Protobothrops mucrosquamatus (Taiwan habu): 107285816
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Entry
107285816 CDS
T05763
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pmur
Protobothrops mucrosquamatus (Taiwan habu)
Pathway
pmur00140
Steroid hormone biosynthesis
pmur01100
Metabolic pathways
Module
pmur_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pmur_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pmur_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pmur_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pmur00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
107285816
Enzymes [BR:
pmur01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
107285816
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
107285816
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
adh_short
Motif
Other DBs
NCBI-GeneID:
107285816
NCBI-ProteinID:
XP_015669554
LinkDB
All DBs
Position
Unknown
AA seq
377 aa
AA seq
DB search
MSLGGMRCLVTGAGGFLGRRIVCQLLTEKESLAEVRILDKTVSAEALQDFEKVKSNTLLT
VIQGDIRDVALLQTAVQGVSLVIHAAAIIDTRGLIDRQTLWDVNVRGTQLLLETCLRNDV
QYFIYTSSLEVTGPNNRGDPISDGDEDTIYQMTQGPPYAETKREAEKCVLELDRLPLKGG
NSFVTCALRPMYIYGEGSPFLLSHLDESILNNNVFLRLSRKEAIVNPVYVGNIAWAHIQV
AKAMRNPTKVKLIRGRFYYISDDSPHTSYSDFNYELTKELGFGVEPKPVMPITLFYYYAL
FLEIVSFLLKPFLRYVPAINRSLVVLLNTPFSFSYKKAQKDFNYTPHYSWEEAKQRTSRW
IADITPLRAAYLKSKTT
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtccttgggaggaatgaggtgcctcgtgactggtgctggtgggttcctaggtcgaagg
attgtttgccagctgctgacagaaaaggagagtttggccgaagtcagaatcttggacaaa
accgtcagtgctgaagcactccaggattttgagaaagtgaaaagtaacacccttttgaca
gtcatacaaggggatatccgggatgtggcgcttcttcaaacagcagtccaaggagtctcg
cttgtcatccatgcagctgccatcattgacacccgggggctcatcgatcgacagaccctc
tgggatgtcaatgtcaggggtacacagttgctgctggagacttgcctccgcaatgatgtc
cagtattttatttataccagcagccttgaggtgacagggccaaacaacagaggggatccc
atctctgacggtgatgaagacaccatatatcagatgacccaaggcccaccctatgctgaa
actaaaagagaggcagagaaatgtgtcctggagctggacaggttgccactcaaggggggc
aatagttttgtaacatgtgctttgaggcccatgtacatctatggagaaggcagtcctttc
cttctgagtcacctcgatgaaagcatcctgaacaataatgtatttttgaggctgtctagg
aaagaggcgattgtaaatcctgtctatgtgggaaatattgcttgggctcatattcaagtg
gctaaagccatgagaaacccaacaaaagtgaaactgatccgagggcgtttctactatatc
tcggatgattctccccacacaagctattccgacttcaattatgagctgacaaaggagttg
ggctttggtgttgaacccaaacctgtgatgcccattacacttttttattattatgctctg
ttcctggagattgtgagcttcttgctcaaacctttcttgagatacgttcctgctattaat
cgttcccttgtagtcctgctcaacaccccattcagtttttcttacaagaaagcacaaaag
gattttaactatactcctcactactcctgggaagaggccaaacagcgaacaagtcgatgg
attgctgacataacccctctgagggcagcatatctgaaaagcaagactacctga
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