinID:
XP_028568645
UniProt:
A0A670JTK3
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Position
17:2856672..2865640
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AA seq
377 aa
AA seq
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MSLAGMKCLVTGAGGFLGQRIVCQLLEEEEGLAEVRATDKALSPETLQRFGKLKTKTPLT
IIQGDIRDAAFLRTATQGVSLVIHTACIIDVLGYIDKQTLWDVNTKGTQLLLDACFHNNV
QYFVFTSSIEVMGPNRRGDPIVDGDEDTVYHDTRKFPYAESKRVAEKFVQQLDGQPLKDG
SSLVTCALRSPYIFGEGSPFLLGHLDESIQNNNVFIRLSRKEALVNPIYVGNIASAHIQV
AKAMRDPEKVKRIRGKFYYITDDTPHMSYSDLNYELSKELGFGIEPKLPMPLTMFYYYSL
LLEIVSFLLRPFVRYIPRINTHLVTLVNTPFSFSSRKAQRDFGYAPRYKWEEAKELTSQW
IAKVAPLRRAYLKNKTL
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtctttggcaggaatgaaatgcctggtgaccggagctggtggattccttggtcaaagg
atcgtctgccagttgctggaggaagaggaaggactggccgaggtccgcgccacggacaaa
gccctcagccctgagacgcttcagcgttttggaaaactgaagactaaaactcccttgaca
atcatccaaggggatatccgggatgcagcgttcctccgcacggctacccaaggtgtctct
cttgtcatccacacggcttgcatcatcgacgtcttgggatatatagacaaacagacactt
tgggatgtcaacacgaaaggtacacagctgctcctggatgcctgcttccacaacaacgtc
cagtattttgtcttcaccagcagcattgaagtgatgggtccaaacagaagaggggacccc
attgttgatggcgatgaagacacggtgtaccacgataccagaaaatttccttacgctgaa
tcaaagagagtagcggagaaatttgtgcagcagctggatggccagccactgaaagatggc
agcagtcttgtgacgtgcgctttgaggtccccgtacatctttggagaaggaagtcctttc
cttctgggccatctcgatgaaagcatccaaaacaataacgtctttataaggctatctagg
aaggaggctctcgtaaatcccatctacgtagggaacattgcttcggctcacattcaagtg
gcgaaagccatgagggatccagaaaaggtcaagcggatccgaggaaaattctattacatc
acagatgacactccccacatgagctattcggacttaaattatgagctgagcaaggagctg
gggtttggtattgaacccaaactaccaatgcccttgacaatgttctattactattctctg
ctgctggagattgtgagtttcttactccggccttttgtcagatacattccccgcatcaac
actcaccttgtgaccttggtcaataccccgtttagcttttcttccagaaaagctcaaagg
gattttggctatgcacctcgctacaaatgggaagaagccaaggagcttacaagccagtgg
attgccaaagtagctccactgagaagggcctacctgaaaaacaagaccctctaa
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