KEGG   Candidatus Protochlamydia naegleriophila: PNK_2312
Entry
PNK_2312          CDS       T04212                                 
Symbol
putA
Name
(GenBank) bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase)
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
pnl  Candidatus Protochlamydia naegleriophila
Pathway
pnl00250  Alanine, aspartate and glutamate metabolism
pnl00330  Arginine and proline metabolism
pnl01100  Metabolic pathways
pnl01110  Biosynthesis of secondary metabolites
Module
pnl_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:pnl00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    PNK_2312 (putA)
   00330 Arginine and proline metabolism
    PNK_2312 (putA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:pnl03000]
    PNK_2312 (putA)
Enzymes [BR:pnl01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     PNK_2312 (putA)
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     PNK_2312 (putA)
Transcription factors [BR:pnl03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    PNK_2312 (putA)
SSDB
Motif
Pfam: Aldedh Pro_dh
Other DBs
NCBI-ProteinID: CUI17910
UniProt: A0A0U5JJD5
LinkDB
Position
cPNK:complement(2709746..2713411)
AA seq 1221 aa
MEESSLIAKANAQIQSVKGKTLSSQERCEASVTLAATMLEEAQQIQTAAEKRQQAELAGM
MNDPIGKIFTTAITDQCFRSQRSSRVADQLVHVIKKYGVPKYLSADKRLALQAFTLVGKF
LSPAIVPLTIQLIRKETNNVILPGEEKALAKHMQKRRQEGVRINLNHLGEAILGEEEAHH
RLQIYLNDLIKPSVEYISIKISTIYSQINLLAWDETLEILADRLRQLYRAAMKNRYVRAD
GRSVPKFVNLDMEEYRDLHLTVALFRKVLNEPEFYQHEAGIVLQSYLPDSFLIQQELTVW
AMQRLVQGGGPIKIRIVKGANLAMEQFEAALRLWPQAPYNTKADVDANYKRMVTYGCEKE
HAQAAHLGIASHNLFDIAYAMLLRAENGVEKEVCFEMLEGMADNIRRVVQKLSGDMLLYC
PAATKAEFQNAVAYLVRRLDENTAPENFLRHVFDLKPGTEQWQQQVNLFSQACQNYKQVS
YKPRRHQNRLSEESALKEGYCFQNVADTDWSLPANRKWAQKIIEEWKHKKHKPVPLVING
HYYVPEGVKGIGEDPSYPGQTLYNYALATKQHVDQALQTAQEAQKNWSETSVEERAHVLA
KIAQGMEKHRGKLIGAMIADTGKTIQEADIEVSEAIDFANYYRLSLLEWAQLPDIKWKSK
GVVLVAPPWNFPCSIAAGGILAALATGNTVIFKPAAEAVLVDWYLAQIFWEAGITQQVLQ
FITCEDDPVGSQLIQDPRVALVVLTGATETAKLFLRLRPNLDLMAETGGKNTMVITAICD
RDLAIKDLIHSAFGHAGQKCSACSLAILEAEVYDDPHFRKQLRDAAASMIVGSPWSLKTK
MNPLIRAAHPALLRGLTTLEEGEEWLLEPKQDPVNPHLWSPGIKLGVKPKSFTFETELFG
PVLGLVRAATFEDALTMMNQTAYGLTAGIHSLDEREQEKWLKQIEAGNCYINRTVTGAVV
ERQPFGGCKDSSFGKGSKAGGPNYLVQFMQAEQFALPAEEEELSGAILDFFKAVANQELL
TSPQEKAIWNSSVKSYAFYWNHYFSKKHDPSLVMGQDNLQCYKPHETILLRGRTDDSLLD
LLRVTAAAIVCSTPLDVSLEDESLYNQIRKLNLSGSIKVRHESELALMQRVKKGEIKRVR
LLGPVSAQLQEALAHAACHINAGAVLANGRLELLHLLREVSISRDYHRYGNLGDREKEKR
HPLPGCEGEQSSPCGACVCHG
NT seq 3666 nt   +upstreamnt  +downstreamnt
atggaagagtcctccctcatagcaaaggctaatgctcaaatccaatcagttaaaggcaaa
acgctttcttctcaagaaaggtgtgaagcttcggtgactttagcagcgacgatgttagag
gaggctcagcagatacaaacggcggcagagaaacggcaacaggccgagcttgcggggatg
atgaacgacccgattggcaagatttttaccactgctattaccgatcaatgtttccgtagc
cagcgttctagtcgagtggcagatcaattagtccatgttatcaaaaagtatggtgttccc
aagtatttatcggccgataagcgattggctttgcaagcctttacgttggttggcaaattt
ttatctccagcaattgttcctttgactattcagcttattcgcaaagagactaataacgtc
attttgcctggtgaagaaaaggctcttgccaagcacatgcaaaaaaggaggcaggaaggg
gttcgaatcaatttgaaccacttaggagaagctattttaggggaagaggaggcacatcat
cgcctgcaaatttatttaaatgatttgatcaagccttctgtcgaatatatctccatcaag
atttcaacgatctatagccaaatcaatttactggcttgggatgagacgttagagatattg
