Pongo abelii (Sumatran orangutan): 100435170
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Entry
100435170 CDS
T01416
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00590
Arachidonic acid metabolism
pon01100
Metabolic pathways
pon01523
Antifolate resistance
pon04726
Serotonergic synapse
pon04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
100435170 (ALOX12)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100435170 (ALOX12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100435170 (ALOX12)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100435170 (ALOX12)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
100435170 (ALOX12)
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
100435170
NCBI-ProteinID:
XP_024090401
Ensembl:
ENSPPYG00000007882
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All DBs
Position
19:6842158..6857713
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AA seq
782 aa
AA seq
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MFAPTRGLRPTSIPPSWEVQEGPAAPTPLASPWLGPLYHPAATLRPGGTASPRSRLYRSA
RRFGLVWGGDLGAPKTCEEGGAADRSFKGWNWPQGAGSPGRSRESRRTRLPSPKLLGGAM
GRYRIRVATGAWLFSGSYNRVQLWLVGARGEAELELQLRPARGEEEEFDHDVAEDLGLLQ
FVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTACLPGDNAL
DVFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKAG
ALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFGYQFLNGANPMLL
RRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEVDFILLDGIPANVIRGEKQYLAAPLV
MLKMEPNGKLLPMVIQIQPPNPSSPTPTLFLPSDPPLVWLLAKSWVRNSDFQLHEIQYHL
LNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTG
GGGHVQLLRRVAAQLTYCSLCPPDDLADRGLLGLPGALYARDALRLWEIIARYVEGIVHL
FYQRDDVVKGDPELQAWCREITEVGLCQAQDRGFPVSFHSQSQLCHFLTMCVFTCTAQHA
AINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQ
PDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEQEITARNEQLDWPYEYLKPSCIENSV
TI
NT seq
2349 nt
NT seq
+upstream
nt +downstream
nt
atgttcgctccaacccgggggctcaggcccacctcgatcccgccttcctgggaggtccag
gaaggccccgccgcacccaccccgttggcctcaccctggctcgggcccctttatcatcct
gcagctacgctccgaccaggaggcacagccagtccccgcagccggctctaccgctctgct
cgcaggtttgggctagtctggggcggggacttgggagcgcctaaaacttgcgaggagggc
ggggccgcagaccggtcctttaaaggttggaactggccccaaggcgccggcagccctggg
cggtcccgggaatcgcgcaggacccggctcccctcgcctaagctgctggggggcgccatg
ggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgtacaatcgc
gtgcagctttggctggtcggggcgcgcggggaggcggagctggagctgcagctgcggccg
gcgcggggcgaggaggaggagtttgatcatgacgttgcagaggacttggggctcctgcag
ttcgtgaggctgcgcaaacaccactggctggtggacgacgcgtggttctgcgaccgcatc
acggtgcagggccctggagcctgcgcggaggtggccttcccgtgctaccgctgggtgcag
ggcgaggacatcctgagcctgcccgagggcaccgcctgcctgccaggagacaatgctttg
gacgtgttccagaagcatcgagagaaggaactgaaagacagacagcagatctactgctgg
gccacctggaaggaagggttacccctgaccatcgctgcagaccgtaaggatgatctacct
ccaaatatgagattccatgaggagaagaggctggactttgaatggacactgaaggcaggg
gctctggagatggccctcaaacgtgtttacaccctcctgagctcctggaactgcctagaa
gactttgatcagatcttctggggccagaagagtgccctggctgagaaggttcgccagtgc
tggcaggatgatgagctgttcggctaccagttcctcaatggtgccaaccccatgctgttg
agacgctcgacctctctgccctccaggctagtgctgccctcggggatggaagagcttcag
gctcaactggagaaagaacttcagaatggttccctgtttgaagttgacttcatccttctg
gatggaattccagccaacgtgatccgaggagagaagcagtacctggctgcccccctcgtc
atgctgaagatggagcccaatgggaagctgctgcccatggtcatccagattcagcctccc
aaccccagctctccaaccccaacactgttcctgccttcagaccccccacttgtctggctc
ctggcaaagtcctgggtccgaaattcagatttccaactgcacgagatccagtatcacttg
ctcaacactcacctggtggctgaggtcatcgctgtcgccaccatgcggtgcctcccagga
ctgcaccccatcttcaagttcctgatcccccatatccgctacaccatggaaatcaacacc
cgggcccggacccaactcatctcagatggaggaatttttgataaggcagtgagcacaggt
ggagggggccatgtgcagttgctccgtcgggtggcggctcagctgacctactgctccctc
tgtcctcctgacgacctggctgaccggggcctgctgggactcccaggtgctctctatgcc
cgtgatgctttacggctctgggagatcattgccaggtatgtggaggggattgtccacctc
ttctaccaaagggatgatgtagtgaagggggaccctgagctgcaggcctggtgtcgggag
atcacggaggtggggctgtgccaggcccaggaccgaggtttccctgtctccttccactcc
cagagtcaactctgccatttcctcaccatgtgcgtcttcacgtgcactgcccagcatgcc
gccatcaaccagggccagctggactggtatgcctgggtccctaatgccccatgcacaatg
cggatgcccccacccaccaccaaggaagatgtgacgatggccacagtgatggggtcacta
cctgatgtccggcaggcctgtcttcaaatggccatctcatggcatctgagtcgccgccag
ccagacatggtgcctctggggcatcacaaagaaaaatatttctcaggccccaagcccaaa
gctgtgctaaaccaattccgaacagatttggaaaagctggaacaggagattacagcccgg
aatgagcaacttgactggccctatgaatatctgaagcccagctgcatagagaacagtgtc
accatctga
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