KEGG   Polaromonas sp. JS666: Bpro_0174
Entry
Bpro_0174         CDS       T00343                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
pol  Polaromonas sp. JS666
Pathway
pol00270  Cysteine and methionine metabolism
pol00450  Selenocompound metabolism
pol00670  One carbon pool by folate
pol01100  Metabolic pathways
pol01110  Biosynthesis of secondary metabolites
pol01230  Biosynthesis of amino acids
pol04980  Cobalamin transport and metabolism
pol04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:pol00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Bpro_0174
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Bpro_0174
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Bpro_0174
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Bpro_0174
   04980 Cobalamin transport and metabolism
    Bpro_0174
Enzymes [BR:pol01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Bpro_0174
SSDB
Motif
Pfam: Met_synt_B12 Pterin_bind B12-binding_2 B12-binding Aldedh
Other DBs
NCBI-ProteinID: ABE42139
UniProt: Q12H53
LinkDB
Position
188631..191465
AA seq 944 aa
MSEIQDPIAVPPMKLSGLEPVAIGEGTLFVNIGERTNVTGSKAFARMILNGEYEQALAVA
RQQVENGAQIIDINMDEAMLDSQAAMVRFLNLIAGEPDIARVPIMIDSSKWSVIEAGLRC
IQGKGIVNSISMKEGVEPFKHQAKLLKRYGAAAVVMAFDEQGQADTYQRKIEICERAYRV
LVDEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFINATRWIKANLPGAKVSGGVSNVSF
SFRGNDPVREAIHTVFLYHAIQAGMDMGIVNAGMVGVYDDLEPTLRERVEDVVLNRQPVY
KPGEPELTPSERLIEVAESAKSGARDDSKKNEWRALPVRERLSHALVLGMNEFITEDTEE
MWQAIKAEGGRPLHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLLPYIE
AEKLLLEAAGGDVKTKGKIIIATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEIL
ARAKVEGADIVGLSGLITPSLEEMQYVASEMQKDEHFRIKKIPLLIGGATTSRVHTAVKI
SPHYEGPVVYVPDASRSVSVAQSLLSDQAARYIDELKADYEKVRTQHANKKQVPMWPLAK
ARANKTPLDWTSYTPPVPKFIGRRVFKNFDLAELARHIDWGPFFQTWDLAGPFPAILKDE
VVGTEAVRVYADAQRLLKRLIEGRWLTASGVIGLYPANSVGDDIEIYTDETRSEVAMTWY
GLRQQAEKTAVPGDDGKNHMRPSRCLSDFVAPKVLPAEARAVRAGHAGQEGHNTFMLPDY
IGLFAVTAGIGAEKKEKYFLDDNDDYSSIMLKALADRLAEAFAEAMHLRVRKDLWGYAAG
ESLTTEELIAEKYQGIRPAPGYPACPDHSVKKDMFALLKADEIGMALTESLAMTPAASVS
GFYLSHPESTYFNVGKIGDDQLQDLARRRGAKAEELQRLLAPNL
NT seq 2835 nt   +upstreamnt  +downstreamnt
atgtccgaaattcaagatcccatcgctgttccccccatgaagctgtccggcctggagccg
gtggccatcggggagggcacgctcttcgtcaacatcggcgagcgcaccaacgtcaccggt
tccaaggcctttgcccgcatgattttgaacggcgagtacgagcaggccctggccgtggcg
cgccagcaggtggagaacggcgcgcaaatcatcgacatcaacatggatgaggccatgctg
gacagccaagccgccatggtgcgctttctgaacctgatcgccggcgaacccgacattgcc
cgcgtgcccatcatgatcgacagctccaaatggagcgtgatcgaggccggcctgcgctgc
