KEGG   Plecotus auritus (brown big-eared bat): 308235401
Entry
308235401         CDS       T11911                                 
Symbol
MMP2, AC0HY7_002234
Name
(RefSeq) 72 kDa type IV collagenase
  KO
K01398  matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
Organism
pots  Plecotus auritus (brown big-eared bat)
Pathway
pots01522  Endocrine resistance
pots04670  Leukocyte transendothelial migration
pots04912  GnRH signaling pathway
pots04915  Estrogen signaling pathway
pots04926  Relaxin signaling pathway
pots04933  AGE-RAGE signaling pathway in diabetic complications
pots05200  Pathways in cancer
pots05205  Proteoglycans in cancer
pots05219  Bladder cancer
pots05415  Diabetic cardiomyopathy
pots05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pots00001]
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    308235401 (MMP2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    308235401 (MMP2)
   04915 Estrogen signaling pathway
    308235401 (MMP2)
   04926 Relaxin signaling pathway
    308235401 (MMP2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    308235401 (MMP2)
   05205 Proteoglycans in cancer
    308235401 (MMP2)
  09162 Cancer: specific types
   05219 Bladder cancer
    308235401 (MMP2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    308235401 (MMP2)
   05415 Diabetic cardiomyopathy
    308235401 (MMP2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    308235401 (MMP2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    308235401 (MMP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pots01002]
    308235401 (MMP2)
Enzymes [BR:pots01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.24  gelatinase A
     308235401 (MMP2)
Peptidases and inhibitors [BR:pots01002]
 Metallo peptidases
  Family M10
   308235401 (MMP2)
SSDB
Motif
Pfam: Peptidase_M10 fn2 Hemopexin PG_binding_1 Reprolysin_3 Reprolysin_5 Peptidase_M66
Other DBs
NCBI-GeneID: 308235401
NCBI-ProteinID: XP_080500293
LinkDB
Position
10:complement(55868831..55893008)
AA seq 661 aa
MMETLVARGALTGALRALCVLGCLLGHIAAAPSPIIKFPGDVAPKSDKEMAVQYLNTYYG
CPKDKCNLIGLKDALKKMQKFFGLPETGNLDKRTIMTMKKPRCGNPDVANYNFFPRKPKW
EKNEITYRIIGYTPDLDPETVDDAFARAFQVWSNVTPLRFSRIHDGDADIVINFGRWEHG
DGYPFDGKDGLLAHAFAPGPGVGGDSHFDDDELWTLGEGQVVRVKYGTADGEYCKFPFMF
NGKEYNSCTNVGRSDGFLWCSTTYNFDKDNKYGFCPHESLFTLGGNGDGQPCKFPFSFQG
TTYNSCTTEGRSDGYRWCSTTEDYDRDKKYGFCPETAMSTIGGNGNGSPCVFPFTFLGKK
YERCTSDGRSDGKAWCSTTASFDDDRTWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGA
LMAPIYTYTKNFRLSHDDIKGIQELYGPNPDTDTGPGPSPTLGPVTPEICTQDIVFDGIA
QIRGEIFFFKDRFIWRTVTLGEKPTGPLLVATFWPELPDKIDAVYEAPQEEKAVFFAGDE
YWVYSASTLEPGYPKPLTSLGLPPSVKRVDAAFNWSKNKKTYIFAGKKFWRYNEVKKKMD
PDFPKLIEDAWNAIPDDLDAAVDLHAGGYSYFFKSHYYLMLENHSLRNVKLGSIKYDWLG
C
NT seq 1986 nt   +upstreamnt  +downstreamnt
atgatggagacgctcgtggcccggggtgcactcaccggcgcgctgcgggcgctctgcgtc
ctgggctgcctgttgggccacatcgccgctgcgccatcgcccatcatcaagttcccgggt
gatgtcgcccccaaatcggacaaagagatggccgtgcaatacctgaacacctactacggc
tgccccaaggacaagtgcaacctgattgggctgaaggacgcgctgaagaagatgcagaag
ttctttgggctgcctgagacggggaacctcgacaagcgcaccatcatgaccatgaagaag
ccgcgctgcggcaaccccgacgtggccaactacaacttcttcccccgcaagcccaagtgg
gaaaagaacgagatcacgtacaggatcattggctacacacctgaccttgaccccgagacg
gtggatgatgccttcgcccgtgccttccaagtctggagtaacgtgacccccctccggttt
tctcgtatccacgatggagacgccgacatcgtgatcaacttcggccgctgggagcacgga
gatggatacccctttgacggcaaggacgggctcctggctcacgccttcgccccggggcct
ggtgttgggggagactcccactttgacgacgatgagctgtggaccttgggagaagggcaa
gtggtccgagtgaagtacgggaccgccgacggggagtactgtaagttccccttcatgttc
aacggcaaggagtataacagctgcaccaacgtgggccgctcagacggcttcctctggtgt
tccaccacctacaacttcgacaaggacaacaaatacggcttctgcccccatgaatccctg
ttcaccctgggtggcaacggtgacggacagccctgcaagttcccgttcagcttccagggc
accacctacaacagctgcacgaccgagggccgcagcgacggctaccgctggtgcagcacc
acggaggactacgaccgcgacaagaagtacggcttctgcccggagaccgccatgtccacg
atcggcgggaacgggaacggcagcccctgtgtcttccccttcaccttcctgggcaagaag
tacgagcgctgcaccagcgacggccgcagcgacgggaaggcctggtgctccaccaccgcc
agcttcgacgacgaccgcacctggggcttctgccccgaccaagggtacagcctcttcctg
gtggcagctcacgagttcggccacgcgatggggctggagcactcgcaggaccccggagcc
ctgatggcccccatttacacctacaccaagaacttccgcctgtcccatgacgacatcaag
ggcatccaagagctctacgggcccaatcctgacactgacaccggccccggcccttccccc
acgctgggacccgtcactcccgagatctgcacacaagacatcgtctttgacggcatcgct
cagatccgcggggagatcttcttcttcaaggaccggttcatctggcggacagtgacgcta
ggcgagaagcccacggggcccctgctggtggccactttctggcctgagcttccagacaag
atcgatgccgtgtacgaggccccccaggaggagaaggcggtgttctttgcaggggatgag
tactgggtctattcggccagcaccctggagcctgggtaccccaagccgctgaccagcctg
gggctgccccccagtgtgaaacgagtggatgccgcctttaactggagcaagaacaagaag
acatacatctttgctgggaagaagttctggagatacaacgaggtgaagaagaaaatggat
cccgacttccccaagctcatcgaagacgcctggaatgctatccccgatgacctggacgcc
gcggtggacctgcatgctggtggttacagctacttcttcaagagccattattacctgatg
ctggagaatcacagtctgaggaacgtgaagcttggaagcatcaagtatgactggctgggc
tgctga

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