gccgatcgtttgcgccaattatatagggctgccatgaagaatcggtatgtgcgggcagat
ggccggtcggttcctaagtttgtcaatttagacatggaagaatatcgcgacctgcatttg
accgtggctcttttccgcaaagtgttgaacgaacccgaattctatcagcatgaggctgga
attgtcctgcaaagttatttaccagactcgtttctcattcaacaagagctgactgtgtgg
gccatgcagcgattggtacaagggggggggccgataaagattcgcattgtaaaaggtgcc
aatctggctatggagcagtttgaagccgctcttcgcttatggccgcaggctccttacaat
acgaaggccgatgtggatgccaattataagcggatggttacttatggctgtgaaaaagaa
catgcacaggcggctcacttgggaattgcgagccataatttatttgacatagcttatgca
atgcttctaagagccgaaaatggggttgaaaaagaggtgtgctttgagatgttggaggga
atggccgataacatccgccgtgttgtacaaaaattgtctggagacatgctcctttattgt
cctgccgctactaaagctgaatttcaaaacgcggtggcctatttagtgcgccgcctggac
gaaaatacggcaccggagaatttcttgcgtcatgtcttcgatctcaagcctggtaccgaa
caatggcagcaacaggttaacttattctcccaagcatgccaaaactataagcaggtctct
tataagcctagaaggcatcaaaaccgtctgtctgaagaatccgccttaaaagaagggtat
tgctttcaaaacgtagctgataccgattggtctttgccagctaaccgcaagtgggctcaa
aaaattattgaagagtggaagcacaagaagcataagccggttcctttagtcatcaatgga
cattattatgttccggaaggtgtcaagggaattggagaagatccatcttatccaggccaa
acgctttacaactatgctttagcaactaagcaacacgtcgatcaagccctgcaaacggct
caagaagctcaaaaaaactggtctgagacctctgttgaagaaagggcgcatgtgcttgcc
aagattgcccaggggatggaaaagcatcggggaaaattgattggggctatgattgccgat
acgggcaaaacaattcaggaagccgacattgaagtgtcagaggcaatcgatttcgccaac
tactatcgcttgagcctcttagaatgggcgcagttgccagatataaagtggaagtcgaaa
ggagtcgtgcttgtggcgcctccttggaactttccttgctcaattgctgcgggaggtatt
ctggcagccttggcaaccggcaatacggtgatctttaagccagcagcagaagccgtttta
gtcgactggtatttggctcaaattttttgggaagcgggcatcactcaacaagttttgcaa
ttcatcacgtgcgaagatgatccggttggcagccaactcattcaagatccacgcgttgcg
ttggtggtgttgactggtgcaaccgaaacagctaaactctttttgcgcttaagaccgaat
ttagatttgatggccgaaacgggtggaaaaaatacgatggtgatcacggctatttgcgat
agagatcttgccatcaaagatttgatccattcagcttttggacatgcagggcaaaagtgc
agtgcttgcagtttggcaattttagaggctgaggtatacgatgatccccatttccgcaag
caactgcgcgatgctgcagctagcatgatcgttggttccccttggagtttaaaaaccaag
atgaatccactcatcagagcggctcatcctgcactgctgcgaggcttgacaaccctggaa
gaaggggaagagtggctattagaacccaagcaggatccagtcaatcctcatctgtggagt
cctggcatcaaactaggcgtcaaacccaaaagcttcacctttgaaaccgagctcttcggt
ccagttttggggctggtgcgagcagcgacgtttgaagatgctttaactatgatgaatcaa
acggcttatgggttaacggcgggcattcattccttggatgaacgggaacaagaaaagtgg
ttaaagcaaatcgaagcgggcaattgttatatcaatcgtaccgtgacgggcgccgtagtc
gaacgccagccttttggaggatgcaaagacagcagctttggcaaagggtcgaaagcaggc
gggccgaactaccttgtccagtttatgcaggccgagcagtttgctttaccagcagaggaa
gaggagctaagcggtgcgatcttggactttttcaaagcggtagctaatcaggagctccta
acaagcccgcaagaaaaagccatttggaacagcagtgtgaagagctatgcattttattgg
aatcattatttttcgaagaagcacgatccaagcctcgtgatggggcaagataatttgcag
tgctataagccgcatgaaaccattttgctgagaggcagaacggatgattccttgcttgat
cttttaagagttacggcagctgccatagtgtgctcaacgccgcttgatgttagccttgaa
gatgagagcctatataatcagatcaggaagcttaatctttcaggctctattaaggttagg
catgaatcagagcttgctttaatgcagagagtgaaaaaaggtgaaatcaagcgtgtgcgc
ctactaggaccagtttcagcgcagttgcaagaagccttggcgcatgcagcttgccatatc
aatgcaggcgcagtattagccaatggaagattagagttattacacctcttaagagaggtg
agtatcagtcgcgattatcatcgctatggaaatttaggtgatagggaaaaagagaagcgg
caccccttgccaggatgtgaaggggagcagtcttcgccgtgtggagcatgtgtgtgtcat
ggataa

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