atccagggcaagggcatcgtcaactcgatttccatgaaggagggggtcgagcccttcaag
caccaggccaagctgctcaagcgctatggcgcggctgccgtggtgatggcctttgacgag
cagggccaggccgacacctaccagcgcaagatcgagatctgcgagcgggcctaccgcgtg
ctggtcgacgaggtcggctttccgcccgaagacatcatctttgaccccaacatctttgcc
attgccaccggcattgaagaacacaacaactacgcggtcgatttcatcaacgccacacgc
tggatcaaggccaacctgccgggtgccaaggtgtcgggtggtgtgtccaacgtgagtttc
agcttccgtggtaacgacccggtgcgcgaagcgattcacacggtattcctgtaccacgcg
atccaggccggcatggacatgggcatcgtcaacgccggcatggtgggcgtgtatgacgac
ctggagccgacgctgcgcgagcgcgtcgaagacgtggtgctcaatcgccagccggtctac
aagccgggtgagcctgaactcacacccagcgagcgcctgattgaagtggccgaaagcgcc
aaaagcggtgccagggacgacagcaagaaaaacgagtggcgagcgctgccggtgcgcgag
cgtctgtcgcacgcgctggtgctgggcatgaacgaattcatcaccgaagacaccgaggaa
atgtggcaggccatcaaggccgaaggcggccggccgctgcatgtgatcgaaggcccgttg
atggacggcatgaacgtggtgggcgacctgtttggccagggcaagatgtttttgccgcag
gtggtcaaaagcgcccgcgtgatgaagcaggccgtggcgcacctgctgccctacatcgag
gccgaaaagctgctgctcgaagccgcgggcggcgacgtcaagaccaagggcaagatcatc
attgccaccgtcaagggcgatgtgcacgacattggcaagaacatcgtgaccgtcgttctt
cagtgcaacaattttgaggtggtcaacatgggcgtgatggtgccctgccacgaaatcctg
gcgcgcgccaaggtcgaaggcgccgacatcgtcggcctgtcgggcctgatcacgccgagc
ctggaagagatgcagtacgtagcaagcgagatgcagaaggacgagcatttccgcatcaag
aaaatcccgctgctgattggcggcgccaccaccagccgggtgcacacggcggtgaagatt
tccccccattacgagggcccggtggtctatgtgcccgatgcctcgcgcagcgtgagcgtg
gcgcagagcctgctgtccgaccaagccgccagatacattgatgagctgaaggcggactac
gagaaggtgcgcacccagcacgccaacaagaagcaggtgccgatgtggccgctggccaag
gcgcgtgccaacaaaacgcccctcgactggacaagctacacgccgcccgtgcccaaattt
atcggccgccgcgtgtttaaaaacttcgacctggccgagctggcccggcacatcgactgg
ggcccgtttttccagacctgggacctggcgggcccgttcccggccatcctgaaagacgag
gtggtgggcaccgaggccgtgcgtgtgtatgccgacgcacagcgcctgctcaagcgcctg
atcgaaggccgctggctcaccgccagcggggtgatcggcctgtaccctgccaacagcgtg
ggcgacgacatcgagatctacaccgacgagacccgcagcgaggtggccatgacctggtat
ggcctgcgccagcaagccgagaagacggcggtacctggcgacgacggaaagaaccacatg
cgccccagccgctgcctctcggactttgtggcgcccaaggtgcttcccgccgaagccagg
gccgtgcgcgccggccacgccggccaggaaggccacaacacgttcatgctgccggattac
atcggtttgttcgcagtcaccgctggcattggcgccgagaagaaagaaaagtactttctt
gacgacaacgacgactactcgtccatcatgctcaaggcgttggccgaccggctggccgaa
gcctttgccgaggccatgcacctgcgcgtgcgcaaggacctctggggctacgccgctggc
gagtcgctcaccaccgaagagctgattgcagagaaataccagggcatacgccccgcgccc
ggctacccggcctgcccggaccacagcgtgaagaaagacatgtttgcgctgctgaaggcc
gacgagatcgggatggccctgaccgaaagcctggccatgacgccggcggccagtgtcagc
ggtttttacctgagccatcccgagagcacgtatttcaacgtgggcaagatcggcgacgac
cagctgcaggatctggcccggcggcgcggtgcaaaagcggaagagttgcaacgcttgctg
gcgcccaatttgtga

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