Pongo abelii (Sumatran orangutan): 100453941 Help Entry 100453941         CDS       T01416                                  Symbol IL6 Name (RefSeq) interleukin-6 isoform X2   KO K05405   interleukin 6 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01521   EGFR tyrosine kinase inhibitor resistance pon01523   Antifolate resistance pon04060   Cytokine-cytokine receptor interaction pon04061   Viral protein interaction with cytokine and cytokine receptor pon04066   HIF-1 signaling pathway pon04068   FoxO signaling pathway pon04151   PI3K-Akt signaling pathway pon04218   Cellular senescence pon04620   Toll-like receptor signaling pathway pon04621   NOD-like receptor signaling pathway pon04623   Cytosolic DNA-sensing pathway pon04625   C-type lectin receptor signaling pathway pon04630   JAK-STAT signaling pathway pon04640   Hematopoietic cell lineage pon04657   IL-17 signaling pathway pon04659   Th17 cell differentiation pon04668   TNF signaling pathway pon04672   Intestinal immune network for IgA production pon04931   Insulin resistance pon04932   Non-alcoholic fatty liver disease pon04933   AGE-RAGE signaling pathway in diabetic complications pon04936   Alcoholic liver disease pon05010   Alzheimer disease pon05020   Prion disease pon05022   Pathways of neurodegeneration - multiple diseases pon05132   Salmonella infection pon05133   Pertussis pon05134   Legionellosis pon05135   Yersinia infection pon05142   Chagas disease pon05143   African trypanosomiasis pon05144   Malaria pon05146   Amoebiasis pon05152   Tuberculosis pon05161   Hepatitis B pon05162   Measles pon05163   Human cytomegalovirus infection pon05164   Influenza A pon05166   Human T-cell leukemia virus 1 infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05171   Coronavirus disease - COVID-19 pon05200   Pathways in cancer pon05202   Transcriptional misregulation in cancer pon05321   Inflammatory bowel disease pon05323   Rheumatoid arthritis pon05332   Graft-versus-host disease pon05410   Hypertrophic cardiomyopathy pon05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     100453941 (IL6)    04668 TNF signaling pathway     100453941 (IL6)    04066 HIF-1 signaling pathway     100453941 (IL6)    04068 FoxO signaling pathway     100453941 (IL6)    04151 PI3K-Akt signaling pathway     100453941 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     100453941 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     100453941 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     100453941 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     100453941 (IL6)    04620 Toll-like receptor signaling pathway     100453941 (IL6)    04621 NOD-like receptor signaling pathway     100453941 (IL6)    04623 Cytosolic DNA-sensing pathway     100453941 (IL6)    04625 C-type lectin receptor signaling pathway     100453941 (IL6)    04659 Th17 cell differentiation     100453941 (IL6)    04657 IL-17 signaling pathway     100453941 (IL6)    04672 Intestinal immune network for IgA production     100453941 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100453941 (IL6)    05202 Transcriptional misregulation in cancer     100453941 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100453941 (IL6)    05161 Hepatitis B     100453941 (IL6)    05171 Coronavirus disease - COVID-19     100453941 (IL6)    05164 Influenza A     100453941 (IL6)    05162 Measles     100453941 (IL6)    05168 Herpes simplex virus 1 infection     100453941 (IL6)    05163 Human cytomegalovirus infection     100453941 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     100453941 (IL6)    05169 Epstein-Barr virus infection     100453941 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     100453941 (IL6)    05135 Yersinia infection     100453941 (IL6)    05133 Pertussis     100453941 (IL6)    05134 Legionellosis     100453941 (IL6)    05152 Tuberculosis     100453941 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     100453941 (IL6)    05144 Malaria     100453941 (IL6)    05142 Chagas disease     100453941 (IL6)    05143 African trypanosomiasis     100453941 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     100453941 (IL6)    05321 Inflammatory bowel disease     100453941 (IL6)    05332 Graft-versus-host disease     100453941 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     100453941 (IL6)    05020 Prion disease     100453941 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     100453941 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100453941 (IL6)    05410 Hypertrophic cardiomyopathy     100453941 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100453941 (IL6)    04932 Non-alcoholic fatty liver disease     100453941 (IL6)    04931 Insulin resistance     100453941 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     100453941 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100453941 (IL6)    01523 Antifolate resistance     100453941 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:pon04052]     100453941 (IL6) Cytokines and neuropeptides [BR:pon04052]  Cytokines   Interleukins    100453941 (IL6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL6 IL11 IL23 Phage_int_SAM_1 GCSF Motif Other DBs NCBI-GeneID:  100453941 NCBI-ProteinID:  XP_002818205 Ensembl:  ENSPPYG00000017740 UniProt:  A0A6D2YB13 LinkDB All DBs Position 6:complement(62456002..62461423) Genome browser AA seq 212 aa AA seqDB search MNSVSTSAFGPVAFSLGLLLVLPAALPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM NT seq 639 nt NT seq  +upstreamnt  +downstreamnt atgaactccgtctccacaagcgccttcggtccagttgccttctccctggggctgctcctg gtgttgcctgctgccttacctgccccagtaccaccaggagaagattccaaagatgtagcc gccccacacagacagccactcacctcttcagaacgaattgacaaacaaattcggtacatc ctcgacggcatctcagccctgagaaaggagacttgtaacaagagtaacatgtgtgaaagc agcaaagaggcactggcagaaaacaacctgaaccttccaaagatggctgaaaaagatgga tgcttccaatctggattcaatgaggagacttgcctggtgaaaatcatcactggtcttttg gagtttgaggtatacctagagtacctccagaacaggtttgagagcagtgaggaacaagcc agagctgtgcagatgagtacaaaagtcctgatccagttcctgcagaaaaaggcaaagaat ctagatgcaataactacccctgacccaaccacgaatgccagcctgctgacgaagctgcag gcacagaaccagtggctgcaggacatgacaactcatctcattctgcgcagctttaaggag ttcctgcagtccagcctgagggctcttcggcaaatgtag

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