Pongo abelii (Sumatran orangutan): 100442751
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Entry
100442751 CDS
T01416
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X2
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04120
Ubiquitin mediated proteolysis
pon04144
Endocytosis
pon04330
Notch signaling pathway
pon04668
TNF signaling pathway
pon04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100442751 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100442751 (ITCH)
04668 TNF signaling pathway
100442751 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100442751 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100442751 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pon04131
]
100442751 (ITCH)
04121 Ubiquitin system [BR:
pon04121
]
100442751 (ITCH)
Enzymes [BR:
pon01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100442751 (ITCH)
Membrane trafficking [BR:
pon04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100442751 (ITCH)
Ubiquitin system [BR:
pon04121
]
Ubiquitin ligases (E3)
HECT type E3
100442751 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100442751
NCBI-ProteinID:
XP_024094634
Ensembl:
ENSPPYG00000010936
LinkDB
All DBs
Position
21:38525400..38681494
Genome browser
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQSLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNGS
DDPEDAGAGENRRVSGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGR
VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNKRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHFTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctcaccatgaaatcacagctt
cagatcactgtcatctcagcaaaacttaaggaaaataagaagaattggtttggaccaagt
ccttacgtagaggtcacagtagatggacagtcaaagaagacagaaaaatgcaacaacacg
aacagtcccaagtggaagcaatcccttacagttattgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaagaagtagttgtgactttg
cagcttggaggtgacaaagagccaacagagacaataggagacttgtcaatttgtcttgat
gggctacagttagagtctgaagttgttaccaatggtgaaactacatgttcagaaagtgct
tctcagaatgatgatggctccagatccaaggatgaaacaagagtgagcacaaatggatca
gatgaccccgaagatgcaggagctggtgaaaataggagagtcagtgggaataattctcca
tcactctcaaatggcggttttaaaccttctagacctccaagaccttcacgaccaccacca
cccaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
gggtctagtacaggctctctgccgccgacaaatacaaatacaaatacatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtaactcaagctcccttgccacctggttgggagcagagagtggaccagcacgggcga
gtttactatgtagatcatgttgagaaaagaacaacatgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatccgtccggaactatgaacaatggcag
ctacagcgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttatttgctacatcacaaagtaaagaatttgatcctcttggtccattgcca
cctggatgggagaagagaacagacagcaatggcagagtatatttcgtcaaccacaacaca
cgaattacgcaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattccatattttgtggaccacaataaa
agaactaccacctatatagatccccgcacaggaaaatctgccctagacaatggacctcag
atagcctatgttcgggacttcaaagcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcaacagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcagatttattgccatggctctgttccatgggaaattcatagacacaggtttttcttta
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttataattctctcatctgggttaaggaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgttgacaaagaaattctaggtgaaattaagagtcatgatctgaaa
cctaatggtggcaatattcttgtaacagaagaaaataaagaggagtacatcagaatggta
gctgagtggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcaatatttgcaatactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tttacgaggaccagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagtaggagga
tttgctgatctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggctacccagaagtcatacctgttttaatcgcctggacctgccaccatacaag
agctatgagcaattgaaggaaaagctgttgtttgccatagaagaaacagaaggatttgga
caagagtaa
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