| Entry |
|
|---|
| Symbol |
UGT1A3
|
|---|
| Name |
(RefSeq) UDP-glucuronosyltransferase 1-3 precursor
|
|---|
| KO |
|
|---|
| Organism |
pon Pongo abelii (Sumatran orangutan)
|
|---|
| Pathway |
| pon00040 | Pentose and glucuronate interconversions |
| pon00053 | Ascorbate and aldarate metabolism |
| pon00980 | Metabolism of xenobiotics by cytochrome P450 |
| pon00982 | Drug metabolism - cytochrome P450 |
| pon00983 | Drug metabolism - other enzymes |
| pon05204 | Chemical carcinogenesis - DNA adducts |
| pon05207 | Chemical carcinogenesis - receptor activation |
|
|---|
| Module |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:pon00001]
09100 Metabolism
09101 Carbohydrate metabolism
00040 Pentose and glucuronate interconversions
100172533 (UGT1A3)
00053 Ascorbate and aldarate metabolism
100172533 (UGT1A3)
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100172533 (UGT1A3)
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
100172533 (UGT1A3)
00860 Porphyrin metabolism
100172533 (UGT1A3)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
100172533 (UGT1A3)
00982 Drug metabolism - cytochrome P450
100172533 (UGT1A3)
00983 Drug metabolism - other enzymes
100172533 (UGT1A3)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
100172533 (UGT1A3)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
100172533 (UGT1A3)
05207 Chemical carcinogenesis - receptor activation
100172533 (UGT1A3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:pon01003]
100172533 (UGT1A3)
Enzymes [BR:pon01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.17 glucuronosyltransferase
100172533 (UGT1A3)
Glycosyltransferases [BR:pon01003]
Others
Hydrophobic molecule
100172533 (UGT1A3)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
11:137206667..137295834
|
|---|
| AA seq |
534 aa
MATGLQVPLSWLATGLLLLLSVQSWAESGKVLVVPTDGSHWLSMREVVRELYARGHQAVV
LTPEVNMHIKEENFFTLTTYAIPWTQEEFDRVVLGHTQWFFETEHLLKRYSRSMAIMNNI
SLVLHRSCVELLHNEALIRHLNATSFDVVLTDPIYLCGVVLAKYLSIPTVFFLRNIPCDL
DFKGTQCPNPYSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
HGIVIFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
LLGHPMTRAFITHAGSHGIYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
SEDLENALKAVINDKSYKENIIRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCFGKKGRVKKAHKSKTH |
|---|
| NT seq |
1605 nt +upstreamnt +downstreamnt
atggccacaggactccaggttcccctgtcgtggctggccacaggactgctgctcctcctc
agtgtccagtcctgggctgagagtggaaaggtgctggtggtgcccactgatggcagccac
tggctcagcatgcgggaggtcgtgcgggagctctatgccagaggccaccaggcggtggtc
ctcaccccggaggtgaatatgcacatcaaagaagagaactttttcacactgacaacctat
gccattccatggacccaggaggaatttgatcgcgttgtgctgggccacactcaatggttc
tttgaaacagaacatcttctgaagagatattctagaagtatggcaattatgaacaatata
tctttggtccttcataggtcttgtgtggagctactgcataatgaggccctgatcaggcac
ctgaatgctacttcctttgacgtagttttaacagaccccatttacctctgcggggtggtg
ctggctaagtacctgtcgattcctactgtgttttttttgaggaacattccatgtgactta
gactttaagggcacacagtgtccaaatccttactcctatattcctaagttactaacgacc
aattcagaccacatgacattcctgcaaagggtcaagaacatgctctaccctctggccctg
tcctacctttgccatgctgtttctgctccttatgcaagccttgcctctgagctttttcag
agagaggtgtcagtggtggatcttgtcagccatgcatctgtgtggctgttccgaggggac
tttgtgatggactaccccaggccaatcatgcccaacatggtcttcattgggggcatcaac
tgtgccaacaggaagccactatctcaggaatttgaagcctacattaatgcttctggagaa
catggaattgtgattttctctttgggatcaatggtctcagaaattccagagaagaaagcc
atggcaattgctgatgctttgggcaaaatccctcagacagtcctgtggcggtacactgga
acccgaccatcgaatcttgcgaacaacacgatacttgttaagtggctaccccaaaacgat
ctgcttggtcacccgatgacccgtgcctttatcacccatgctggttcccatggtatttat
gaaagcatatgcaatggcgttcccatggtgatgatgcccttgtttggtgatcagatggac
aatgcaaagcgcatggagactaagggagctggagtgaccctgaatgttctggaaatgact
tctgaagatttagaaaatgctctaaaagcagtcatcaatgacaaaagctacaaggaaaac
atcatacgcctctccagccttcacaaggaccgcccggtggagccgctggacctggctgtg
ttctgggtggagtttgtgatgaggcacaagggcgcgccacacctgcgccctgcagcccac
gacctcacctggtaccagtaccattccttggacgtgatcggtttcctcctggccgttgtg
ctgacagtggccttcatcacctttaaatgttgtgcttatggctaccggaaatgcttcggg
aaaaaagggcgagttaagaaagcccacaaatccaagacccattga |
|---|
