KEGG   Pongo abelii (Sumatran orangutan): 100460111
Entry
100460111         CDS       T01416                                 
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
  KO
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon00140  Steroid hormone biosynthesis
pon00980  Metabolism of xenobiotics by cytochrome P450
pon01100  Metabolic pathways
pon05204  Chemical carcinogenesis - DNA adducts
Module
pon_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:pon00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100460111 (HSD11B1L)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    100460111 (HSD11B1L)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    100460111 (HSD11B1L)
Enzymes [BR:pon01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146  11beta-hydroxysteroid dehydrogenase
     100460111 (HSD11B1L)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR DUF1776
Other DBs
NCBI-GeneID: 100460111
NCBI-ProteinID: XP_002828544
Ensembl: ENSPPYG00000009430
UniProt: A0A6D2WCB5
LinkDB
Position
20:5593877..5601339
AA seq 287 aa
MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTA
HTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAP
AGTRARSPQATRWLMQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSA
AKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAV
IRGGATRAAGVFYPWRFHLLCLLRRWLPRPRAWFIRQELNVTAAAAA
NT seq 864 nt   +upstreamnt  +downstreamnt
atgaaggtgcttctcctcacagggctgggggccctgttctttgcctattattgggatgac
aacttcgacccagccagcctccagggagcgcgagtgctgctgacaggggccaacgctggt
gttggtgaggagctggcctatcactacgcgcgtctgggctcccacctggtgctcactgcc
cacactgaggctctcctgcagaaggtggtagggaactgccggaagctgggcgcccccaag
gtcttctacatcgcggcggacatggcctcccctgaggcgcccgagagcgtggtgcagttt
gcgctggacaagctgggcgggctggactacctcgtgctgaaccacatcggcggcgccccg
gccggcacgcgagcccgcagcccccaggcaacgcgctggctcatgcaggtaaactttctg
agctacgtgcaactgacgtcgctggcgctgcccagcctgacggacagcaaaggctccctg
gtggtggtgtcctcgctgctcggccgcgtgcccacgtcgttctccactccctactcggcg
gccaagtttgcgctggacggcttcttcggctccctgcggcgggagctggacgtgcaggac
gtgaacgtggccatcaccatgtgcgtcctgggcctccgagaccgcgcctccgccgccgag
gcagtcaggggagtcacgagggtcaaggcggccccggggcccaaggcagccctggccgta
atccgcggcggcgccacgcgcgcggccggcgtcttctacccgtggcgtttccacctgctg
tgcttgctccggcgctggctgccgcgcccgcgggcctggtttatccgccaggagctcaac
gtcacggccgcggctgcagcctga

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