Pongo abelii (Sumatran orangutan): 100433988 Help Entry 100433988         CDS       T01416                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04062   Chemokine signaling pathway pon04151   PI3K-Akt signaling pathway pon04217   Necroptosis pon04550   Signaling pathways regulating pluripotency of stem cells pon04630   JAK-STAT signaling pathway pon04658   Th1 and Th2 cell differentiation pon04659   Th17 cell differentiation pon05161   Hepatitis B pon05162   Measles pon05166   Human T-cell leukemia virus 1 infection pon05169   Epstein-Barr virus infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05223   Non-small cell lung cancer pon05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100433988 (JAK3)    04151 PI3K-Akt signaling pathway     100433988 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100433988 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     100433988 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     100433988 (JAK3)    04659 Th17 cell differentiation     100433988 (JAK3)    04062 Chemokine signaling pathway     100433988 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100433988 (JAK3)    05203 Viral carcinogenesis     100433988 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     100433988 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100433988 (JAK3)    05161 Hepatitis B     100433988 (JAK3)    05162 Measles     100433988 (JAK3)    05169 Epstein-Barr virus infection     100433988 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     100433988 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pon01001]     100433988 (JAK3) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100433988 (JAK3) Protein kinases [BR:pon01001]  Non-receptor tyrosine kinases   JAK family [OT]    100433988 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl FERM_C_FAK1 Kinase-like ABC1 Kdo SH2 LRR_RI_capping Haspin_kinase Motif Other DBs NCBI-GeneID:  100433988 NCBI-ProteinID:  XP_024092214 Ensembl:  ENSPPYG00000009724 LinkDB All DBs Position 20:complement(18050248..18073335) Genome browser AA seq 1167 aa AA seqDB search MTVAQETKGPTQEGAEWDFPLAASQLCPPFEGPGSLPARQVALMAPPSEETPLIPQRSCS LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED LSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGLRKDLASAILDLPVLEHL FAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQSQRPGELLKTISYKACLPPS LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVG LPGALGGQDGLGLLRVAGDSGISWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRL VTLTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCH GPITLDFAINKLKTGGSHPGSYVLRRSPQDFDSFLLTVCVQTPLGPDYKGCLIRRSPTGT FLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTS SLVQPQSQYQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEVVDGEARKTEVLLKV MDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGH LVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPA VLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFSGVTMPISALDPAKKLQF YEDQQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALA PRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLD KDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRM MGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQLDM LWSGSRGCETHAFTAHPEGKPHSLSFL NT seq 3504 nt NT seq  +upstreamnt  +downstreamnt atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct ctcgctgcctcccagctctgccctcccttcgaaggcccagggtccctgcccgctaggcaa gttgcactcatggcacctccaagtgaagagacgcccctgatccctcagcgttcatgcagc ctcttgtccacggaggctggtgccctgcatgtgctgctgcccgctcggggccccgggccc ccccagcgcctatctttctcctttggggaccacttggctgaggacctgtgcgtgcaggct gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggac ctgtcctgctggttccccccgagccacatcttttcagtggaggatgccagcacccaagtc ctgctctacaggattcgcttttacttccccaattggtttgggctggagaagtgccaccgc tttgggctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctc tttgcccagcaccgcagtgacctggtgagtgggcgcctccccgtgggcctcagtctcaaa gagcagggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcag tcccagcggccgggagagctgctgaagactatcagctacaaggcctgcctacccccaagc ctgcgcgacctgatccagggcctgagcttcgtgacgcggaggcgtattcggaggacggtg cgcagggccctgcgccgcgtggccgcctgccaggcagaccggcactcgctcatggccaag tacatcatggacctggagcggctggatccagccggggccgccgagaccttccacgtgggc ctccctggggcccttggtggccaggacgggctggggctgctccgcgtggctggggacagc ggcatctcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaa atcgtagacattagcatcaagcaggccccgcgcgttggcccggccggggagcaccgcctg gtcactcttaccaggacagacaaccagattttggaggccgagttcccagggctgcccgag gctctgtcgttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcac ttcttctgcaaggaggtggcaccgccgaggctgctggaggaagtggccgagcagtgccac ggccccatcactctggactttgccatcaacaagcttaagactgggggctcacatcctggc tcctatgttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgtc cagaccccccttggtcctgattataagggctgcctcatccggcgcagccccacaggaacc ttccttctggttggcctcagccgaccccacagcagtcttcgagagctcctggcaacgtgc tgggatggggggctgcacgtagatggggtggcagtgaccctcacctcctgctgtatcccc agacccaaagaaaagtccaacctgatcgtggtccagagaggtcacagcccacccacatca tccttggttcagccccaatcccaataccagctgagtcagatgacatttcacaagatccct gctgacagcctggagtggcatgagaacctgggccatgggtccttcaccaagatttaccgg ggctgtcgccatgaggtggtggatggggaggcccgaaagacagaggtgctgctgaaggtg atggatgctaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagc caagtgtcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcacc atggtgcaggaatttgtacacctgggggcgatagacatgtatcttcgaaaacgtggccac ctggtgccagccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactat ctggaggacaaaggcctcccccatggcaatgtctctgcccggaaggtgctcctggctcgg gagggggctgatgggagcccgcccttcatcaagctgagtgaccctggggtcagccccgct gtgttaagcctggagatgctcactgacaggatcccctgggtggcccccgagtgtctccgg gaggcccagacacttagcttggaagctgacaagtggggcttcggcgccacggtctgggaa gtgtttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattt tatgaggaccagcagcagctgccggcccccaagtggacagagctggccctgctgattcaa cagtgcatggcctatgagccagtccagaggccctccttccgagccgtcattcgtgaccta aatagcctcatctcttcagactatgagctcctctcagaccccacacctggagccctggca cctcgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttt gaggagagacacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggag ctgtgccgctatgacccgctaggtgacaatacaggtgccctggtggccgtgaaacagctg cagcacagcgggccagaccagcagagggactttcagcgggagattcagatcctcaaagca ctgcacagtgatttcattgtcaagtatcgtggtgtcagctacggcccgggccgccagagc ctgcggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcac cgtgcgcgcctcgatgccagccgcctccttctctattcctcacagatctgcaagggcatg gagtacctaggctcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctcgtg gagagcgaggcacacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgac aaagactactacgtcgtccgcgagccgggccagagccccattttctggtatgcccccgaa tccctctcggacaatatcttctctcgccagtcagacgtctggagcttcggggtcgtcctg tacgagctcttcacctactgcgacaaaagctgcagtccctcggccgagttcctgcggatg atgggatgtgagcgggatgtccccgccctctgccgcctcctggaactgctggaggagggc cagaggctgccggcgcctcctgcctgccctgcagaggttcacgagctcatgaagctgtgc tgggcccctagcccacaggaccggccatcattcagcaccctgggcccccagctggacatg ctgtggagcggaagccgggggtgtgagactcatgccttcactgctcacccagagggcaaa ccccactccctgtcctttttatag

DBGET integrated database retrieval system