Pongo abelii (Sumatran orangutan): 100442682
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Entry
100442682 CDS
T01416
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04020
Calcium signaling pathway
pon04151
PI3K-Akt signaling pathway
pon05200
Pathways in cancer
pon05216
Thyroid cancer
pon05223
Non-small cell lung cancer
pon05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100442682 (RET)
04020 Calcium signaling pathway
100442682 (RET)
04151 PI3K-Akt signaling pathway
100442682 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100442682 (RET)
05230 Central carbon metabolism in cancer
100442682 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
100442682 (RET)
05223 Non-small cell lung cancer
100442682 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100442682 (RET)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100442682 (RET)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
RET family
100442682 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD3
RET_CLD4
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
100442682
NCBI-ProteinID:
XP_002820699
Ensembl:
ENSPPYG00000002208
UniProt:
H2NA70
LinkDB
All DBs
Position
8:49195025..49249441
Genome browser
AA seq
1116 aa
AA seq
DB search
MAKATSGAAGLRLLLLLLLLLLLLGKVALGLYFSRDAYWEKLYVDQPAGTPLLYVHALRD
TPEEVPSFHLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHNSWEKLSVRNRGFPL
LTVYLKVFLSPTSLRESECQWPGCARVYFSFFNTSFPACSSLKPQELCFPETRPSFRIRE
NRPPGTFHQFRLLPVQYLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYE
LVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRV
FDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVL
NRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARR
FAQIGKVCVENCQVFSGINVQYELHSSGANCSMLGVVTSAEDTSGILFVNDTKALRRPKC
AELHYMVVATDQQTSRQAQAQLLVTVEGSHVAEEAGCPLSCAVSKRRPECEECGGLGSPT
GRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGE
PRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIH
RYHKFAHKPPIPSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKWE
FPRKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASPSELRDLLSEFNL
LKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSL
DHPDERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRD
VYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPE
RLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDL
AASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLT
RADGTNTGFPRYANDSVYANWMLSPSAAKLMDTFDS
NT seq
3351 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacgtccggtgccgcggggctgcggctgctgttgctgctgctgctgctg
ctgctgctgctaggcaaagtggcattgggcctctacttctcgagggatgcttactgggag
aagctgtatgtggaccagccggccggcacacccttgctgtacgtccatgccctgcgggac
acccctgaggaggtgcccagcttccacctgggccagcatctctacggcacgtaccgcaca
cggctgcatgagaacaactggatctgcatccaggaggacaccggcctcctctaccttaac
cggagcctggaccacaactcctgggagaagctcagtgtccgcaaccgcggctttcccctg
ctcaccgtctacctcaaggtcttcctgtcacccacatcccttcgtgagagcgagtgccag
tggccaggctgtgcccgcgtgtacttctccttcttcaacacctcctttccagcctgcagc
tccctcaagccccaggagctctgcttcccagagacaaggccctccttccgcattcgggag
aaccgacccccaggcaccttccaccagtttcgcctgctgcctgtacagtacttgtgcccc
aacatcagcgtggcctacaggctcctggagggtgagggtctgcccttccgctgcgccccg
gacagcctggaggtgagcacacgctgggccctggaccgcgagcagcgggagaagtacgag
ctggtggccgtgtgcaccgtgcacgccggcgcgcgcgaggaggtggtgatggtgcccttc
ccggtgaccgtgtacgacgaggacgactcggcgcccaccttccccgcgggcgtcgacacc
gccagcgccgtggtggagttcaagcggaaggaggacaccgtggtggccacgctgcgtgtc
ttcgatgcagacgtggtacctgcatcaggggagctggtgaggcggtacacaagcacgctg
ctccccggggacacctgggcccagcagaccttccgggtggagcactggcccaacgagacc
tcggtccaggccaacggcagcttcgtgcgggcgaccgtacatgactataggctggttctc
aaccggaacctctccatctcggagaaccgcaccatgcagctggccgtgctggtcaatgac
tcggacttccagggcccaggagcgggtgtcctcttgctccacttcaacgtgtcggtgctg
ccggtcagcctgcacctgcccagtacctactccctctccgtgagcaggagggctcgccga
tttgcccagatcgggaaagtctgtgtggaaaactgccaggtgttcagtggcatcaacgtc
cagtatgagctgcattcctccggcgccaactgcagcatgctaggggtggtgacctcagcc
gaagacacctcggggatcctgtttgtgaatgacaccaaggccctgcggcggcccaagtgt
gccgaacttcactacatggtggtggccaccgaccagcagacctccagacaggcccaggcc
cagctgcttgtaacggtggaggggtcacatgtggccgaggaggcgggctgccccctgtcc
tgtgcagtcagcaagagacggccggagtgtgaggagtgtggcggcctgggctccccaaca
ggcagatgtgagtggaggcaaggagatggcaaagggatcaccaggaacttctccacctgc
tctcccagcaccaagacctgccccgacggccactgcgatgttgtggagacccaagacatc
aacatttgccctcaggactgcctccggggcagcattgtcgggggccacgagcccggggag
ccccggggaattaaagctggctatggcacttgcaactgcttccctgaggaagagaagtgc
ttctgcgagcccgaagacatccaggatccactgtgcgacgagctgtgccgcacggtgatc
gcggccgccgtcctcttctccttcatcgtctcggtgctgctgtctgccttctgcatccac
cgctaccacaagtttgcccacaagccacccatcccctcagctgagatgaccttccggagg
cccgcccaggccttcccggtcagctactcctcttccggtgcccgccgaccctcactggac
tccatggagaaccaggtctccgtggatgccttcaagatcccggaggatccaaagtgggaa
ttccctcggaagaacttggttcttggaaaaactctaggagaaggcgaatttggaaaagtg
gtcaaggcaacggccttccgtctgaaaggcagagcagggtacaccacggtggccgtgaag
atgctgaaagagaacgcctccccgagtgagctgcgagacctgctgtcagagttcaacctc
ctgaagcaggtcaaccacccacatgtcatcaaattgtatggggcctgcagccaggatggc
ccgctcctcctcatcgtggagtacgccaaatacggctccctgcggggcttcctccgcgag
agccgcaaagtggggcctggctacctgggcagcggaggcagccgcaactccagctccctg
gaccacccggacgagcgggccctcaccatgggcgacctcatctcatttgcctggcagatc
tcacgggggatgcagtatctggccgagatgaagctcgttcatcgggacttggcagccaga
aacatcctggtagctgaggggcggaagatgaagatttcggatttcggcttgtcccgagat
gtttatgaagaggattcctacgtgaagaggagcaagggtcggattccagttaaatggatg
gcaattgagtccctttttgatcatatctacaccacccaaagtgatgtatggtcttttggt
gtcctgctgtgggagatcgtgaccctagggggaaacccctatcctgggattcctcctgag
cggctcttcaaccttctgaagaccggccaccggatggagaggccagacaactgcagcgag
gagatgtaccgcctgatgctgcaatgctggaagcaggagccggacaaaaggccagtgttt
gcagacatcagcaaagacctggagaagatgatggttaagagcagagactacttggacctt
gcggcgtccactccgtctgactccctgctttatgacgacggcctctcagaggaggagaca
ccgctggtggactgtaataatgcccccctccctcgagccctcccttccacatggattgaa
aacaaactctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacg
agagctgatggcactaacactgggtttccaagatatgcaaatgatagtgtatatgctaac
tggatgctttcaccctcagcggcaaaattaatggacacgtttgatagttaa
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