Pseudomonas aeruginosa NCGM2.S1: NCGM2_2758
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Entry
NCGM2_2758 CDS
T01974
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
pnc
Pseudomonas aeruginosa NCGM2.S1
Pathway
pnc00270
Cysteine and methionine metabolism
pnc00450
Selenocompound metabolism
pnc00670
One carbon pool by folate
pnc01100
Metabolic pathways
pnc01110
Biosynthesis of secondary metabolites
pnc01230
Biosynthesis of amino acids
pnc04980
Cobalamin transport and metabolism
pnc04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pnc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCGM2_2758 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
NCGM2_2758 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCGM2_2758 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
NCGM2_2758 (metH)
04980 Cobalamin transport and metabolism
NCGM2_2758 (metH)
Enzymes [BR:
pnc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
NCGM2_2758 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAK89610
LinkDB
All DBs
Position
1:complement(2931865..2935569)
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AA seq
1234 aa
AA seq
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MSSPLTDRSARLQALQHALRERILILDGGMGTMIQSYKLEEADYRGERFADWPSDVKGNN
DLLLLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADYGMQSLAYELNVEGARLARQ
VADAKTAETPDKPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEATRGLIEG
GADLILIETIFDTLNAKAAIFAVQGVFEELGVELPIMISGTITDASGRTLSGQTTEAFWN
SVRHARPISVGLNCALGAKELRPYIEELSTKADTHVSAHPNAGLPNAFGEYDESPAEMAV
VVEEFAAAGFLNIVGGCCGTTPAHIEAIAKAVAKYPPRAIPEIPRACRLSGLEPFTIDRS
SLFVNVGERTNITGSAKFARLIREENYAEALEVAQQQVEAGAQVIDINMDEGMLDSKAAM
VTFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEAFKHHARLC
KRYGAAVVVMAFDEDGQADTQARKEEICKRSYDILVDEVGFPPEDIIFDANIFAIATGIE
EHNNYAVDFINACAYIRDHLPYALSSGGVSNVSFSFRGNNPVREAIHSVFLYYAIRNGLT
MGIVNAGQLEIYDEIPKALRDRVEDVVLNRTPEATEALLAIADDYKGGGAVKEAEDEEWR
SYSVEKRLEHALVKGITTWIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFL
PQVVKSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNG
YDVVDLGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQNFQLPLMIGG
ATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATSLLSKELKADYVARTRADYAVVRER
TANRSARTERLSYEQAIANKPAFDWAGYQAPTPSFTGVRVLDEIDLAVLAEYIDWTPFFI
SWDLAGKYPRILTDEVVGEAATSLFNDAQAMLKKLIDEKLIKARAVFGFWPANQVEHDDL
EVYGADGETLATLHHLRQQTIKPDGKPNLSLADFVAPKESGVRDYIGGFITTAGIGAEEV
AKAYEAKGDDYNSIMVKALADRLAEACAEWLHERVRKEYWGYARDEHLDNEALIKEQYVG
IRPAPGYPACPDHTEKGTLFELLDPQGLSGVSLTEHYAMFPAAAVSGWYFAHPQAQYFAV
GKIDKDQVERYSQRKGQEASVSERWLAPNLGYDD
NT seq
3705 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcccgctcaccgatcgcagcgcccgcctgcaagccctccagcacgccctcagg
gaacgtatcctgatcctcgatggcggcatgggcaccatgatccagagctacaagctggaa
gaagccgactaccgcggcgagcgcttcgccgactggccgagcgacgtgaaaggcaacaac
gacctcttgctgctcagccgcccggacgtgatccaggccatcgagaaggcctacctcgac
gccggcgccgacatcctcgagaccaataccttcaacgccacccaggtgtcccaggccgac
tacggcatgcagtcgctggcctacgaactcaacgtcgaaggggcgcgcctggcccgccag
gtggcggacgcgaagaccgccgagaccccggacaagccgcgcttcgtcgccggcgtgctc
ggcccgaccagccgcacctgctcgatttccccggacgtgaacaaccccggctaccgcaac
gtcaccttcgacgagctggtggagaactacgtcgaggcgacccgcggcctgatcgagggc
ggcgccgacctgatcctgatcgagaccatcttcgacaccctcaatgccaaggcggcgatc
