KEGG   Plecotus auritus (brown big-eared bat): 308235451
Entry
308235451         CDS       T11911                                 
Symbol
TGFB1, AC0HY7_002284
Name
(RefSeq) transforming growth factor beta-1 proprotein
  KO
K13375  transforming growth factor beta-1
Organism
pots  Plecotus auritus (brown big-eared bat)
Pathway
pots04010  MAPK signaling pathway
pots04060  Cytokine-cytokine receptor interaction
pots04068  FoxO signaling pathway
pots04110  Cell cycle
pots04148  Efferocytosis
pots04218  Cellular senescence
pots04350  TGF-beta signaling pathway
pots04380  Osteoclast differentiation
pots04390  Hippo signaling pathway
pots04518  Integrin signaling
pots04659  Th17 cell differentiation
pots04672  Intestinal immune network for IgA production
pots04926  Relaxin signaling pathway
pots04932  Non-alcoholic fatty liver disease
pots04933  AGE-RAGE signaling pathway in diabetic complications
pots05140  Leishmaniasis
pots05142  Chagas disease
pots05144  Malaria
pots05145  Toxoplasmosis
pots05146  Amoebiasis
pots05152  Tuberculosis
pots05161  Hepatitis B
pots05166  Human T-cell leukemia virus 1 infection
pots05200  Pathways in cancer
pots05205  Proteoglycans in cancer
pots05210  Colorectal cancer
pots05211  Renal cell carcinoma
pots05212  Pancreatic cancer
pots05220  Chronic myeloid leukemia
pots05225  Hepatocellular carcinoma
pots05226  Gastric cancer
pots05321  Inflammatory bowel disease
pots05323  Rheumatoid arthritis
pots05410  Hypertrophic cardiomyopathy
pots05414  Dilated cardiomyopathy
pots05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pots00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    308235451 (TGFB1)
   04350 TGF-beta signaling pathway
    308235451 (TGFB1)
   04390 Hippo signaling pathway
    308235451 (TGFB1)
   04068 FoxO signaling pathway
    308235451 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    308235451 (TGFB1)
   04518 Integrin signaling
    308235451 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    308235451 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    308235451 (TGFB1)
   04218 Cellular senescence
    308235451 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    308235451 (TGFB1)
   04672 Intestinal immune network for IgA production
    308235451 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    308235451 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    308235451 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    308235451 (TGFB1)
   05205 Proteoglycans in cancer
    308235451 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    308235451 (TGFB1)
   05212 Pancreatic cancer
    308235451 (TGFB1)
   05225 Hepatocellular carcinoma
    308235451 (TGFB1)
   05226 Gastric cancer
    308235451 (TGFB1)
   05220 Chronic myeloid leukemia
    308235451 (TGFB1)
   05211 Renal cell carcinoma
    308235451 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    308235451 (TGFB1)
   05161 Hepatitis B
    308235451 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    308235451 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    308235451 (TGFB1)
   05144 Malaria
    308235451 (TGFB1)
   05145 Toxoplasmosis
    308235451 (TGFB1)
   05140 Leishmaniasis
    308235451 (TGFB1)
   05142 Chagas disease
    308235451 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    308235451 (TGFB1)
   05321 Inflammatory bowel disease
    308235451 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    308235451 (TGFB1)
   05414 Dilated cardiomyopathy
    308235451 (TGFB1)
   05415 Diabetic cardiomyopathy
    308235451 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    308235451 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    308235451 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:pots03110]
    308235451 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pots04052]
    308235451 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:pots00536]
    308235451 (TGFB1)
Chaperones and folding catalysts [BR:pots03110]
 Intramolecular chaperones
  Others
   308235451 (TGFB1)
Cytokines and neuropeptides [BR:pots04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   308235451 (TGFB1)
Glycosaminoglycan binding proteins [BR:pots00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   308235451 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 308235451
NCBI-ProteinID: XP_080500407
LinkDB
Position
10:19870757..19885807
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGDVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLTVDNNHEI
YKAYKHNSHSIYMFFNTSDLREAVPEPELLSRAELRLQRHKLKVEQHVELYQKYGNNTWR
YLSNQLLSPSDTPEWLSFEVTGVVRQWLSHRGEIQGFRLSAHCSCDSKDNTLHVEINGIS
IDRRGDLATIRAINRPFLLLMATPLERAQHLHSPRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcattgaggccatccgcggccagattctgtccaagctgcggctcgcc
agccccccgagccagggggatgtgccgcccggaccgctgccggaggccgtgctggccctt
tacaacagtacccgcgaccgagtggccggggagagcgcggaacccgagcccgagcccgag
gcggactactacgccaaggaggtcacccgcgtgctgaccgtggataacaaccacgaaatc
tataaggcatacaagcacaactcacacagcatatatatgttcttcaacacgtcggatctc
cgggaagcagtgcctgaacccgagttgctctcccgagccgagctgcgcctgcagaggcac
aagttgaaagtggagcaacacgtggagctataccagaaatacggcaacaatacctggcgc
tacctcagcaaccagctgctgtcccccagcgacacgcctgagtggctgtcctttgaggtc
actggagtcgtgcggcagtggctgagccacagaggtgaaatccagggctttcgcctcagt
gcccactgctcctgtgacagcaaagataacacactccatgtggaaatcaacggaatcagt
attgaccgccggggtgacctggccaccattcgtgccataaaccggcccttcctgcttctc
atggctacccctctggagagagcccagcacctgcacagcccccggcaccgccgagccctg
gacaccaactactgcttcagctccacggagaaaaactgctgtgtgcggcagctctacatc
gacttccgcaaggatctgggctggaaatggatccacgagcccaagggctaccatgccaac
ttctgcctggggccctgcccgtacatttggagcctggacacgcagtacagcaaggtcctg
gccctatacaaccagcacaaccccggcgcgtcggcggcgccgtgctgcgtgccgcaggcg
ctggagcccctgcctattgtgtactacgtgggccgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

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