Pongo abelii (Sumatran orangutan): 100440983
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Entry
100440983 CDS
T01416
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04014
Ras signaling pathway
pon04072
Phospholipase D signaling pathway
pon04148
Efferocytosis
pon04360
Axon guidance
pon04625
C-type lectin receptor signaling pathway
pon04630
JAK-STAT signaling pathway
pon04650
Natural killer cell mediated cytotoxicity
pon04660
T cell receptor signaling pathway
pon04670
Leukocyte transendothelial migration
pon04722
Neurotrophin signaling pathway
pon04920
Adipocytokine signaling pathway
pon04931
Insulin resistance
pon05168
Herpes simplex virus 1 infection
pon05205
Proteoglycans in cancer
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05211
Renal cell carcinoma
pon05220
Chronic myeloid leukemia
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100440983 (PTPN11)
04630 JAK-STAT signaling pathway
100440983 (PTPN11)
04072 Phospholipase D signaling pathway
100440983 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100440983 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
100440983 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
100440983 (PTPN11)
04660 T cell receptor signaling pathway
100440983 (PTPN11)
04670 Leukocyte transendothelial migration
100440983 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100440983 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100440983 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100440983 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100440983 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100440983 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100440983 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100440983 (PTPN11)
05211 Renal cell carcinoma
100440983 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
100440983 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100440983 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pon01009
]
100440983 (PTPN11)
Enzymes [BR:
pon01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100440983 (PTPN11)
Protein phosphatases and associated proteins [BR:
pon01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100440983 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100440983
NCBI-ProteinID:
XP_009246546
Ensembl:
ENSPPYG00000004976
UniProt:
H2NIQ5
LinkDB
All DBs
Position
10:111230252..111326717
Genome browser
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggtgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcctagtaaaagtaaccctggagac
ttcacactttccgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtatggaggggagaaatttgccactttggctgagttggtccagtat
tacatggaacatcacgggcaattaaaagagaagaatggagatgtcattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattaactgaaaaaggaaaacatggtagttttcttgtacgagagagc
cagagccaccctggagattttgttctttctgtgcgcactggtgatgacaaaggggagagc
aatgacggcaagtctaaagtgacccatgttatgattcgctgtcaggaactgaaatacgac
gttggtggaggagaacggtttgattctttgacagatcttgtggaacattataagaagaat
cctatggtggaaacattgggtacagttctacaactgaagcagccccttaacacgactcgt
ataaatgctgctgaaatagaaagcagagttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcaaaggcaagaaaacaaaaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaacgac
ttttggcggatggtgttccaagaaaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgctctaaaagaatat
ggcgtcatgcgtgttaggaacgtcaaagaaagtgccgctcatgactatacgctaagagaa
cttaaactttcaaaggttggacaagctctactccaggggaatacggagagaacggtctgg
caataccactttcggacctggccggaccacggagtgcccagcgaccccgggggcgtgctg
gacttcctggaggaggtgcaccataagcaggagagcatcatggatgcagggccggtcgtg
gtgcactgcagtgctggaattggccggacagggacgttcattgtgattgatattcttatt
gacatcatcagagagaaaggtgttgactgcgacattgatgttcccaaaaccatccagatg
gtgcggtctcagaggtcagggatggtccagacagaagcacagtaccgatttatctatatg
gcggtccagcattatattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcacgaatatacaaatattaagtattctctagcggaccagacgagtggagat
cagagccccctcccgccttgtactccaacgccaccctgtgcagaaatgagagaagacagt
gctagagtctatgaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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