ttcgccgtccagggcgtgttcgaggaactcggcgtggagctgccgatcatgatctccggg
accatcaccgacgcctccggccgcaccctgtcgggccagaccaccgaggccttctggaac
tcggtgcggcatgcccggccgatctcggtaggcctgaactgcgccctcggcgccaaggaa
ttgcggccgtacatcgaggaactgtcgaccaaggccgacacccatgtctcggcccacccc
aacgccggcctgccgaacgccttcggcgaatacgacgaatcgccggcggaaatggccgtg
gtggtcgaggaattcgccgccgccggcttcctcaatatcgtcggcggctgctgcggcacc
accccggcgcacatcgaggcgatcgccaaggcggtggccaagtacccgccgcgggccatc
ccggagattccccgggcctgccgcctgtccggcctggagccgttcaccatcgaccgcagc
tcgctgttcgtcaacgtcggcgagcgcaccaacatcaccggctcggccaagttcgcccgg
ctgatccgcgaggaaaactacgcggaagccctcgaggtcgcccagcagcaggtggaagcc
ggcgcccaggtgatcgacatcaacatggacgaaggcatgctggactcgaaggcggccatg
gtcaccttcctcaacctgatcgcctccgagcccgacatctcgcgcgtgccgatcatgatc
gactcctccaagtgggaggtgatcgaggccggcctcaagtgcatccagggcaagggcatc
gtcaactcgatctcgatgaaggaaggcgtcgaggccttcaagcaccatgcccgcctgtgc
aagcgctacggcgccgcggtggtggtgatggccttcgacgaggacggccaggccgacacc
caggcgcgcaaggaagaaatctgcaagcgctcctacgacatcctggtcgacgaagtcggc
ttcccgccggaagacatcatcttcgacgcgaacatcttcgccatcgccaccggcatcgag
gaacacaacaactacgcggtcgatttcatcaacgcctgcgcctacatccgcgaccacctg
ccctacgccctcagctcgggcggggtgtccaacgtgtccttctcgttccgcggcaacaac
ccggtacgcgaggcgatccactcggtgttcctctactacgcgatccgcaacggcctgacc
atgggcatcgtcaacgccggccagctggaaatctacgacgagatcccgaaggcgctgcgc
gaccgggtcgaggacgtggtgctcaaccgcacgccagaggccaccgaggccctgctggcg
atcgccgacgactacaagggcggcggcgcggtcaaggaggccgaggacgaggaatggcgc
agctacagcgtcgagaagcgcctcgagcatgcgctggtcaagggcatcaccacctggatc
gtcgaggacaccgaggaatgccgccagcagtgcgcgcgccccatcgaggtcatcgaaggt
ccgctgatgtccgggatgaacgtggtcggcgacctgttcggcgccggcaagatgttcctc
ccgcaggtggtcaagtccgcgcgagtgatgaagcaggcggtggcccacctgattcccttc
atcgaggcggagaaaggcgacaagccggaagccaagggcaagatcctgatggccacggtg
aagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtgctcggctgcaacggc
tatgacgtggtcgacctcggcgtgatggtgccggcggagaagatcctgcagaccgccatc
gccgagaaatgcgacatcatcggcctgtccggcctgatcacgccgtcgctggacgagatg
gtccacgtcgccaaggaaatgcagcggcagaatttccagttgccgctgatgatcggcggc
gccaccacctcgaaggcgcataccgcggtgaagatcgatccgcagtacagcaacgacgcg
gtggtctacgtcaccgacgcctcgcgcgcggtaggcgtggccaccagcctgctgtccaag
gagctgaaggccgactacgtggcccgcacccgcgccgactacgcggtggtccgcgaacgc
acggccaaccgcagcgcccgcaccgagcggctgagctacgaacaggcgatcgccaacaag
ccagcgttcgactgggccggctaccaggcgccgacgccttccttcaccggcgtcagggtg
ctcgacgagatcgacctcgcggtgctcgccgagtacatcgactggacgccgttcttcatt
tcctgggacctggccggcaagtacccgcgcatcctcaccgacgaggtggtcggcgaggcc
gccacctcgttgttcaacgacgcccaggcgatgctgaagaagctgatcgacgagaagctg
atcaaggcccgcgcggtgttcggcttctggccggccaaccaggtcgagcacgacgacctg
gaggtctacggcgccgacggcgagaccctcgccaccctgcaccacctgcggcagcagacg
atcaagccggacggcaagccgaacctgtcgctggccgatttcgtcgcgccgaaggaaagc
ggcgtgcgcgactacatcggcggcttcatcaccaccgccgggatcggcgccgaggaagtg
gccaaggcgtacgaagccaagggcgacgactacaacagcatcatggtcaaggcgctcgcc
gaccgcctcgccgaagcctgcgccgagtggctgcacgagcgggtgcgcaaggagtactgg
ggctacgcccgcgacgagcacctcgacaacgaggccttgatcaaggagcaatacgtcggc
atccgcccggcaccgggctacccggcctgccccgaccataccgagaaaggcaccctgttc
gaactgctcgatccgcagggcctgtccggcgtcagcctgaccgagcactacgcgatgttc
ccggccgcggcggtcagcggttggtatttcgcccacccgcaggcgcagtacttcgcggtc
ggcaagatcgacaaggaccaggtggaacgctacagccagcgcaagggccaggaagccagc
gtcagcgagcgctggctggcgccgaaccttggctacgatgactga
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